(Q24320214)

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Human actin mutations associated with hypertrophic and dilated cardiomyopathies demonstrate distinct thin filament regulatory properties in vitro

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scholarly article

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9 February 2020

Human actin mutations associated with hypertrophic and dilated cardiomyopathies demonstrate distinct thin filament regulatory properties in vitro (English)

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9 February 2020

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based on heuristic

inferred from title

Actin alpha cardiac muscle 1

1 reference

GOA release 2020-03-11

actin-myosin filament sliding

1 reference

GOA release 2020-03-11

Edward P Debold

1

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9 February 2020

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Walid Saber

2

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9 February 2020

Yaser Cheema

3

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9 February 2020

Carol S Bookwalter

4

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9 February 2020

Kathleen M Trybus

5

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9 February 2020

David M Warshaw

6

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9 February 2020

Peter Vanburen

7

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9 February 2020

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publication date

30 September 2009

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9 February 2020

Journal of Molecular and Cellular Cardiology

1 reference

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9 February 2020

48

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9 February 2020

2

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9 February 2020

286-292

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9 February 2020

Functional consequences of a mutation in an expressed human alpha-cardiac actin at a site implicated in familial hypertrophic cardiomyopathy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2813351

19 March 2017

The myosin power stroke

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2813351

19 March 2017

The genetic basis for cardiomyopathy: from mutation identification to mechanistic paradigms

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2813351

19 March 2017

Inherited and de novo mutations in the cardiac actin gene cause hypertrophic cardiomyopathy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2813351

19 March 2017

Regulation of the interaction between actin and myosin subfragment 1: evidence for three states of the thin filament

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2813351

19 March 2017

Regulation of force and unloaded sliding speed in single thin filaments: effects of regulatory proteins and calcium

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2813351

19 March 2017

Regulation of cardiac hypertrophy by intracellular signalling pathways

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2813351

7 April 2017

Structural basis for the regulation of muscle contraction by troponin and tropomyosin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2813351

27 September 2017

Differential interactions of thin filament proteins in two cardiac troponin T mouse models of hypertrophic and dilated cardiomyopathies.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2813351

27 September 2017

Hypertrophic and dilated cardiomyopathy mutations differentially affect the molecular force generation of mouse alpha-cardiac myosin in the laser trap assay

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2813351

27 September 2017

Structure of the mid-region of tropomyosin: bending and binding sites for actin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2813351

27 September 2017

Single-myosin crossbridge interactions with actin filaments regulated by troponin-tropomyosin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2813351

27 September 2017

Activation of the Calcium-Regulated Thin Filament by Myosin Strong Binding

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2813351

27 September 2017

A mutant heterodimeric myosin with one inactive head generates maximal displacement

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2813351

27 September 2017

The Genetic Basis for Cardiomyopathy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2813351

27 September 2017

Kinetic differences at the single molecule level account for the functional diversity of rabbit cardiac myosin isoforms

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2813351

27 September 2017

Alpha-cardiac actin is a novel disease gene in familial hypertrophic cardiomyopathy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2813351

27 September 2017

Smooth muscle and skeletal muscle myosins produce similar unitary forces and displacements in the laser trap

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2813351

27 September 2017

Calcium regulation of thin filament movement in an in vitro motility assay

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2813351

27 September 2017

Measuring kinetics of complex single ion channel data using mean-variance histograms

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2813351

27 September 2017

ADP dissociation from actomyosin subfragment 1 is sufficiently slow to limit the unloaded shortening velocity in vertebrate muscle

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2813351

27 September 2017

Sliding filaments and molecular motile systems.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2813351

27 September 2017

The energetics of allosteric regulation of ADP release from myosin heads

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2813351

30 May 2018

Role of residues 311/312 in actin-tropomyosin interaction. In vitro motility study using yeast actin mutant e311a/r312a

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2813351

30 May 2018

Dynamics of the muscle thin filament regulatory switch: the size of the cooperative unit.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2813351

30 May 2018

MCP-1 induces cardioprotection against ischaemia/reperfusion injury: role of reactive oxygen species

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2813351

29 November 2018

E93K charge reversal on actin perturbs steric regulation of thin filaments

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2813351

29 November 2018

Clinical and genetic characteristics of alpha cardiac actin gene mutations in hypertrophic cardiomyopathy.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2813351

29 November 2018

Prevalence and spectrum of thin filament mutations in an outpatient referral population with hypertrophic cardiomyopathy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2813351

29 November 2018

Cardiac troponin T isoforms demonstrate similar effects on mechanical performance in a regulated contractile system

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2813351

29 November 2018

Troponin organization on relaxed and activated thin filaments revealed by electron microscopy and three-dimensional reconstruction11Edited by W. Baumeister

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2813351

29 November 2018

Steric-model for activation of muscle thin filaments 1 1 Edited by P.E. Wright

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2813351

29 November 2018

An atomic model of the unregulated thin filament obtained by X-ray fiber diffraction on oriented actin-tropomyosin gels.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2813351

29 November 2018

Preparation of troponin and its subunits.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2813351

29 November 2018

Hypertrophic cardiomyopathy: a common cause of sudden death in the young competitive athlete

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2009.09.014

7 January 2021

Assessment of Diastolic Function With Doppler Tissue Imaging to Predict Genotype in Preclinical Hypertrophic Cardiomyopathy

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2009.09.014

7 January 2021

7 Preparation of myosin and its subfragments from rabbit skeletal muscle

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2009.09.014

7 January 2021

Cardiac myosin isoforms from different species have unique enzymatic and mechanical properties

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2009.09.014

7 January 2021

Separation and characterization of the two functional regions of troponin involved in muscle thin filament regulation

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2009.09.014

7 January 2021

Comparison of the myosin and actomyosin ATPase mechanisms of the four types of vertebrate muscles

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2009.09.014

7 January 2021

Cooperation within actin filament in vertebrate skeletal muscle

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2009.09.014

7 January 2021

Cross-bridge interaction kinetics in rat myocardium are accelerated by strong binding of myosin to the thin filament

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2009.09.014

7 January 2021

Identifiers

10.1016/J.YJMCC.2009.09.014

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19799913%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

1 reference

Europe PubMed Central

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9 February 2020

1 reference

Europe PubMed Central

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9 February 2020

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