(Q24321619)

English

Gain-of-function mutation of Nav1.5 in atrial fibrillation enhances cellular excitability and lowers the threshold for action potential firing

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19167345%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

Gain-of-function mutation of Nav1.5 in atrial fibrillation enhances cellular excitability and lowers the threshold for action potential firing (English)

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19167345%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

atrial fibrillation

0 references

Sodium voltage-gated channel alpha subunit 5

1 reference

GOA release 2020-03-11

regulation of atrial cardiac muscle cell membrane repolarization

1 reference

GOA release 2020-03-11

Michael H. Gollob

10

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19167345%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

author name string

Qiuju Li

1

1 reference

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19167345%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

Hai Huang

2

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19167345%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

Gele Liu

3

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19167345%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

Khanh Lam

4

1 reference

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19167345%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

Julie Rutberg

5

1 reference

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19167345%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

Martin S Green

6

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19167345%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

David H Birnie

7

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19167345%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

Robert Lemery

8

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19167345%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

Mohamed Chahine

9

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20 January 2020

language of work or name

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publication date

22 January 2009

1 reference

Europe PubMed Central

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20 January 2020

Biochemical and Biophysical Research Communications

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19167345%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

380

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Europe PubMed Central

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20 January 2020

1

1 reference

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20 January 2020

132-137

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19167345%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

A novel muscle sodium channel mutation causes painful congenital myotonia

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBRC.2009.01.052

7 January 2021

based on heuristic

inferred from DOI database lookup

SCN5A mutations associated with an inherited cardiac arrhythmia, long QT syndrome

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBRC.2009.01.052

7 January 2021

based on heuristic

inferred from DOI database lookup

A Kir2.1 gain-of-function mutation underlies familial atrial fibrillation

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBRC.2009.01.052

7 January 2021

based on heuristic

inferred from DOI database lookup

Functional expression of "cardiac-type" Nav1.5 sodium channel in canine intracardiac ganglia.

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBRC.2009.01.052

7 January 2021

based on heuristic

inferred from DOI database lookup

Cardiac sodium channel mutation in atrial fibrillation

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBRC.2009.01.052

7 January 2021

based on heuristic

inferred from DOI database lookup

A novel SCN5A gain-of-function mutation M1875T associated with familial atrial fibrillation

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBRC.2009.01.052

7 January 2021

based on heuristic

inferred from DOI database lookup

Contributions of charged residues in a cytoplasmic linking region to Na channel gating

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBRC.2009.01.052

7 January 2021

based on heuristic

inferred from DOI database lookup

Human SCN5A gene mutations alter cardiac sodium channel kinetics and are associated with the Brugada syndrome.

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBRC.2009.01.052

7 January 2021

based on heuristic

inferred from DOI database lookup

A gain-of-function mutation in the sodium channel gene Scn2a results in seizures and behavioral abnormalities.

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBRC.2009.01.052

7 January 2021

based on heuristic

inferred from DOI database lookup

Sodium currents in isolated rat CA1 pyramidal and dentate granule neurones in the post-status epilepticus model of epilepsy

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBRC.2009.01.052

7 January 2021

based on heuristic

inferred from DOI database lookup

Molecular and functional changes in voltage-dependent Na(+) channels following pilocarpine-induced status epilepticus in rat dentate granule cells

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBRC.2009.01.052

7 January 2021

based on heuristic

inferred from DOI database lookup

Sodium currents in isolated rat CA1 neurons after kindling epileptogenesis

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBRC.2009.01.052

7 January 2021

based on heuristic

inferred from DOI database lookup

Cardiac conduction defects associate with mutations in SCN5A

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBRC.2009.01.052

7 January 2021

based on heuristic

inferred from DOI database lookup

Genetic basis and molecular mechanism for idiopathic ventricular fibrillation

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBRC.2009.01.052

7 January 2021

based on heuristic

inferred from DOI database lookup

Molecular mechanism for an inherited cardiac arrhythmia

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBRC.2009.01.052

7 January 2021

based on heuristic

inferred from DOI database lookup

Voltage-gated sodium channels in epilepsy.

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBRC.2009.01.052

7 January 2021

based on heuristic

inferred from DOI database lookup

Spontaneous initiation of atrial fibrillation by ectopic beats originating in the pulmonary veins

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBRC.2009.01.052

7 January 2021

based on heuristic

inferred from DOI database lookup

Somatic mutations in the connexin 40 gene (GJA5) in atrial fibrillation

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBRC.2009.01.052

7 January 2021

based on heuristic

inferred from DOI database lookup

Amino acid residues required for fast Na(+)-channel inactivation: charge neutralizations and deletions in the III-IV linker

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBRC.2009.01.052

7 January 2021

based on heuristic

inferred from DOI database lookup

A cluster of hydrophobic amino acid residues required for fast Na(+)-channel inactivation

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBRC.2009.01.052

7 January 2021

based on heuristic

inferred from DOI database lookup

Identification of a KCNE2 gain-of-function mutation in patients with familial atrial fibrillation

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBRC.2009.01.052

7 January 2021

based on heuristic

inferred from DOI database lookup

Kv1.5 channelopathy due to KCNA5 loss-of-function mutation causes human atrial fibrillation

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBRC.2009.01.052

7 January 2021

based on heuristic

inferred from DOI database lookup

Carbamazepine effects on Na+ currents in human dentate granule cells from epileptogenic tissue

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBRC.2009.01.052

7 January 2021

based on heuristic

inferred from DOI database lookup

Modulation of sodium currents in rat CA1 neurons by carbamazepine and valproate after kindling epileptogenesis

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBRC.2009.01.052

7 January 2021

based on heuristic

inferred from DOI database lookup

Different flecainide sensitivity of hNav1.4 channels and myotonic mutants explained by state-dependent block

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBRC.2009.01.052

7 January 2021

based on heuristic

inferred from DOI database lookup

Carbamazepine inhibition of neuronal Na+ currents: quantitative distinction from phenytoin and possible therapeutic implications

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBRC.2009.01.052

7 January 2021

based on heuristic

inferred from DOI database lookup

KCNQ1 gain-of-function mutation in familial atrial fibrillation

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBRC.2009.01.052

7 January 2021

based on heuristic

inferred from DOI database lookup

Increased neuronal excitability and seizures in the Na(+)/H(+) exchanger null mutant mouse

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBRC.2009.01.052

7 January 2021

based on heuristic

inferred from DOI database lookup

Pulmonary vein denervation enhances long-term benefit after circumferential ablation for paroxysmal atrial fibrillation

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBRC.2009.01.052

7 January 2021

based on heuristic

inferred from DOI database lookup

Cardiac sodium channel (SCN5A) variants associated with atrial fibrillation

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBRC.2009.01.052

7 January 2021

based on heuristic

inferred from DOI database lookup

Novel mechanism for Brugada syndrome: defective surface localization of an SCN5A mutant (R1432G).

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBRC.2009.01.052

7 January 2021

based on heuristic

inferred from DOI database lookup

Inherited disorders of voltage-gated sodium channels

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBRC.2009.01.052

7 January 2021

based on heuristic

inferred from DOI database lookup

Atrial-selective sodium channel block as a strategy for suppression of atrial fibrillation

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBRC.2009.01.052

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1016/J.BBRC.2009.01.052

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19167345%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19167345%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

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