(Q21103244)

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P61224

Ras-related protein Rap1

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P61224

Small GTP-binding protein domain family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

1 reference

13 November 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61224

1 reference

9 May 2019

GDP binding

1 reference

8 April 2019

The Rap-RapGAP complex: GTP hydrolysis without catalytic glutamine and arginine residues

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61224

GTP binding

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61224

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61224

8 April 2019

8 April 2019

The Rap-RapGAP complex: GTP hydrolysis without catalytic glutamine and arginine residues

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61224

protein binding

9 references

9 May 2019

Structure of Epac2 in complex with a cyclic AMP analogue and RAP1B

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61224

9 May 2019

The Rap-RapGAP complex: GTP hydrolysis without catalytic glutamine and arginine residues

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61224

9 May 2019

Heart of glass anchors Rasip1 at endothelial cell-cell junctions to support vascular integrity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61224

9 May 2019

WNT-3a modulates platelet function by regulating small GTPase activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61224

9 May 2019

Toward an understanding of the protein interaction network of the human liver

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61224

9 May 2019

A proteome-scale map of the human interactome network

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61224

9 May 2019

The Rap-RapGAP complex: GTP hydrolysis without catalytic glutamine and arginine residues

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61224

9 May 2019

Structure of the cyclic-AMP-responsive exchange factor Epac2 in its auto-inhibited state

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61224

9 May 2019

Structure of Epac2 in complex with a cyclic AMP analogue and RAP1B

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61224

GTPase activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61224

3 references

9 May 2019

9 May 2019

The Rap-RapGAP complex: GTP hydrolysis without catalytic glutamine and arginine residues

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61224

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61224

GTP binding

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61224

4 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61224

9 May 2019

9 May 2019

The Rap-RapGAP complex: GTP hydrolysis without catalytic glutamine and arginine residues

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61224

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61224

cell component

cytoplasm

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61224

1 reference

9 May 2019

membrane

Posttranslationally processed structure of the human platelet protein smg p21B: evidence for geranylgeranylation and carboxyl methylation of the C-terminal cysteine

4 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61224

9 May 2019

Molecular cloning of smg p21B and identification of smg p21 purified from bovine brain and human platelets as smg p21B

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61224

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61224

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61224

9 May 2019

cell-cell junction

1 reference

9 May 2019

CCM1 regulates vascular-lumen organization by inducing endothelial polarity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61224

lipid droplet

1 reference

9 May 2019

Identification of major proteins in the lipid droplet-enriched fraction isolated from the human hepatocyte cell line HuH7

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61224

intracellular anatomical structure

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61224

1 reference

9 May 2019

cell junction

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61224

1 reference

9 May 2019

membrane raft

1 reference

9 May 2019

Targeting of the small GTPase Rap2b, but not Rap1b, to lipid rafts is promoted by palmitoylation at Cys176 and Cys177 and is required for efficient protein activation in human platelets

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61224

extracellular exosome

3 references

17 October 2017

Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT)

http://www.ebi.ac.uk/QuickGO/annotations?protein=P61224&geneProductId=UniProtKB:P61224

17 October 2017

MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis

http://www.ebi.ac.uk/QuickGO/annotations?protein=P61224&geneProductId=UniProtKB:P61224

17 October 2017

Proteomic analysis of podocyte exosome-enriched fraction from normal human urine

http://www.ebi.ac.uk/QuickGO/annotations?protein=P61224&geneProductId=UniProtKB:P61224

azurophil granule membrane

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61224

1 reference

9 May 2019

extracellular exosome

HDA

plasma membrane

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61224

3 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61224

9 May 2019

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61224

establishment of endothelial barrier

biological process

1 reference

9 May 2019

Epac1 and PDZ-GEF cooperate in Rap1 mediated endothelial junction control

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61224

microvillus assembly

1 reference

9 May 2019

Rap2A links intestinal cell polarity to brush border formation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61224

regulation of cell junction assembly

1 reference

9 May 2019

Epac1 and PDZ-GEF cooperate in Rap1 mediated endothelial junction control

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61224

Rap protein signal transduction

1 reference

17 October 2017

Epac1 and PDZ-GEF cooperate in Rap1 mediated endothelial junction control

http://www.ebi.ac.uk/QuickGO/annotations?protein=P61224&geneProductId=UniProtKB:P61224

regulation of establishment of cell polarity

1 reference

9 May 2019

CCM1 regulates vascular-lumen organization by inducing endothelial polarity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61224

cellular response to cAMP

1 reference

8 April 2019

Epac1 and PDZ-GEF cooperate in Rap1 mediated endothelial junction control

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61224

signal transduction

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61224

1 reference

9 May 2019

neutrophil degranulation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61224

1 reference

9 May 2019

interleukin-12-mediated signaling pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61224

1 reference

9 May 2019

small GTPase mediated signal transduction

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61224

cell population proliferation

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61224

response to carbohydrate

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61224

negative regulation of calcium ion-dependent exocytosis

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61224

positive regulation of ERK1 and ERK2 cascade

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61224

cellular response to organic cyclic compound

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61224

cellular response to gonadotropin-releasing hormone

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61224

negative regulation of synaptic vesicle exocytosis

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61224

Rap protein signal transduction

Epac1 and PDZ-GEF cooperate in Rap1 mediated endothelial junction control

3 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61224

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61224

9 May 2019

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61224

small GTP-binding protein domain

has part(s)

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P61224

Identifiers

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

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30 May 2020

1 reference

30 May 2020

1 reference

13 November 2019

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9 August 2016

1 reference

9 August 2016

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9 August 2016

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9 August 2016

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9 August 2016

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9 August 2016

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9 August 2016

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9 August 2016

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9 August 2016

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9 August 2016

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9 August 2016