(Q24329165)

English

Tumor suppressor FLCN inhibits tumorigenesis of a FLCN-null renal cancer cell line and regulates expression of key molecules in TGF-beta signaling

scientific article

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scholarly article

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20573232%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

Tumor suppressor FLCN inhibits tumorigenesis of a FLCN-null renal cancer cell line and regulates expression of key molecules in TGF-beta signaling (English)

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20573232%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

1 reference

GOA release 2020-03-11

Transforming growth factor beta 2

1 reference

GOA release 2020-03-11

Inhibin subunit beta A

1 reference

GOA release 2020-03-11

transforming growth factor beta 1

1 reference

GOA release 2020-03-11

bone morphogenetic protein 4

1 reference

GOA release 2020-03-11

positive regulation of transcription by RNA polymerase II

1 reference

GOA release 2020-03-11

cancer cell line

1 reference

based on heuristic

inferred from title

6

1 reference

Europe PubMed Central

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6 February 2020

author name string

Seung-Beom Hong

1

1 reference

Europe PubMed Central

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6 February 2020

HyoungBin Oh

2

1 reference

Europe PubMed Central

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6 February 2020

Vladimir A Valera

3

1 reference

Europe PubMed Central

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6 February 2020

Jaime Stull

4

1 reference

Europe PubMed Central

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6 February 2020

Duy-Tan Ngo

5

1 reference

Europe PubMed Central

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6 February 2020

Maria J Merino

7

1 reference

Europe PubMed Central

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6 February 2020

W Marston Linehan

8

1 reference

Europe PubMed Central

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6 February 2020

Laura S Schmidt

9

1 reference

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6 February 2020

language of work or name

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publication date

23 June 2010

1 reference

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6 February 2020

Molecular Cancer

1 reference

Europe PubMed Central

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6 February 2020

9

1 reference

Europe PubMed Central

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6 February 2020

160

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6 February 2020

1

0 references

https://scigraph.springernature.com/pub.10.1186/1476-4598-9-160

1 reference

9 September 2019

https://scigraph.springernature.com/pub.10.1186/1476-4598-9-160

Identification and characterization of a novel folliculin-interacting protein FNIP2

1 reference

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19 March 2017

BHD mutations, clinical and molecular genetic investigations of Birt-Hogg-Dubé syndrome: a new series of 50 families and a review of published reports

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2907329

19 March 2017

Folliculin encoded by the BHD gene interacts with a binding protein, FNIP1, and AMPK, and is involved in AMPK and mTOR signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2907329

19 March 2017

Inactivation of the type II TGF-beta receptor in colon cancer cells with microsatellite instability

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2907329

19 March 2017

Mechanisms of TGF-beta signaling from cell membrane to the nucleus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2907329

19 March 2017

Primer3 on the WWW for general users and for biologist programmers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2907329

19 March 2017

Homozygous loss of BHD causes early embryonic lethality and kidney tumor development with activation of mTORC1 and mTORC2

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2907329

19 March 2017

Kidney-targeted Birt-Hogg-Dube gene inactivation in a mouse model: Erk1/2 and Akt-mTOR activation, cell hyperproliferation, and polycystic kidneys

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2907329

19 March 2017

Mutations in a novel gene lead to kidney tumors, lung wall defects, and benign tumors of the hair follicle in patients with the Birt-Hogg-Dubé syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2907329

19 March 2017

Role of transforming growth factor-beta signaling in cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2907329

19 March 2017

Renal tumour suppressor function of the Birt-Hogg-Dubé syndrome gene product folliculin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2907329

19 March 2017

The role of the Birt-Hogg-Dubé protein in mTOR activation and renal tumorigenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2907329

19 March 2017

Deficiency of FLCN in mouse kidney led to development of polycystic kidneys and renal neoplasia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2907329

19 March 2017

Activin signaling and its role in regulation of cell proliferation, apoptosis, and carcinogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2907329

19 March 2017

DPC4, a candidate tumor suppressor gene at human chromosome 18q21.1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2907329

7 April 2017

The UOK 257 cell line: a novel model for studies of the human Birt-Hogg-Dubé gene pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2907329

27 September 2017

Activin A: autocrine regulator of kidney development and repair

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2907329

27 September 2017

Thrombospondin-1 expression in urothelial carcinoma: prognostic significance and association with p53 alterations, tumour angiogenesis and extracellular matrix components

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2907329

27 September 2017

Germline BHD-mutation spectrum and phenotype analysis of a large cohort of families with Birt-Hogg-Dubé syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2907329

27 September 2017

A germ-line insertion in the Birt-Hogg-Dubé (BHD) gene gives rise to the Nihon rat model of inherited renal cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2907329

27 September 2017

Clinical and genetic studies of Birt-Hogg-Dubé syndrome.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2907329

27 September 2017

Thrombospondin 1 protein expression relates to good prognostic indices in ductal carcinoma in situ of the breast

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2907329

27 September 2017

Birt-Hogg-Dubé syndrome, a genodermatosis associated with spontaneous pneumothorax and kidney neoplasia, maps to chromosome 17p11.2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2907329

27 September 2017

Hereditary Multiple Fibrofolliculomas With Trichodiscomas and Acrochordons

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2907329

27 September 2017

TGF-beta receptor signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2907329

30 May 2018

Hypermethylation of the thrombospondin-1 gene is associated with poor prognosis in penile squamous cell carcinoma.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2907329

29 November 2018

The Birt-Hogg-Dube and tuberous sclerosis complex homologs have opposing roles in amino acid homeostasis in Schizosaccharomyces pombe.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2907329

29 November 2018

The Drosophila homolog of the human tumor suppressor gene BHD interacts with the JAK-STAT and Dpp signaling pathways in regulating male germline stem cell maintenance.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2907329

29 November 2018

High frequency of somatic frameshift BHD gene mutations in Birt-Hogg-Dubé-associated renal tumors.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2907329

29 November 2018

Loss of the Smad3 expression increases susceptibility to tumorigenicity in human gastric cancer.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2907329

29 November 2018

A mutation in the canine BHD gene is associated with hereditary multifocal renal cystadenocarcinoma and nodular dermatofibrosis in the German Shepherd dog.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2907329

29 November 2018

Risk of renal and colonic neoplasms and spontaneous pneumothorax in the Birt-Hogg-Dubé syndrome.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2907329

29 November 2018

Birt-Hogg-Dubé syndrome: mapping of a novel hereditary neoplasia gene to chromosome 17p12-q11.2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2907329

29 November 2018

Birt-Hogg-Dubé syndrome: a novel marker of kidney neoplasia.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2907329

29 November 2018

Comparative mutational analysis of DPC4 (Smad4) in prostatic and colorectal carcinomas

1 reference

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29 November 2018

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29 November 2018

Mutations of the transforming growth factor-beta type II receptor gene and genomic instability in hereditary nonpolyposis colorectal cancer.

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29 November 2018

Birt-Hogg-Dubé syndrome: clinical and genetic studies of 20 families

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Renal Tumors in the Birt-Hogg-Dubé Syndrome

1 reference

https://pubmed.ncbi.nlm.nih.gov/20573232

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Somatic alterations of the DPC4 gene in human colorectal cancers in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/20573232

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of Thrombospondin-1 in Resected Colorectal Liver Metastases Predicts Poor Prognosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/20573232

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1186/1476-4598-9-160

2 references

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20573232%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

Dimensions Publication ID

1 reference

9 September 2019

https://scigraph.springernature.com/pub.10.1186/1476-4598-9-160

OpenCitations bibliographic resource ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

2 references

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20573232%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

2 references

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20573232%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

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