(Q24318410)

regulation of mitotic spindle organization

GOA release 2020-03-11

1 reference

TPX2, microtubule-associated

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

Anthony A Hyman

2

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author name string

Alexander W Bird

series ordinal

1

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language of work or name

English

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publication date

28 July 2008

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number of pages

12

1 reference

Spindle pole regulation by a discrete Eg5-interacting domain in TPX2

inferred from page(s)

published in

Journal of Cell Biology

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volume

182

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page(s)

289-300

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issue

2

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cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2483532

HURP controls spindle dynamics to promote proper interkinetochore tension and efficient kinetochore capture.

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2483532

Anaphase-promoting complex/cyclosome controls the stability of TPX2 during mitotic exit

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2483532

Kinetochore-driven formation of kinetochore fibers contributes to spindle assembly during animal mitosis

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2483532

Structural basis of Aurora-A activation by TPX2 at the mitotic spindle

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2483532

Human TPX2 is required for targeting Aurora-A kinase to the spindle

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2483532

Chromatin docking and exchange activity enhancement of RCC1 by histones H2A and H2B

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2483532

Mammalian mad2 and bub1/bubR1 recognize distinct spindle-attachment and kinetochore-tension checkpoints

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2483532

TPX2, A novel xenopus MAP involved in spindle pole organization

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2483532

Identification of a human mitotic checkpoint gene: hsMAD2

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2483532

Catalysis of guanine nucleotide exchange on Ran by the mitotic regulator RCC1

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2483532

Spatial control of mitosis by the GTPase Ran

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2483532

HURP is part of a Ran-dependent complex involved in spindle formation

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2483532

hTPX2 is required for normal spindle morphology and centrosome integrity during vertebrate cell division

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2483532

Centrosome maturation and mitotic spindle assembly in C. elegans require SPD-5, a protein with multiple coiled-coil domains

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2483532

Chromosome-induced microtubule assembly mediated by TPX2 is required for spindle formation in HeLa cells

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2483532

A new logic for DNA engineering using recombination in Escherichia coli

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2483532

Localization of Mad2 to kinetochores depends on microtubule attachment, not tension

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2483532

Self-organization of microtubules into bipolar spindles around artificial chromosomes in Xenopus egg extracts

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2483532

Mitotic spindle organization by a plus-end-directed microtubule motor

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2483532

BAC TransgeneOmics: a high-throughput method for exploration of protein function in mammals

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2483532

Aurora A regulates the activity of HURP by controlling the accessibility of its microtubule-binding domain

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2483532

Aurora-A: the maker and breaker of spindle poles

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2483532

Cooperative mechanisms of mitotic spindle formation

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2483532

Microtubule-organizing centres: a re-evaluation.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2483532

27 September 2017

Flies without centrioles

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2483532

Making microtubules and mitotic spindles in cells without functional centrosomes

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2483532

Molecular requirements for kinetochore-associated microtubule formation in mammalian cells

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2483532

GCP-WD is a gamma-tubulin targeting factor required for centrosomal and chromatin-mediated microtubule nucleation

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2483532

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2483532

The bipolar mitotic kinesin Eg5 moves on both microtubules that it crosslinks

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2483532

RNA interference rescue by bacterial artificial chromosome transgenesis in mammalian tissue culture cells

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2483532

Importin beta is transported to spindle poles during mitosis and regulates Ran-dependent spindle assembly factors in mammalian cells

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2483532

Characterization of the TPX2 domains involved in microtubule nucleation and spindle assembly in Xenopus egg extracts

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2483532

Myosin II-dependent cortical movement is required for centrosome separation and positioning during mitotic spindle assembly

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2483532

Importin alpha-regulated nucleation of microtubules by TPX2.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2483532

Minus-end capture of preformed kinetochore fibers contributes to spindle morphogenesis.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2483532

Recombineering: a powerful new tool for mouse functional genomics

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2483532

Techniques: Recombinogenic engineering--new options for cloning and manipulating DNA.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2483532

Rapid modification of bacterial artificial chromosomes by ET-recombination.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2483532

Sites of microtubule assembly and disassembly in the mitotic spindle

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2483532

The structure of the cold-stable kinetochore fiber in metaphase PtK1 cells

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2483532

A combined approach for the localization and tandem affinity purification of protein complexes from metazoans.

30 May 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200802005

Ran induces spindle assembly by reversing the inhibitory effect of importin alpha on TPX2 activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200802005

Mechanisms of spindle-pole organization are influenced by kinetochore activity in mammalian cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200802005

An essential function of the C. elegans ortholog of TPX2 is to localize activated aurora A kinase to mitotic spindles.

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200802005

Aurora A kinase-coated beads function as microtubule-organizing centers and enhance RanGTP-induced spindle assembly.

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200802005

An improved recombineering approach by adding RecA to lambda Red recombination

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200802005

HURP Is a Ran-Importin β-Regulated Protein that Stabilizes Kinetochore Microtubules in the Vicinity of Chromosomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200802005

The Xenopus laevis aurora-related protein kinase pEg2 associates with and phosphorylates the kinesin-related protein XlEg5

21 January 2018

1 reference

12 December 2020

A Ran signalling pathway mediated by the mitotic kinase Aurora A in spindle assembly

1 reference

12 December 2020

Ran modulates spindle assembly by regulating a subset of TPX2 and Kid activities including Aurora A activation

1 reference

12 December 2020

Regulation ofXenopusAurora A Activation by TPX2

1 reference

12 December 2020

Identifiers

DOI

10.1083/JCB.200802005

1 reference

499232

499232

1 reference

1 reference

1 reference