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The structure of human 5-lipoxygenase
scientific article
The Structure of Human 5-Lipoxygenase
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instance of
scholarly article
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title
The structure of human 5-lipoxygenase
(English)
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main subject
Arachidonate 5-lipoxygenase
1 reference
stated in
GOA release 2020-03-11
leukotriene biosynthetic process
1 reference
stated in
GOA release 2020-03-11
author
Alan R. Brash
series ordinal
6
object named as
A R Brash
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author name string
Nathaniel C Gilbert
series ordinal
1
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Sue G Bartlett
series ordinal
2
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Maria T Waight
series ordinal
3
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David B Neau
series ordinal
4
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William E Boeglin
series ordinal
5
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Marcia E Newcomer
series ordinal
7
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language of work or name
English
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publication date
14 January 2011
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published in
Science
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volume
331
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page(s)
217-9
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issue
6014
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cites work
Crystal structure of inhibitor-bound human 5-lipoxygenase-activating protein
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3245680
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19 March 2017
Requirement of a 5-lipoxygenase-activating protein for leukotriene synthesis
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PubMed Central
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19 March 2017
The 1.85 Å Structure of an 8 R -Lipoxygenase Suggests a General Model for Lipoxygenase Product Specificity
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PubMed Central
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19 March 2017
Conformational flexibility in mammalian 15S-lipoxygenase: Reinterpretation of the crystallographic data
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PubMed Central
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19 March 2017
Crystal structure of a human membrane protein involved in cysteinyl leukotriene biosynthesis
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PubMed Central
reference URL
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19 March 2017
Structural basis for synthesis of inflammatory mediators by human leukotriene C4 synthase
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PubMed Central
reference URL
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19 March 2017
The structure of mammalian 15-lipoxygenase reveals similarity to the lipases and the determinants of substrate specificity
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PubMed Central
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19 March 2017
Crystal structure of soybean lipoxygenase L-1 at 1.4 A resolution
1 reference
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PubMed Central
reference URL
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19 March 2017
CASTp: computed atlas of surface topography of proteins with structural and topographical mapping of functionally annotated residues
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PubMed Central
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19 March 2017
Calcium binding to 5-lipoxygenase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3245680
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19 March 2017
5-Lipoxygenase: mechanisms of regulation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3245680
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27 September 2017
What's all the FLAP about?: 5-lipoxygenase-activating protein inhibitors for inflammatory diseases
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PubMed Central
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27 September 2017
Improving protein crystal quality by selective removal of a Ca(2+)-dependent membrane-insertion loop
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PubMed Central
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27 September 2017
Biosynthesis and metabolism of leukotrienes
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stated in
PubMed Central
reference URL
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27 September 2017
Control of oxygenation in lipoxygenase and cyclooxygenase catalysis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3245680
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27 September 2017
Solution structure of p53 core domain: structural basis for its instability
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stated in
PubMed Central
reference URL
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27 September 2017
Molecular basis of the specific subcellular localization of the C2-like domain of 5-lipoxygenase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3245680
retrieved
27 September 2017
The N-terminal "beta-barrel" domain of 5-lipoxygenase is essential for nuclear membrane translocation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3245680
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27 September 2017
Determinants of 5-lipoxygenase nuclear localization using green fluorescent protein/5-lipoxygenase fusion proteins
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stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3245680
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27 September 2017
Enzyme with dual lipoxygenase activities catalyzes leukotriene A4 synthesis from arachidonic acid
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3245680
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27 September 2017
Kinetic mechanism of guinea pig neutrophil 5-lipoxygenase.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3245680
retrieved
30 May 2018
Investigation of the mechanism of non-turnover-dependent inactivation of purified human 5-lipoxygenase. Inactivation by H2O2 and inhibition by metal ions
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3245680
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30 May 2018
Insights from the X-ray crystal structure of coral 8R-lipoxygenase: calcium activation via a C2-like domain and a structural basis of product chirality
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stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3245680
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29 November 2018
Kinetic Studies of Oxygen Reactivity in Soybean Lipoxygenase-1
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3245680
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29 November 2018
Amino acid differences in the deduced 5-lipoxygenase sequence of CAST atherosclerosis-resistance mice confer impaired activity when introduced into the human ortholog.
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stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3245680
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29 November 2018
Alterations of lipoxygenase specificity by targeted substrate modification and site-directed mutagenesis
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stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3245680
retrieved
29 November 2018
Steric control of oxygenation regiochemistry in soybean lipoxygenase-1.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3245680
retrieved
29 November 2018
Stabilization of purified human 5-lipoxygenase with glutathione peroxidase and superoxide dismutase
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/21233389
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
A single active site residue directs oxygenation stereospecificity in lipoxygenases: stereocontrol is linked to the position of oxygenation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1126%2FSCIENCE.1197203
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1126/SCIENCE.1197203
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
5070632
ADS bibcode
2011Sci...331..217G
0 references
OpenCitations bibliographic resource ID
5070632
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
5070632
PMCID
3245680
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
5070632
PubMed ID
21233389
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
5070632
ResearchGate publication ID
49753911
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