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MNK1 and MNK2 regulation in HER2-overexpressing breast cancer lines
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scholarly article
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title
MNK1 and MNK2 regulation in HER2-overexpressing breast cancer lines
(English)
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main subject
MAPK interacting serine/threonine kinase 1
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stated in
GOA release 2020-03-11
peptidyl-serine phosphorylation
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stated in
GOA release 2020-03-11
overexpression
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based on heuristic
inferred from title
author name string
Carol A Chrestensen
series ordinal
1
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Jacquelyn K Shuman
series ordinal
2
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Andrew Eschenroeder
series ordinal
3
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Mark Worthington
series ordinal
4
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Hermann Gram
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5
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Thomas W Sturgill
series ordinal
6
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language of work or name
English
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publication date
16 February 2007
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published in
Journal of Biological Chemistry
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volume
282
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page(s)
4243-52
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issue
7
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cites work
Translational control of the proteome: relevance to cancer
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stated in
Crossref
reference URL
https://api.crossref.org/works/10.1074%2FJBC.M607368200
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Overexpression of eukaryotic initiation factor 4E (eIF4E) in breast carcinoma
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1074%2FJBC.M607368200
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identification of the human Mnk2 gene (MKNK2) through protein interaction with estrogen receptor beta
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1074%2FJBC.M607368200
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Phosphorylation of eIF-4E on Ser 209 in response to mitogenic and inflammatory stimuli is faithfully detected by specific antibodies
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reference URL
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7 January 2021
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Molecular characterization of the t(3;9) associated with immortalization in the MCF10A cell line
1 reference
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Crossref
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7 January 2021
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Herceptin: mechanisms of action and resistance
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Crossref
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7 January 2021
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A case study in misidentification of cancer cell lines: MCF-7/AdrR cells (re-designated NCI/ADR-RES) are derived from OVCAR-8 human ovarian carcinoma cells
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Crossref
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7 January 2021
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Activation of translation complex eIF4F is essential for the genesis and maintenance of the malignant phenotype in human mammary epithelial cells
1 reference
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Crossref
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7 January 2021
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Drosophila Lk6 kinase controls phosphorylation of eukaryotic translation initiation factor 4E and promotes normal growth and development.
1 reference
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Crossref
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7 January 2021
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Posttranscriptional regulation of TNFalpha expression via eukaryotic initiation factor 4E (eIF4E) phosphorylation in mouse macrophages
1 reference
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reference URL
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The Mnks are novel components in the control of TNF alpha biosynthesis and phosphorylate and regulate hnRNP A1
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stated in
Crossref
reference URL
https://api.crossref.org/works/10.1074%2FJBC.M607368200
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Crystal structures of the Mnk2 kinase domain reveal an inhibitory conformation and a zinc binding site
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Crossref
reference URL
https://api.crossref.org/works/10.1074%2FJBC.M607368200
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7 January 2021
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inferred from DOI database lookup
Identification and molecular characterization of Mnk1b, a splice variant of human MAP kinase-interacting kinase Mnk1
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1074%2FJBC.M607368200
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Phosphorylation of the cap-binding protein eIF4E by the MAPK-activated protein kinase Mnk1.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1074%2FJBC.M607368200
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Role and regulation of 90 kDa ribosomal S6 kinase (RSK) in signal transduction.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1074%2FJBC.M607368200
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7 January 2021
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inferred from DOI database lookup
Phosphorylation of initiation factor 4E is resistant to SB203580 in cells expressing a drug-resistant mutant of stress-activated protein kinase 2a/p38.
