(Q24320049)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18313602%20AND%20SRC:MED&resulttype=core&format=json

3 January 2020

title

Gain of function in IKs secondary to a mutation in KCNE5 associated with atrial fibrillation (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18313602%20AND%20SRC:MED&resulttype=core&format=json

Potassium voltage-gated channel subfamily E regulatory subunit 5

3 January 2020

main subject

atrial fibrillation

0 references

1 reference

negative regulation of potassium ion export across plasma membrane

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

author

Charles Antzelevitch

15

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18313602%20AND%20SRC:MED&resulttype=core&format=json

3 January 2020

Yoshiyasu Aizawa

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18313602%20AND%20SRC:MED&resulttype=core&format=json

3 January 2020

Dan Hu

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18313602%20AND%20SRC:MED&resulttype=core&format=json

3 January 2020

Jesper Hastrup Svendsen

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18313602%20AND%20SRC:MED&resulttype=core&format=json

3 January 2020

Charles Antzelevitch

16

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18313602%20AND%20SRC:MED&resulttype=core&format=json

3 January 2020

10

Stig Haunso

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18313602%20AND%20SRC:MED&resulttype=core&format=json

3 January 2020

3

Guido D Pollevick

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18313602%20AND%20SRC:MED&resulttype=core&format=json

3 January 2020

5

Jonathan M Cordeiro

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18313602%20AND%20SRC:MED&resulttype=core&format=json

3 January 2020

9

Elena Burashnikov

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18313602%20AND%20SRC:MED&resulttype=core&format=json

3 January 2020

Alejandra Guerchicoff

11

object named as

Alejandra Guerchicoff

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18313602%20AND%20SRC:MED&resulttype=core&format=json

3 January 2020

author name string

Lasse S Ravn

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18313602%20AND%20SRC:MED&resulttype=core&format=json

3 January 2020

Jacob Hofman-Bang

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18313602%20AND%20SRC:MED&resulttype=core&format=json

3 January 2020

Ulrik Dixen

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18313602%20AND%20SRC:MED&resulttype=core&format=json

3 January 2020

Gorm Jensen

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18313602%20AND%20SRC:MED&resulttype=core&format=json

3 January 2020

Yuesheng Wu

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18313602%20AND%20SRC:MED&resulttype=core&format=json

3 January 2020

Michael Christiansen

14

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18313602%20AND%20SRC:MED&resulttype=core&format=json

3 January 2020

language of work or name

English

0 references

publication date

4 February 2008

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18313602%20AND%20SRC:MED&resulttype=core&format=json

3 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18313602%20AND%20SRC:MED&resulttype=core&format=json

3 January 2020

volume

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18313602%20AND%20SRC:MED&resulttype=core&format=json

3 January 2020

page(s)

427-435

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18313602%20AND%20SRC:MED&resulttype=core&format=json

3 January 2020

issue

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18313602%20AND%20SRC:MED&resulttype=core&format=json

Somatic mutations in the connexin 40 gene (GJA5) in atrial fibrillation

3 January 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2515863

Identification of a KCNE2 gain-of-function mutation in patients with familial atrial fibrillation

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2515863

Ankyrin-B mutation causes type 4 long-QT cardiac arrhythmia and sudden cardiac death

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2515863

KCNQ1 gain-of-function mutation in familial atrial fibrillation

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2515863

KCNE5 induces time- and voltage-dependent modulation of the KCNQ1 current

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2515863

MiRP1 forms IKr potassium channels with HERG and is associated with cardiac arrhythmia

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2515863

Functional modulation of the transient outward current Ito by KCNE beta-subunits and regional distribution in human non-failing and failing hearts

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2515863

Kv1.5 channelopathy due to KCNA5 loss-of-function mutation causes human atrial fibrillation

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2515863

Expression and transcriptional control of human KCNE genes

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2515863

Atrial fibrillation in KCNE1-null mice

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2515863

MinK, MiRP1, and MiRP2 diversify Kv3.1 and Kv3.2 potassium channel gating

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2515863

Lack of association of the potassium channel–associated peptide MiRP2-R83H variant with periodic paralysis

