(Q24337642)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16716898%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

title

Early thymic T cell development in young transgenic mice overexpressing human Cu/Zn superoxide dismutase, a model of Down syndrome (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16716898%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

main subject

superoxide dismutase 1

1 reference

GOA release 2020-03-11

thymus development

1 reference

GOA release 2020-03-11

1 reference

1 reference

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16716898%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

author name string

Julien Laurent

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16716898%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

Evelyne Paly

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16716898%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

Jacqueline London

series ordinal

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16716898%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

language of work or name

English

0 references

publication date

21 February 2006

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16716898%20AND%20SRC:MED&resulttype=core&format=json

Free Radical Biology and Medicine

28 January 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16716898%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

volume

40

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16716898%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

issue

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16716898%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

page(s)

1971-1980

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16716898%20AND%20SRC:MED&resulttype=core&format=json

Astrocytes overexpressing Cu,Zn superoxide dismutase have increased resistance to oxidative injury

28 January 2020

cites work

1 reference

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Copper/zinc superoxide dismutase transgenic brain accumulates hydrogen peroxide after perinatal hypoxia ischemia

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7 January 2021

Thymic abnormalities and enhanced apoptosis of thymocytes and bone marrow cells in transgenic mice overexpressing Cu/Zn-superoxide dismutase: implications for Down syndrome

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Copper/zinc superoxide dismutase overexpression promotes survival of cortical neurons exposed to neurotoxins in vitro

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Early steps in T cell development are affected by aging

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Partial impairment of immune functions in peripheral blood leukocytes from aged men with Down's syndrome.

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7 January 2021

The modulation of cellular susceptibility to oxidative stress: protective and destructive actions of Cu,Zn-superoxide dismutase

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7 January 2021

Overexpression of copper-zinc superoxide dismutase in trisomy 21.

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CuZn-superoxide dismutase in human thymus: immunocytochemical localisation and secretion in thymus-derived epithelial and fibroblast cell lines

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Superoxide dismutase activities of blood platelets in trisomy 21

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Alterations in thymocyte subpopulations in Down's syndrome (trisomy 21).

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Understanding the mechanism of the age-change of thymic function to promote T cell differentiation

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7 January 2021

Reactive oxygen species in immune responses

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7 January 2021

Regulation of T-cell apoptosis by reactive oxygen species.

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7 January 2021

Premature thymic involution, observed at the ultrastructural level, in two lineages of human-SOD-1 transgenic mice.

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7 January 2021

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7 January 2021

Effect of overexpression of human Cu/Zn-SOD on activation-induced lymphocyte proliferation and apoptosis

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7 January 2021

Regulation of thymocyte differentiation: pre-TCR signals and beta-selection

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7 January 2021

Reactive Oxygen Species Regulate Activation-Induced T Cell Apoptosis

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7 January 2021

Peptide-induced negative selection of thymocytes activates transcription of an NF-kappa B inhibitor

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7 January 2021

Molecular characterization of binding of calcium and carbohydrates by an early activation antigen of lymphocytes CD69

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7 January 2021

Longevity and the immune response

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7 January 2021

T-cell development and the CD4-CD8 lineage decision

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7 January 2021

Phenotypic identification of the subgroups of murine T-cell receptor alphabeta+ CD4+ CD8- thymocytes and its implication in the late stage of thymocyte development

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7 January 2021

Cellular mechanism of thymic involution

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7 January 2021

Oxidative modulation of nuclear factor-kappaB in human cells expressing mutant fALS-typical superoxide dismutases

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7 January 2021

Gene expression profile analysis in human T lymphocytes from patients with Down Syndrome

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7 January 2021

Proliferation, apoptosis and thymic involution.

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7 January 2021

Transgenic mice with increased Cu/Zn-superoxide dismutase activity: animal model of dosage effects in Down syndrome

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7 January 2021

A central role for thymic emigrants in peripheral T cell homeostasis

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7 January 2021

Regulation of thymocyte development through CD3. II. Expression of T cell receptor beta CD3 epsilon and maturation to the CD4+8+ stage are highly correlated in individual thymocytes

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7 January 2021

Ontogeny of the immune system: gamma/delta and alpha/beta T cells migrate from thymus to the periphery in alternating waves

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7 January 2021

Restricting Zap70 expression to CD4+CD8+ thymocytes reveals a T cell receptor-dependent proofreading mechanism controlling the completion of positive selection

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7 January 2021

A potential role for CD69 in thymocyte emigration

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7 January 2021

Differing effects of copper,zinc superoxide dismutase overexpression on neurotoxicity elicited by nitric oxide, reactive oxygen species, and excitotoxins

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7 January 2021

SOD1 down-regulates NF-kappaB and c-Myc expression in mice after transient focal cerebral ischemia

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7 January 2021

Involvement of the superoxide anion radical in the autoxidation of pyrogallol and a convenient assay for superoxide dismutase

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7 January 2021

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7 January 2021

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7 January 2021

Development of thymic microenvironments in vitro is oxygen-dependent and requires permanent presence of T-cell progenitors

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7 January 2021

Direct analysis of thymic function in children with Down's syndrome

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7 January 2021

Overexpression of copper/zinc superoxide dismutase in transgenic mice protects against neuronal cell death after transient focal ischemia by blocking activation of the Bad cell death signaling pathway.

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7 January 2021

Altered T-cell subsets and defective T-cell function in young children with Down syndrome (trisomy-21).

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7 January 2021

Early block in maturation is associated with thymic involution in mammary tumor-bearing mice

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7 January 2021

Inefficient ZAP-70 phosphorylation and decreased thymic selection in vivo result from inhibition of NF-kappaB/Rel

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7 January 2021

Regulation of thymus size by competition for stromal niches among early T cell progenitors

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7 January 2021