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stated in
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reference URL
https://api.crossref.org/works/10.1074%2FJBC.M607368200
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7 January 2021
based on heuristic
inferred from DOI database lookup
Focus on breast cancer
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stated in
Crossref
reference URL
https://api.crossref.org/works/10.1074%2FJBC.M607368200
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
An activity-dependent switch to cap-independent translation triggered by eIF4E dephosphorylation
1 reference
stated in
Crossref
reference URL
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7 January 2021
based on heuristic
inferred from DOI database lookup
PTEN activity could be a predictive marker of trastuzumab efficacy in the treatment of ErbB2-overexpressing breast cancer
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1074%2FJBC.M607368200
retrieved
7 January 2021
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inferred from DOI database lookup
CSF-1 activates MAPK-dependent and p53-independent pathways to induce growth arrest of hormone-dependent human breast cancer cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1074%2FJBC.M607368200
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The serine-threonine kinase MNK1 is post-translationally stabilized by PML-RARalpha and regulates differentiation of hematopoietic cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1074%2FJBC.M607368200
retrieved
7 January 2021
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inferred from DOI database lookup
Regulation of the ABC kinases by phosphorylation: protein kinase C as a paradigm
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1074%2FJBC.M607368200
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7 January 2021
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inferred from DOI database lookup
MSK1 activity is controlled by multiple phosphorylation sites.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1074%2FJBC.M607368200
retrieved
7 January 2021
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inferred from DOI database lookup
The emerging roles of translation factor eIF4E in the nucleus
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1074%2FJBC.M607368200
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7 January 2021
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Constitutive activation of mitogen-activated protein kinase-activated protein kinase 2 by mutation of phosphorylation sites and an A-helix motif
1 reference
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Crossref
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7 January 2021
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Reconstitution of mitogen-activated protein kinase phosphorylation cascades in bacteria. Efficient synthesis of active protein kinases
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1074%2FJBC.M607368200
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7 January 2021
based on heuristic
inferred from DOI database lookup
The phosphorylation of eukaryotic initiation factor eIF4E in response to phorbol esters, cell stresses, and cytokines is mediated by distinct MAP kinase pathways
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1074%2FJBC.M607368200
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7 January 2021
based on heuristic
inferred from DOI database lookup
Identification of regulatory phosphorylation sites in mitogen-activated protein kinase (MAPK)-activated protein kinase-1a/p90rsk that are inducible by MAPK
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1074%2FJBC.M607368200
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7 January 2021
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inferred from DOI database lookup
Intestinal epithelial cell differentiation involves activation of p38 mitogen-activated protein kinase that regulates the homeobox transcription factor CDX2.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1074%2FJBC.M607368200
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7 January 2021
based on heuristic
inferred from DOI database lookup
Characterization of the p90 ribosomal S6 kinase 2 carboxyl-terminal domain as a protein kinase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1074%2FJBC.M607368200
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7 January 2021
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inferred from DOI database lookup
Features in the N and C termini of the MAPK-interacting kinase Mnk1 mediate its nucleocytoplasmic shuttling
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1074%2FJBC.M607368200
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
MAPKAP kinase 2 phosphorylates tristetraprolin on in vivo sites including Ser178, a site required for 14-3-3 binding
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1074%2FJBC.M607368200
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
eIF4E promotes nuclear export of cyclin D1 mRNAs via an element in the 3'UTR
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1074%2FJBC.M607368200
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
FAK signaling is critical for ErbB-2/ErbB-3 receptor cooperation for oncogenic transformation and invasion
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1074%2FJBC.M607368200
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mitogen-activated protein kinases activate the serine/threonine kinases Mnk1 and Mnk2
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1074%2FJBC.M607368200
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
MNK1, a new MAP kinase-activated protein kinase, isolated by a novel expression screening method for identifying protein kinase substrates
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1074%2FJBC.M607368200
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Leptomycin B-sensitive nuclear export of MAPKAP kinase 2 is regulated by phosphorylation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1074%2FJBC.M607368200
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Human eukaryotic translation initiation factor 4G (eIF4G) recruits mnk1 to phosphorylate eIF4E
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1074%2FJBC.M607368200
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Characterization of new estrogen receptor destabilizing compounds: effects on estrogen-sensitive and tamoxifen-resistant breast cancer
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1074%2FJBC.M607368200
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The ELAV RNA-stability factor HuR binds the 5'-untranslated region of the human IGF-IR transcript and differentially represses cap-dependent and IRES-mediated translation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1074%2FJBC.M607368200
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Proteasome inhibitor bortezomib increases PTEN expression and enhances trastuzumab-induced growth inhibition in trastuzumab-resistant cells.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1074%2FJBC.M607368200
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mnk is a negative regulator of cap-dependent translation in Aplysia neurons.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1074%2FJBC.M607368200
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Phosphorylation of the cap-binding protein eukaryotic translation initiation factor 4E by protein kinase Mnk1 in vivo
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1074%2FJBC.M607368200
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Negative regulation of protein translation by mitogen-activated protein kinase-interacting kinases 1 and 2
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1074%2FJBC.M607368200
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The mitogen-activated protein kinase signal-integrating kinase Mnk2 is a eukaryotic initiation factor 4E kinase with high levels of basal activity in mammalian cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1074%2FJBC.M607368200
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The N and C termini of the splice variants of the human mitogen-activated protein kinase-interacting kinase Mnk2 determine activity and localization
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1074%2FJBC.M607368200
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mnk2 and Mnk1 are essential for constitutive and inducible phosphorylation of eukaryotic initiation factor 4E but not for cell growth or development
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1074%2FJBC.M607368200
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Phosphorylation of the eukaryotic translation initiation factor eIF4E contributes to its transformation and mRNA transport activities
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1074%2FJBC.M607368200
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Hyperexpression of mitogen-activated protein kinase in human breast cancer
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1074%2FJBC.M607368200
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Roles of heterogeneous nuclear ribonucleoproteins A and B in cell proliferation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1074%2FJBC.M607368200
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1074/JBC.M607368200
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PubMed ID
17130135
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