(Q24337412)

English

Interaction of the p85 subunit of PI 3-kinase and its N-terminal SH2 domain with a PDGF receptor phosphorylation site: structural features and analysis of conformational changes

scientific article published on December 1, 1992

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scholarly article

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Interaction of the p85 subunit of PI 3-kinase and its N-terminal SH2 domain with a PDGF receptor phosphorylation site: structural features and analysis of conformational changes (English)

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phosphorylation

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based on heuristic

inferred from title

protein secondary structure

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1330535

14 September 2022

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T L Blundell

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G. Panayotou

1

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1330535

14 September 2022

B. Bax

2

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14 September 2022

I. Gout

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14 September 2022

M. Federwisch

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14 September 2022

B. Wroblowski

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14 September 2022

R. Dhand

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14 September 2022

M. J. Fry

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0000-0001-8518-1370

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14 September 2022

T. L. Blundell

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14 September 2022

A. Wollmer

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14 September 2022

M. D. Waterfield

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14 September 2022

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December 1992

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https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/1330535/?tool=EBI

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14 September 2022

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/1330535/pdf/?tool=EBI

Portable Document Format

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14 September 2022

https://europepmc.org/articles/PMC556998

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Europe PubMed Central

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1330535

14 September 2022

https://europepmc.org/articles/PMC556998?pdf=render

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Europe PubMed Central

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1330535

14 September 2022

The EMBO Journal

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11

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12

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4261-72

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The tyrosine phosphorylated carboxyterminus of the EGF receptor is a binding site for GAP and PLC-gamma

1 reference

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Purification and characterization of phosphoinositide 3-kinase from rat liver

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Interactions of phosphatidylinositol kinase, GTPase-activating protein (GAP), and GAP-associated proteins with the colony-stimulating factor 1 receptor

1 reference

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Binding of GAP to activated PDGF receptors

1 reference

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Nck, a melanoma cDNA encoding a cytoplasmic protein consisting of the src homology units SH2 and SH3

1 reference

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1 reference

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Tyrosine mutations within the alpha platelet-derived growth factor receptor kinase insert domain abrogate receptor-associated phosphatidylinositol-3 kinase activity without affecting mitogenic or chemotactic signal transduction

1 reference

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GTPase-activating protein and phosphatidylinositol 3-kinase bind to distinct regions of the platelet-derived growth factor receptor beta subunit

1 reference

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Phosphorylation sites in the PDGF receptor with different specificities for binding GAP and PI3 kinase in vivo

1 reference

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Crystal Structure of the Catalytic Subunit of Cyclic Adenosine Monophosphate-Dependent Protein Kinase

1 reference

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Signal transduction by receptors with tyrosine kinase activity

1 reference

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1 reference

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SH2 and SH3 domains: elements that control interactions of cytoplasmic signaling proteins

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Chemical and biological evolution of nucleotide-binding protein

1 reference

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1 reference

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Alternative splicing of RNAs transcribed from the human abl gene and from the bcr-abl fused gene

1 reference

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Structural organization of the bcr gene and its role in the Ph' translocation

1 reference

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Autophosphorylation of the PDGF receptor in the kinase insert region regulates interactions with cell proteins

1 reference

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A novel viral oncogene with structural similarity to phospholipase C

1 reference

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19 March 2017

Binding of SH2 domains of phospholipase C gamma 1, GAP, and Src to activated growth factor receptors

1 reference

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19 March 2017

Patterns of divergence in homologous proteins as indicators of secondary and tertiary structure: a prediction of the structure of the catalytic domain of protein kinases

1 reference

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19 March 2017

Distinct phosphotyrosines on a growth factor receptor bind to specific molecules that mediate different signaling pathways

1 reference

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19 March 2017

A second type of rat phosphoinositide-specific phospholipase C containing a src-related sequence not essential for phosphoinositide-hydrolyzing activity

1 reference

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Role of phosphatidylinositol kinase in PDGF receptor signal transduction

1 reference

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Oncogenes and signal transduction

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Amino acid preferences for specific locations at the ends of alpha helices

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Structure of the guanine-nucleotide-binding domain of the Ha-ras oncogene product p21 in the triphosphate conformation

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Structure of a peptide inhibitor bound to the catalytic subunit of cyclic adenosine monophosphate-dependent protein kinase

1 reference

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7 April 2017

Characterization of two 85 kd proteins that associate with receptor tyrosine kinases, middle-T/pp60c-src complexes, and PI3-kinase

1 reference

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Structure and sequence of the cellular gene homologous to the RSV src gene and the mechanism for generating the transforming virus

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Autophosphorylation sites on the epidermal growth factor receptor.

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The influence of nearest-neighbor amino acids on the conformation of the middle amino acid in proteins: comparison of predicted and experimental determination of -sheets in concanavalin A.

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Secondary structure of proteins through circular dichroism spectroscopy

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Non-catalytic domains of cytoplasmic protein-tyrosine kinases: regulatory elements in signal transduction

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Epidermal growth factor binding induces a conformational change in the external domain of its receptor

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Src homology region 2 domains direct protein-protein interactions in signal transduction

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inferred from PubMed ID database lookup

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12 December 2020

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based on heuristic

inferred from PubMed ID database lookup

Algorithms for prediction of alpha-helical and beta-structural regions in globular proteins

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Amino acid distribution in protein secondary structures

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fluorescence studies of structural fluctuations in macromolecules as observed by fluorescence spectroscopy in the time, lifetime, and frequency domains

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Snake toxin secondary structure predictions. Structure activity relationships

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Second-derivative spectroscopy of proteins. A method for the quantitative determination of aromatic amino acids in proteins

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based on heuristic

inferred from PubMed ID database lookup

Hydrodynamic properties of a rigid molecule: rotational and linear diffusion and fluorescence anisotropy

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1002/J.1460-2075.1992.TB05524.X

1 reference

National Center for Biotechnology Information

PubMed publication ID

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=1330535

14 September 2022

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