(Q55044062)

16 June 2018

title

The Birt-Hogg-Dube and tuberous sclerosis complex homologs have opposing roles in amino acid homeostasis in Schizosaccharomyces pombe. (English)

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16 June 2018

negative regulation of L-methionine import across plasma membrane

main subject

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L-methionine import across plasma membrane

GO:1905625

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methionine import across plasma membrane

GO:1905544

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positive regulation of L-methionine import across plasma membrane

GO:1903692

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regulation of L-methionine import across plasma membrane

GO:1905626

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Schizosaccharomyces pombe

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object named as

Schizosaccharomyces pombe

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based on heuristic

inferred from title

author name string

Marjon van Slegtenhorst

1

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16 June 2018

Damir Khabibullin

2

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16 June 2018

Tiffiney R Hartman

3

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16 June 2018

Emmanuelle Nicolas

4

1 reference

16 June 2018

Warren D Kruger

5

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16 June 2018

Elizabeth Petri Henske

6

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16 June 2018

language of work or name

English

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publication date

7 June 2007

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16 June 2018

Journal of Biological Chemistry

published in

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16 June 2018

volume

282

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16 June 2018

issue

34

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16 June 2018

page(s)

24583-24590

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16 June 2018

Birt-Hogg-Dubé syndrome: a novel marker of kidney neoplasia.

cites work

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M700857200

Mutations in a novel gene lead to kidney tumors, lung wall defects, and benign tumors of the hair follicle in patients with the Birt-Hogg-Dubé syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M700857200

Clinical and genetic studies of Birt-Hogg-Dubé syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M700857200

A 4-bp deletion in the Birt-Hogg-Dubé gene (FLCN) causes dominantly inherited spontaneous pneumothorax

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M700857200

Germline BHD-mutation spectrum and phenotype analysis of a large cohort of families with Birt-Hogg-Dubé syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M700857200

High frequency of somatic frameshift BHD gene mutations in Birt-Hogg-Dubé-associated renal tumors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M700857200

A germ-line insertion in the Birt-Hogg-Dubé (BHD) gene gives rise to the Nihon rat model of inherited renal cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M700857200

A mutation in the canine BHD gene is associated with hereditary multifocal renal cystadenocarcinoma and nodular dermatofibrosis in the German Shepherd dog.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M700857200

Rheb GTPase is a direct target of TSC2 GAP activity and regulates mTOR signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M700857200

Rheb binds tuberous sclerosis complex 2 (TSC2) and promotes S6 kinase activation in a rapamycin- and farnesylation-dependent manner

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M700857200

Insulin activation of Rheb, a mediator of mTOR/S6K/4E-BP signaling, is inhibited by TSC1 and 2

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M700857200

Tuberous sclerosis complex gene products, Tuberin and Hamartin, control mTOR signaling by acting as a GTPase-activating protein complex toward Rheb

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M700857200

Rheb is a direct target of the tuberous sclerosis tumour suppressor proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M700857200

Rheb promotes cell growth as a component of the insulin/TOR signalling network

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M700857200

Rheb is an essential regulator of S6K in controlling cell growth in Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M700857200

Protein farnesylation is critical for maintaining normal cell morphology and canavanine resistance in Schizosaccharomyces pombe

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M700857200

Pas1, a G1 cyclin, regulates amino acid uptake and rescues a delay in G1 arrest in Tsc1 and Tsc2 mutants in Schizosaccharomyces pombe

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M700857200

Fission yeast Tor2 links nitrogen signals to cell proliferation and acts downstream of the Rheb GTPase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M700857200

Point mutations in TOR confer Rheb-independent growth in fission yeast and nutrient-independent mammalian TOR signaling in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M700857200

Opposite effects of tor1 and tor2 on nitrogen starvation responses in fission yeast

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M700857200

Loss of the TOR kinase Tor2 mimics nitrogen starvation and activates the sexual development pathway in fission yeast.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M700857200

Regulation of leucine uptake by tor1+ in Schizosaccharomyces pombe is sensitive to rapamycin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M700857200

Tsc1+ and tsc2+ regulate arginine uptake and metabolism in Schizosaccharomyces pombe

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M700857200

Folliculin encoded by the BHD gene interacts with a binding protein, FNIP1, and AMPK, and is involved in AMPK and mTOR signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M700857200

mTOR and cancer: insights into a complex relationship

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M700857200

Growing roles for the mTOR pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M700857200

21 January 2018

Identifiers

DOI

10.1074/JBC.M700857200

1 reference

16 June 2018

1 reference

16 June 2018