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Structure of Epac2 in complex with a cyclic AMP analogue and RAP1B
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title
Structure of Epac2 in complex with a cyclic AMP analogue and RAP1B
(English)
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main subject
Rap guanine nucleotide exchange factor (GEF) 4
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stated in
GOA release 2020-03-11
author name string
Holger Rehmann
series ordinal
1
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Ernesto Arias-Palomo
series ordinal
2
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Michael A Hadders
series ordinal
3
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Frank Schwede
series ordinal
4
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Oscar Llorca
series ordinal
5
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Johannes L Bos
series ordinal
6
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language of work or name
English
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publication date
4 September 2008
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published in
Nature
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volume
455
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page(s)
124-7
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issue
7209
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cites work
Epac is a Rap1 guanine-nucleotide-exchange factor directly activated by cyclic AMP
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7 January 2021
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A family of cAMP-binding proteins that directly activate Rap1
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7 January 2021
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Linking Rap to cell adhesion
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7 January 2021
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PKA-dependent and PKA-independent pathways for cAMP-regulated exocytosis
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https://api.crossref.org/works/10.1038%2FNATURE07187
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7 January 2021
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Structure of the cyclic-AMP-responsive exchange factor Epac2 in its auto-inhibited state
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7 January 2021
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Ligand-mediated activation of the cAMP-responsive guanine nucleotide exchange factor Epac
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Classification and phylogenetic analysis of the cAMP-dependent protein kinase regulatory subunit family
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Mapping adenosine cyclic 3',5'-phosphate binding sites on type I and type II adenosine cyclic 3',5'-phosphate dependent protein kinases using ribose ring and cyclic phosphate ring analogs of adenosine cyclic 3',5'-phosphate
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Regulatory subunit of protein kinase A: structure of deletion mutant with cAMP binding domains
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Molecular basis for regulatory subunit diversity in cAMP-dependent protein kinase: crystal structure of the type II beta regulatory subunit
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Structural basis of ligand activation in a cyclic nucleotide regulated potassium channel.
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Structural basis for modulation and agonist specificity of HCN pacemaker channels
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Capturing cyclic nucleotides in action: snapshots from crystallographic studies
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Structural evidence for feedback activation by Ras.GTP of the Ras-specific nucleotide exchange factor SOS
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A Ras-induced conformational switch in the Ras activator Son of sevenless
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The structural basis of the activation of Ras by Sos
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Crossref
reference URL
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inferred from DOI database lookup
Characterization of the activation of the Rap-specific exchange factor Epac by cyclic nucleotides.
1 reference
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Crossref
reference URL
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Differential interaction of the ras family GTP-binding proteins H-Ras, Rap1A, and R-Ras with the putative effector molecules Raf kinase and Ral-guanine nucleotide exchange factor
1 reference
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Automatic processing of rotation diffraction data from crystals of initially unknown symmetry and cell constants
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Improved methods for building protein models in electron density maps and the location of errors in these models
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Disentangling conformational states of macromolecules in 3D-EM through likelihood optimization.
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Identifiers
DOI
10.1038/NATURE07187
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
849983
Dimensions Publication ID
1012980434
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OpenCitations bibliographic resource ID
849983
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
849983
PubMed ID
18660803
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
849983
ResearchGate publication ID
51431639
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Springer Nature article ID
10.1038/nature07187
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