(Q44649200)

5 December 2017

Different flecainide sensitivity of hNav1.4 channels and myotonic mutants explained by state-dependent block (English)

1 reference

5 December 2017

2

1 reference

5 December 2017

Diana Camerino Conte

5

0 references

Jean-François Desaphy

series ordinal

1

object named as

Jean-François Desaphy

1 reference

5 December 2017

3

Maria Paola Didonna

1 reference

5 December 2017

Alfred L George

4

1 reference

PubMed ID

14608015

5 December 2017

language of work or name

English

0 references

publication date

7 November 2003

1 reference

5 December 2017

Journal of Physiology

1 reference

5 December 2017

554

1 reference

5 December 2017

Pt 2

1 reference

5 December 2017

321-334

1 reference

Molecular pharmacology of the sodium channel mutation D1790G linked to the long-QT syndrome

5 December 2017

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2003.046995

Lidocaine block of cardiac sodium channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2003.046995

Characterization of a new sodium channel mutation at arginine 1448 associated with moderate Paramyotonia congenita in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2003.046995

Effects of flecainide in patients with new SCN5A mutation: mutation-specific therapy for long-QT syndrome?

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2003.046995

Voltage sensors in domains III and IV, but not I and II, are immobilized by Na+ channel fast inactivation

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2003.046995

Gating of myotonic Na channel mutants defines the response to mexiletine and a potent derivative

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2003.046995

Different ability of clenbuterol and salbutamol to block sodium channels predicts their therapeutic use in muscle excitability disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2003.046995

Two human paramyotonia congenita mutations have opposite effects on lidocaine block of Na+ channels expressed in a mammalian cell line

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2003.046995

Effects of temperature and mexiletine on the F1473S Na+ channel mutation causing paramyotonia congenita

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2003.046995

Block of wild-type and inactivation-deficient cardiac sodium channels IFM/QQQ stably expressed in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2003.046995

Differential effects of homologous S4 mutations in human skeletal muscle sodium channels on deactivation gating from open and inactivated states.

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2003.046995

Interaction between fast and ultra-slow inactivation in the voltage-gated sodium channel. Does the inactivation gate stabilize the channel structure?

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2003.046995

Local anesthetics: hydrophilic and hydrophobic pathways for the drug-receptor reaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2003.046995

Paramyotonia congenita mutations reveal different roles for segments S3 and S4 of domain D4 in hSkM1 sodium channel gating

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2003.046995

Skeletal muscle channelopathies

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2003.046995

Na+ channels must deactivate to recover from inactivation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2003.046995

Common molecular determinants of flecainide and lidocaine block of heart Na+ channels: evidence from experiments with neutral and quaternary flecainide analogues

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2003.046995

Channel openings are necessary but not sufficient for use-dependent block of cardiac Na(+) channels by flecainide: evidence from the analysis of disease-linked mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2003.046995

Myopathic mutations affect differently the inactivation of the two gating modes of sodium channels.

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2003.046995

States and sites of actions of flecainide on guinea-pig cardiac sodium channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2003.046995

Isoform-specific lidocaine block of sodium channels explained by differences in gating

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2003.046995

Cardiac sodium channels (hH1) are intrinsically more sensitive to block by lidocaine than are skeletal muscle (mu 1) channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2003.046995

Molecular determinants of drug access to the receptor site for antiarrhythmic drugs in the cardiac Na+ channel

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2003.046995

Common molecular determinants of local anesthetic, antiarrhythmic, and anticonvulsant block of voltage-gated Na+ channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2003.046995

Gating of skeletal and cardiac muscle sodium channels in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2003.046995

Molecular action of lidocaine on the voltage sensors of sodium channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2003.046995

Mexiletine block of disease-associated mutations in S6 segments of the human skeletal muscle Na(+) channel

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2003.046995

Slow inactivation in voltage-gated sodium channels: molecular substrates and contributions to channelopathies

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2003.046995

Gating-dependent mechanisms for flecainide action in SCN5A-linked arrhythmia syndromes

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2003.046995

Distinct local anesthetic affinities in Na+ channel subtypes

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2003.046995

Functional consequences of a domain 1/S6 segment sodium channel mutation associated with painful congenital myotonia

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2003.046995

Different effects of mexiletine on two mutant sodium channels causing paramyotonia congenita and hyperkalemic periodic paralysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2003.046995

Differences in steady-state inactivation between Na channel isoforms affect local anesthetic binding affinity

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2003.046995

Sodium channel mutations in paramyotonia congenita exhibit similar biophysical phenotypes in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2003.046995

Multiple gating modes and the effect of modulating factors on the μI sodium channel

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2003.046995

Preferential block of late sodium current in the LQT3 DeltaKPQ mutant by the class I(C) antiarrhythmic flecainide.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1664778

Differential interaction of R-mexiletine with the local anesthetic receptor site on brain and heart sodium channel alpha-subunits.

3 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1664778

Subgroups of class 1 antiarrhythmic drugs

3 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1664778

The site of action and active form of local anesthetics. II. Experiments with quaternary compounds

3 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1664778

Interactions of flecainide with guinea pig cardiac sodium channels. Importance of activation unblocking to the voltage dependence of recovery

3 November 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2003.046995

Mutations of sodium channels in periodic paralysis: can they explain the disease and predict treatment?

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2003.046995

Defective slow inactivation of sodium channels contributes to familial periodic paralysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2003.046995

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2003.046995

A novel muscle sodium channel mutation causes painful congenital myotonia

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2003.046995

Guidelines 2000 for Cardiopulmonary Resuscitation and Emergency Cardiovascular Care. Part 6: advanced cardiovascular life support: section 5: pharmacology I: agents for arrhythmias. The American Heart Association in collaboration with the Internatio

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/14608015

inferred from PubMed ID database lookup

12 December 2020

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Identifiers

DOI

10.1113/JPHYSIOL.2003.046995

1 reference

release_tpm5dguzrrholf2ul54xx7aqei

5 December 2017

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/tpm5dguzrrholf2ul54xx7aqei

mapped directly with Wikidata item

24 November 2022

based on heuristic

0 references

1 reference

PubMed ID

14608015