(Q24337045)

English

Posttranslationally processed structure of the human platelet protein smg p21B: evidence for geranylgeranylation and carboxyl methylation of the C-terminal cysteine

scientific article

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scholarly article

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Posttranslationally processed structure of the human platelet protein smg p21B: evidence for geranylgeranylation and carboxyl methylation of the C-terminal cysteine (English)

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protein structure

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RAP1B, member of RAS oncogene family

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GOA release 2020-03-11

author name string

M Kawata

1

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C C Farnsworth

2

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Y Yoshida

3

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M H Gelb

4

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J A Glomset

5

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Y Takai

6

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language of work or name

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publication date

November 1990

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Proceedings of the National Academy of Sciences of the United States of America

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87

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22

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8960-4

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Posttranslational modification of the Ha-ras oncogene protein: evidence for a third class of protein carboxyl methyltransferases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=55080

19 March 2017

Nucleotide sequence of a human cDNA encoding a ras-related protein (rap1B)

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=55080

19 March 2017

A ras-related gene with transformation suppressor activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=55080

19 March 2017

In vitro posttranslational modification of lamin B cloned from a human T-cell line

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=55080

19 March 2017

Molecular cloning of smg p21B and identification of smg p21 purified from bovine brain and human platelets as smg p21B

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=55080

19 March 2017

A novel small molecular weight GTP-binding protein with the same putative effector domain as the ras proteins in bovine brain membranes. Purification, determination of primary structure, and characterization

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=55080

19 March 2017

Human cDNAs rap1 and rap2 homologous to the Drosophila gene Dras3 encode proteins closely related to ras in the 'effector' region

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=55080

19 March 2017

All ras proteins are polyisoprenylated but only some are palmitoylated

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=55080

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=55080

7 April 2017

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=55080

7 April 2017

Isolation and characterization of a cDNA clone for the gamma subunit of bovine retinal transducin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=55080

27 September 2017

p21ras is modified by a farnesyl isoprenoid

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=55080

27 September 2017

Post-translational processing of p21ras is two-step and involves carboxyl-methylation and carboxy-terminal proteolysis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=55080

27 September 2017

ras GTPase activating protein: signal transmitter and signal terminator

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=55080

27 September 2017

Inhibition of purified p21ras farnesyl:protein transferase by Cys-AAX tetrapeptides

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=55080

27 September 2017

Prenyl proteins in eukaryotic cells: a new type of membrane anchor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=55080

27 September 2017

Farnesol modification of Kirsten-ras exon 4B protein is essential for transformation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=55080

27 September 2017

Inhibition of the ras p21 GTPase-activating protein-stimulated GTPase activity of c-Ha-ras p21 by smg p21 having the same putative effector domain as ras p21s

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=55080

27 September 2017

G protein gamma subunits contain a 20-carbon isoprenoid

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=55080

27 September 2017

Brain G protein gamma subunits contain an all-trans-geranylgeranylcysteine methyl ester at their carboxyl termini

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=55080

27 September 2017

Tissue and subcellular distributions of the smg-21/rap1/Krev-1 proteins which are partly distinct from those of c-ras p21s

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=55080

27 September 2017

Human lamin B contains a farnesylated cysteine residue

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=55080

30 May 2018

The membrane-binding domain of a 23-kDa G-protein is carboxyl methylated

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=55080

30 May 2018

A G protein gamma subunit shares homology with ras proteins.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=55080

30 May 2018

Small molecular weight GTP-binding proteins in human platelet membranes. Purification and characterization of a novel GTP-binding protein with a molecular weight of 22,000.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=55080

30 May 2018

Inhibition of GTPase activating protein stimulation of Ras-p21 GTPase by the Krev-1 gene product

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=55080

30 May 2018

RAS2 protein of Saccharomyces cerevisiae undergoes removal of methionine at N terminus and removal of three amino acids at C terminus.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=55080

29 November 2018

Purification and characterization from bovine brain cytosol of two GTPase-activating proteins specific for smg p21, a GTP-binding protein having the same effector domain as c-ras p21s

1 reference

https://pubmed.ncbi.nlm.nih.gov/2123345

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of a major GTP-binding protein in bovine aortic smooth muscle membranes as smg p21, a GTP-binding protein having the same effector domain as ras p21s

1 reference

https://pubmed.ncbi.nlm.nih.gov/2123345

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Peptidal Sex Hormones Inducing Conjugation Tube Formation in Compatible Mating-Type Cells of Tremella mesenterica

1 reference

https://pubmed.ncbi.nlm.nih.gov/2123345

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Farnesylated γ-subunit of photoreceptor G protein indispensable for GTP-binding

1 reference

https://pubmed.ncbi.nlm.nih.gov/2123345

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phosphorylation by cyclic AMP-dependent protein kinase of a human platelet Mr 22,000 GTP-binding protein (smg p21) having the same putative effector domain as the ras gene products

1 reference

https://pubmed.ncbi.nlm.nih.gov/2123345

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phosphorylation of smg p21, a ras p21-like GTP-binding protein, by cyclic AMP-dependent protein kinase in a cell-free system and in response to prostaglandin E1 in intact human platelets

1 reference

https://pubmed.ncbi.nlm.nih.gov/2123345

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structure of Saccharomyces cerevisiae mating hormone a-factor. Identification of S-farnesyl cysteine as a structural component

1 reference

https://pubmed.ncbi.nlm.nih.gov/2123345

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

GTPase activating proteins for the smg-21 GTP-binding protein having the same effector domain as the ras proteins in human platelets

1 reference

https://pubmed.ncbi.nlm.nih.gov/2123345

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Isolation of human platelets and platelet surface membranes

1 reference

https://pubmed.ncbi.nlm.nih.gov/2123345

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of a platelet Mr 22,000 GTP-binding protein as the novel smg-21 gene product having the same putative effector domain as the ras gene products

1 reference

https://pubmed.ncbi.nlm.nih.gov/2123345

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1073/PNAS.87.22.8960

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1990PNAS...87.8960K

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PMC publication ID

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PubMed publication ID

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ResearchGate publication ID

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