(Q24320239)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19935646%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

title

Cancer-associated IDH1 mutations produce 2-hydroxyglutarate (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19935646%20AND%20SRC:MED&resulttype=core&format=json

Isocitrate dehydrogenase (NADP(+)) 1

12 February 2020

main subject

1 reference

protein homodimerization activity

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

author

Robert M. Prins

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19935646%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

Patrick S. Ward

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19935646%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

Linda Liau

15

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19935646%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

Lewis C. Cantley

17

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19935646%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

18

Craig B Thompson

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19935646%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

author name string

Lenny Dang

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19935646%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

David W White

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19935646%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

Stefan Gross

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19935646%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

Bryson D Bennett

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19935646%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

Mark A Bittinger

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19935646%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

Edward M Driggers

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19935646%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

Valeria R Fantin

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19935646%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

Hyun Gyung Jang

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19935646%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

Shengfang Jin

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19935646%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

Marie C Keenan

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19935646%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

Kevin M Marks

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19935646%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

Katharine E Yen

14

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19935646%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

Joshua D Rabinowitz

16

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19935646%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

Matthew G Vander Heiden

19

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19935646%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

Shinsan M Su

20

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19935646%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

language of work or name

English

0 references

publication date

1 December 2009

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19935646%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19935646%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

volume

462

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19935646%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

page(s)

739-744

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19935646%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

issue

7274

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19935646%20AND%20SRC:MED&resulttype=core&format=json

Recurring mutations found by sequencing an acute myeloid leukemia genome

12 February 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2818760

IDH1 mutations are early events in the development of astrocytomas and oligodendrogliomas

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2818760

IDH1 and IDH2 mutations in gliomas

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2818760

An integrated genomic analysis of human glioblastoma multiforme

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2818760

Mutations in the D-2-hydroxyglutarate dehydrogenase gene cause D-2-hydroxyglutaric aciduria

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2818760

Coot: model-building tools for molecular graphics

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2818760

The CCP4 suite: programs for protein crystallography

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2818760

Structures of human cytosolic NADP-dependent isocitrate dehydrogenase reveal a novel self-regulatory mechanism of activity

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2818760

Glioma-derived mutations in IDH1 dominantly inhibit IDH1 catalytic activity and induce HIF-1alpha

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2818760

IDH1 mutations at residue p.R132 (IDH1(R132)) occur frequently in high-grade gliomas but not in other solid tumors

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2818760

Analysis of the IDH1 codon 132 mutation in brain tumors

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2818760

Hydroxyglutaric aciduria and malignant brain tumor: a case report and literature review

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2818760

Systems-level metabolic flux profiling identifies fatty acid synthesis as a target for antiviral therapy

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2818760

The role of oxidative damage in the neuropathology of organic acidurias: insights from animal studies.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2818760

White matter disease in cerebral organic acid disorders: clinical implications and suggested pathomechanisms

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2818760

Metabolic signaling between neurons and glial cells: a short review

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2818760

Type and frequency of IDH1 and IDH2 mutations are related to astrocytic and oligodendroglial differentiation and age: a study of 1,010 diffuse gliomas.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2818760

A lysine-tyrosine pair carries out acid-base chemistry in the metal ion-dependent pyridine dinucleotide-linked beta-hydroxyacid oxidative decarboxylases

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2818760

Simultaneous determination of multiple intracellular metabolites in glycolysis, pentose phosphate pathway and tricarboxylic acid cycle by liquid chromatography-mass spectrometry.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2818760

A high-performance liquid chromatography-tandem mass spectrometry method for quantitation of nitrogen-containing intracellular metabolites

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2818760

Measurement of urinary D- and L-2-hydroxyglutarate enantiomers by stable-isotope-dilution liquid chromatography-tandem mass spectrometry after derivatization with diacetyl-L-tartaric anhydride

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2818760

D-2-hydroxyglutaric acid induces oxidative stress in cerebral cortex of young rats

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2818760

NMDA receptor activation and respiratory chain complex V inhibition contribute to neurodegeneration in d-2-hydroxyglutaric aciduria

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2818760

Processing of X-ray diffraction data collected in oscillation mode

29 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19935646

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Phasercrystallographic software

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNATURE08617

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/NATURE08617

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19935646%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

12 February 2020

1016136939

0 references

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19935646%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

2 references