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2515863

A single transmembrane site in the KCNE-encoded proteins controls the specificity of KvLQT1 channel gating

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2515863

MiRP2 forms potassium channels in skeletal muscle with Kv3.4 and is associated with periodic paralysis

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2515863

Structural determinants of KvLQT1 control by the KCNE family of proteins

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2515863

Spectrum of mutations in long-QT syndrome genes. KVLQT1, HERG, SCN5A, KCNE1, and KCNE2

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2515863

KCNE1 mutations cause jervell and Lange-Nielsen syndrome

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2515863

K(V)LQT1 and lsK (minK) proteins associate to form the I(Ks) cardiac potassium current

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2515863

KATP channel mutation confers risk for vein of Marshall adrenergic atrial fibrillation

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2515863

Relation of 97T polymorphism in KCNE5 to risk of atrial fibrillation

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2515863

In vitro molecular interactions and distribution of KCNE family with KCNQ1 in the human heart

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2515863

A Kir2.1 gain-of-function mutation underlies familial atrial fibrillation

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2515863

Is atrial fibrillation a genetic disease?

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2515863

Expression of multiple KCNE genes in human heart may enable variable modulation of I(Ks).

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2515863

Genome-wide linkage scan identifies a novel genetic locus on chromosome 5p13 for neonatal atrial fibrillation associated with sudden death and variable cardiomyopathy

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2515863

Parental atrial fibrillation as a risk factor for atrial fibrillation in offspring

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2515863

Does KCNE5 play a role in long QT syndrome?

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2515863

Potassium channel subunits encoded by the KCNE gene family: physiology and pathophysiology of the MinK-related peptides (MiRPs).

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2515863

Sudden death associated with short-QT syndrome linked to mutations in HERG.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2515863

Familial atrial fibrillation is a genetically heterogeneous disorder.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2515863

Incident stroke after discharge from the hospital with a diagnosis of atrial fibrillation.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2515863

Decrease in mortality in patients with a hospital diagnosis of atrial fibrillation in Denmark during the period 1980-1993.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2515863

KCNE1-like gene is deleted in AMME contiguous gene syndrome: identification and characterization of the human and mouse homologs.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2515863

Identification of a genetic locus for familial atrial fibrillation

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2515863

Familial aggregation of atrial fibrillation in Iceland

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2515863

Left ventricular dysfunction due to atrial fibrillation in patients initially believed to have idiopathic dilated cardiomyopathy

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2515863

De novo KCNQ1 mutation responsible for atrial fibrillation and short QT syndrome in utero.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2515863

Short QT syndrome and atrial fibrillation caused by mutation in KCNH2.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2515863

Prolonged signal-averaged P wave duration after elective cardioversion increases the risk of recurrent atrial fibrillation

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2515863

Mutant MiRP1 subunits modulate HERG K+ channel gating: a mechanism for pro-arrhythmia in long QT syndrome type 6.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2515863

Association of the human minK gene 38G allele with atrial fibrillation: evidence of possible genetic control on the pathogenesis of atrial fibrillation

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2515863

Screening for mutations and polymorphisms in the genes KCNH2 and KCNE2 encoding the cardiac HERG/MiRP1 ion channel: implications for acquired and congenital long Q-T syndrome

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2515863

Locus for atrial fibrillation maps to chromosome 6q14-16

29 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18313602

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

A single strand conformation polymorphism/heteroduplex (SSCP/HD) method for detection of mutations in 15 exons of the KVLQT1 gene, associated with long QT syndrome

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18313602

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Sex-specific increase in the prevalence of atrial fibrillation (The Copenhagen City Heart Study)

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18313602

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.HRTHM.2007.12.019

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18313602%20AND%20SRC:MED&resulttype=core&format=json

3 January 2020

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18313602%20AND%20SRC:MED&resulttype=core&format=json

3 January 2020

2 references