(Q30494542)

13 August 2017

A mutant heterodimeric myosin with one inactive head generates maximal displacement (English)

1 reference

13 August 2017

Neil M Kad

1

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author name string

Arthur S Rovner

2

1 reference

13 August 2017

Patricia M Fagnant

3

1 reference

13 August 2017

Peteranne B Joel

4

1 reference

13 August 2017

Guy G Kennedy

5

1 reference

13 August 2017

Joseph B Patlak

6

1 reference

13 August 2017

David M Warshaw

7

1 reference

13 August 2017

Kathleen M Trybus

8

1 reference

13 August 2017

language of work or name

English

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publication date

1 August 2003

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13 August 2017

Journal of Cell Biology

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13 August 2017

162

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13 August 2017

3

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13 August 2017

481-488

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Two functional heads are required for full activation of smooth muscle myosin

13 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2172693

Coordination of kinesin's two heads studied with mutant heterodimers

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2172693

Coordination of the two heads of myosin during muscle contraction

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2172693

Class VI myosin moves processively along actin filaments backward with large steps

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2172693

Three-dimensional image reconstruction of dephosphorylated smooth muscle heavy meromyosin reveals asymmetry in the interaction between myosin heads and placement of subfragment 2

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2172693

Coiled-coil unwinding at the smooth muscle myosin head-rod junction is required for optimal mechanical performance

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2172693

Single-molecule tracking of myosins with genetically engineered amplifier domains.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2172693

Biochemical studies of myosin

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2172693

Two conserved lysines at the 50/20-kDa junction of myosin are necessary for triggering actin activation

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2172693

Three conformational states of scallop myosin S1

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2172693

Characterization of single actomyosin rigor bonds: load dependence of lifetime and mechanical properties

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2172693

Single-molecule mechanics of R403Q cardiac myosin isolated from the mouse model of familial hypertrophic cardiomyopathy

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2172693

Dynamic measurement of myosin light-chain-domain tilt and twist in muscle contraction.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2172693

Two heads of myosin are better than one for generating force and motion.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2172693

Cooperativity between two heads of dictyostelium myosin II in in vitro motility and ATP hydrolysis

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2172693

Smooth muscle myosin. Amino acid residues responsible for the hydrolysis of ATP.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2172693

Crystal structure of a vertebrate smooth muscle myosin motor domain and its complex with the essential light chain: visualization of the pre-power stroke state

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2172693

The stiffness of rabbit skeletal actomyosin cross-bridges determined with an optical tweezers transducer.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2172693

Cooperativity between the two heads of rabbit skeletal muscle heavy meromyosin in binding to actin.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2172693

Functional transitions in myosin: formation of a critical salt-bridge and transmission of effect to the sensitive tryptophan.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2172693

Quick-freeze deep-etch electron microscopy of the actin-heavy meromyosin complex during the in vitro motility assay.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2172693

A large and distinct rotation of the myosin light chain domain occurs upon muscle contraction

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2172693

Unconventional myosins in cell movement, membrane traffic, and signal transduction

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2172693

Actin filament mechanics in the laser trap

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2172693

An insert in the motor domain determines the functional properties of expressed smooth muscle myosin isoforms

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2172693

Smooth muscle and skeletal muscle myosins produce similar unitary forces and displacements in the laser trap

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2172693

Myosin motors with artificial lever arms

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2172693

Xenopus nonmuscle myosin heavy chain isoforms have different subcellular localizations and enzymatic activities

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2172693

The neck region of the myosin motor domain acts as a lever arm to generate movement

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2172693

Chimeric substitutions of the actin-binding loop activate dephosphorylated but not phosphorylated smooth muscle heavy meromyosin

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2172693

Movement of actin away from the center of reconstituted rabbit myosin filament is slower than in the opposite direction

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2172693

Three-dimensional structure of myosin subfragment-1: a molecular motor

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2172693

Single myosin molecule mechanics: piconewton forces and nanometre steps

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2172693

The role of three-state docking of myosin S1 with actin in force generation.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2172693

Measuring kinetics of complex single ion channel data using mean-variance histograms

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2172693

Movement and force produced by a single myosin head.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2172693

An electrophoretic study of the low-molecular-weight components of myosin

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2172693

The use of actin labelled with N-(1-pyrenyl)iodoacetamide to study the interaction of actin with myosin subfragments and troponin/tropomyosin

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2172693

Crossbridge behaviour during muscle contraction

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2172693

Complete primary structure of vertebrate smooth muscle myosin heavy chain deduced from its complementary DNA sequence. Implications on topography and function of myosin.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2172693

Bidirectional movement of actin filaments along tracks of myosin heads

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2172693

Evidence for the association between two myosin heads in rigor acto-smooth muscle heavy meromyosin

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2172693

Monoclonal antibodies detect and stabilize conformational states of smooth muscle myosin

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2172693

Smooth muscle myosin cross-bridge interactions modulate actin filament sliding velocity in vitro

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2172693

Mutations in cardiac myosin heavy chain genes cause familial hypertrophic cardiomyopathy

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2172693

Neonatal and adult myosin heavy chains form homodimers during avian skeletal muscle development

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2172693

Analysis of the chicken fast myosin heavy chain family. Localization of isoform-specific antibody epitopes and regions of divergence

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2172693

Interaction of myosin subfragments with F-actin

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2172693

Generation of force by single-headed myosin

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2172693

A 7-amino-acid insert in the heavy chain nucleotide binding loop alters the kinetics of smooth muscle myosin in the laser trap

28 July 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200304023

Role of the lever arm in the processive stepping of myosin V.

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200304023

Myosin VI is a processive motor with a large step size

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200304023

The Two Heads of Smooth Muscle Myosin Are Enzymatically Independent but Mechanically Interactive

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200304023

Mutational analysis of the switch II loop of Dictyostelium myosin II.

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200304023

The myosin relay helix to converter interface remains intact throughout the actomyosin ATPase cycle

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200304023

Swing of the lever arm of a myosin motor at the isomerization and phosphate-release steps.

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200304023

Orientation dependence of displacements by a single one-headed myosin relative to the actin filament

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200304023

The gated gait of the processive molecular motor, myosin V.

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200304023

Visualization of head-head interactions in the inhibited state of smooth muscle myosin

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200304023

Modification of the bi-directional sliding movement of actin filaments along native thick filaments isolated from a clam.

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200304023

Sliding movement of single actin filaments on one-headed myosin filaments

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200304023

Myosin subfragment-1 is sufficient to move actin filaments in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200304023

Substructure of the myosin molecule. IV. Interactions of myosin and its subfragments with adenosine triphosphate and F-actin

21 January 2018

1 reference

12 December 2020

SH1 (cysteine 717) of smooth muscle myosin: its role in motor function

1 reference

12 December 2020

Comparison of the myosin and actomyosin ATPase mechanisms of the four types of vertebrate muscles

1 reference

12 December 2020

Polarity and velocity of sliding filaments: control of direction by actin and of speed by myosin

1 reference

12 December 2020

Smooth, cardiac and skeletal muscle myosin force and motion generation assessed by cross-bridge mechanical interactions in vitro

1 reference

12 December 2020

Two heads are required for phosphorylation-dependent regulation of smooth muscle myosin

1 reference

12 December 2020

Identifiers

DOI

10.1083/JCB.200304023

1 reference

13 August 2017

1 reference

13 August 2017

PubMed publication ID

12900396

1 reference