(Q24320018)

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Mutations of mitotic checkpoint genes in human cancers

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Mutations of mitotic checkpoint genes in human cancers (English)

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mitotic cell cycle checkpoint signaling

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GOA release 2020-03-11

Bert Vogelstein

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B Vogelstein

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Kenneth W. Kinzler

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K W Kinzler

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author name string

D P Cahill

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C Lengauer

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J Yu

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G J Riggins

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J K Willson

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S D Markowitz

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publication date

19 March 1998

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392

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6673

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300-3

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Defects in a cell cycle checkpoint may be responsible for the genomic instability of cancer cells

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7 January 2021

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Strand-specific mismatch repair in mammalian cells

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Mismatch repair: mechanisms and relationship to cancer susceptibility

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Lessons from hereditary colorectal cancer

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Genetic instability in colorectal cancers

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Destabilization of tracts of simple repetitive DNA in yeast by mutations affecting DNA mismatch repair

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The genetics of cell cycle checkpoints

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At the heart of the budding yeast cell cycle

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When checkpoints fail

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How cells get the right chromosomes

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Feedback control of mitosis in budding yeast

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The Saccharomyces cerevisiae checkpoint gene BUB1 encodes a novel protein kinase

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https://api.crossref.org/works/10.1038%2F32688

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Activation of the budding yeast spindle assembly checkpoint without mitotic spindle disruption.

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Abnormal kinetochore structure activates the spindle assembly checkpoint in budding yeast

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Kinetochore localization of murine Bub1 is required for normal mitotic timing and checkpoint response to spindle damage

1 reference

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Protein kinase catalytic domain sequence database: identification of conserved features of primary structure and classification of family members

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Identification of a human mitotic checkpoint gene: hsMAD2

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Integrating genetic approaches into the discovery of anticancer drugs

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Uncoupling of S phase and mitosis induced by anticancer agents in cells lacking p21

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Genetic determinants of p53-induced apoptosis and growth arrest

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Mismatch repair gene defects in sporadic colorectal cancers with microsatellite instability

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Large-scale isolation of human 1p36-specific P1 clones and their use for fluorescence in situ hybridization.

1 reference

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Allelic loss of chromosome 18q and prognosis in colorectal cancer

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Mammalian BUB1 protein kinases: map positions and in vivo expression

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based on heuristic

inferred from DOI database lookup

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