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Minor spliceosome components are predominantly localized in the nucleus
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scholarly article
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title
Minor spliceosome components are predominantly localized in the nucleus
(English)
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main subject
spliceosome
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Small nuclear ribonucleoprotein U1 subunit 70
1 reference
stated in
GOA release 2020-03-11
Splicing factor 3b subunit 1
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stated in
GOA release 2020-03-11
Small nuclear ribonucleoprotein U11/U12 subunit 35
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stated in
GOA release 2020-03-11
Small nuclear ribonucleoprotein U11/U12 subunit 25
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stated in
GOA release 2020-03-11
RNA binding region (RNP1, RRM) containing 3
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stated in
GOA release 2020-03-11
LSM1 homolog, mRNA degradation associated
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stated in
GOA release 2020-03-11
RNA-binding region (RNP1, RRM) containing 3
1 reference
stated in
GOA release 2020-03-11
Small nuclear ribonucleoprotein 70 (U1)
1 reference
stated in
GOA release 2020-03-11
Small nuclear ribonucleoprotein 25 (U11/U12)
1 reference
stated in
GOA release 2020-03-11
LSM1 homolog, mRNA degradation associated
1 reference
stated in
GOA release 2020-03-11
Small nuclear ribonucleoprotein 35 (U11/U12)
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stated in
GOA release 2020-03-11
Splicing factor 3B subunit 1
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stated in
GOA release 2020-03-11
Splicing factor 1
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stated in
GOA release 2020-03-11
Thioredoxin-like 4A
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stated in
GOA release 2020-03-11
Splicing factor 3A subunit 2
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stated in
GOA release 2020-03-11
author
Reinhard Georg Lührmann
series ordinal
9
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Janne J Turunen
object named as
Janne J Turunen
series ordinal
8
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Nina Perälä
object named as
Nina Perälä
series ordinal
6
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Claudia Schneider
object named as
Claudia Schneider
series ordinal
4
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Nicholas J Watkins
object named as
Nicholas J Watkins
series ordinal
5
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Mikko J Frilander
object named as
Mikko J Frilander
series ordinal
10
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Cindy L Will
series ordinal
2
object named as
Cindy L Will
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author name string
Heli K J Pessa
series ordinal
1
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Xiaojuan Meng
series ordinal
3
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Mariann Nymark
series ordinal
7
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language of work or name
English
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publication date
24 June 2008
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published in
Proceedings of the National Academy of Sciences of the United States of America
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volume
105
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page(s)
8655-60
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issue
25
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on focus list of Wikimedia project
ScienceSource
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cites work
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The human 18S U11/U12 snRNP contains a set of novel proteins not found in the U2-dependent spliceosome
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Protein 61K, encoded by a gene (PRPF31) linked to autosomal dominant retinitis pigmentosa, is required for U4/U6*U5 tri-snRNP formation and pre-mRNA splicing
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A Sm-like protein complex that participates in mRNA degradation
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PubMed Central
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19 March 2017
Identification, characterization and crystal structure analysis of the human spliceosomal U5 snRNP-specific 15 kD protein
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19 March 2017
A doughnut-shaped heteromer of human Sm-like proteins binds to the 3'-end of U6 snRNA, thereby facilitating U4/U6 duplex formation in vitro
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Additional low-abundance human small nuclear ribonucleoproteins: U11, U12, etc
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U5 small nuclear ribonucleoprotein: RNA structure analysis and ATP-dependent interaction with U4/U6
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Splicing segregation: the minor spliceosome acts outside the nucleus and controls cell proliferation
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PubMed Central
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19 March 2017
Splicing of a rare class of introns by the U12-dependent spliceosome
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PubMed Central
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Biogenesis of small nuclear RNPs
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Identification of an evolutionarily divergent U11 small nuclear ribonucleoprotein particle in Drosophila
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Spliceosomal UsnRNP biogenesis, structure and function
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19 March 2017
Highly diverged U4 and U6 small nuclear RNAs required for splicing rare AT-AC introns
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PubMed Central
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19 March 2017
A novel spliceosome containing U11, U12, and U5 snRNPs excises a minor class (AT-AC) intron in vitro
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PubMed Central
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19 March 2017
Cap trimethylation of U snRNA is cytoplasmic and dependent on U snRNP protein binding
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19 March 2017
Pre-mRNA splicing: awash in a sea of proteins
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The abundance of the spliceosomal snRNPs is not limiting the splicing of U12-type introns
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27 September 2017
The Cajal body: a meeting place for spliceosomal snRNPs in the nuclear maze
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27 September 2017
Escaping the nuclear confines: signal-dependent pre-mRNA splicing in anucleate platelets
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PubMed Central
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27 September 2017
snRNAs contain specific SMN-binding domains that are essential for snRNP assembly
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PubMed Central
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27 September 2017
Splicing double: insights from the second spliceosome
1 reference
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PubMed Central
reference URL
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27 September 2017
Protein composition of human prespliceosomes isolated by a tobramycin affinity-selection method
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2438382
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27 September 2017
The splicing of U12-type introns can be a rate-limiting step in gene expression
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2438382
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27 September 2017
Human U4/U6.U5 and U4atac/U6atac.U5 tri-snRNPs exhibit similar protein compositions
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2438382
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27 September 2017
A computational scan for U12-dependent introns in the human genome sequence
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2438382
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27 September 2017
Functions of SR proteins in the U12-dependent AT-AC pre-mRNA splicing pathway.
1 reference
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PubMed Central
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27 September 2017
A limited number of pseudouridine residues in the human atac spliceosomal UsnRNAs as compared to human major spliceosomal UsnRNAs
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2438382
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27 September 2017
Nucleoplasmic organization of small nuclear ribonucleoproteins in cultured human cells.
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2438382
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27 September 2017
Nucleo-cytoplasmic transport of U snRNPs: definition of a nuclear location signal in the Sm core domain that binds a transport receptor independently of the m3G cap.
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2438382
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27 September 2017
An abundant U6 snRNP found in germ cells and embryos of Xenopus laevis
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2438382
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27 September 2017
Domains of U4 and U6 snRNAs required for snRNP assembly and splicing complementation in Xenopus oocytes
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PubMed Central
reference URL
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27 September 2017
Poly(A) RNA codistribution with microfilaments: evaluation by in situ hybridization and quantitative digital imaging microscopy
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PubMed Central
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27 September 2017
U6 snRNA maturation and stability
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2438382
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27 September 2017
Cloning and identification of a novel human RNPC3 gene that encodes a protein with two RRM domains and is expressed in the cell nucleus
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2438382
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30 May 2018
Identification of both shared and distinct proteins in the major and minor spliceosomes
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2438382
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30 May 2018
Structure of the small nuclear RNP particle U1: identification of the two structural protuberances with RNP-antigens A and 70K
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2438382
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30 May 2018
The Lsm2-8 complex determines nuclear localization of the spliceosomal U6 snRNA.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1073%2FPNAS.0803646105
retrieved
21 January 2018
Identifiers
DOI
10.1073/PNAS.0803646105
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ADS bibcode
2008PNAS..105.8655P
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PMCID
2438382
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PubMed ID
18559850
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ResearchGate publication ID
5296570
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