(Q24319682)

English

Structure determination of tetrahydroquinazoline antifolates in complex with human and Pneumocystis carinii dihydrofolate reductase: correlations between enzyme selectivity and stereochemistry

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title

Structure determination of tetrahydroquinazoline antifolates in complex with human and Pneumocystis carinii dihydrofolate reductase: correlations between enzyme selectivity and stereochemistry (English)

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main subject

dihydrofolate reductase

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stated in

GOA release 2020-03-11

drug binding

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stated in

GOA release 2020-03-11

Pneumocystis carinii

object named as

Pneumocystis carinii

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5

Sherry F Queener

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author name string

Vivian Cody

series ordinal

1

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Joe R Luft

series ordinal

2

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Walt Pangborn

series ordinal

3

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Aleem Gangjee

series ordinal

4

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language of work or name

English

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publication date

April 2004

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published in

Acta Crystallographica Section D: Biological Crystallography

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volume

60

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page(s)

646-55

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issue

Pt 4

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Identifiers

DOI

10.1107/S0907444904002094

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PubMed ID

15039552

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(Q24319682)

Structure determination of tetrahydroquinazoline antifolates in complex with human and Pneumocystis carinii dihydrofolate reductase: correlations between enzyme selectivity and stereochemistry

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