(Q24337847)

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Breakdown of 2-hydroxylated straight chain fatty acids via peroxisomal 2-hydroxyphytanoyl-CoA lyase: a revised pathway for the alpha-oxidation of straight chain fatty acids

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scholarly article

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Breakdown of 2-hydroxylated straight chain fatty acids via peroxisomal 2-hydroxyphytanoyl-CoA lyase: a revised pathway for the alpha-oxidation of straight chain fatty acids (English)

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2-hydroxyacyl-CoA lyase 1

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GOA release 2020-03-11

carbon-carbon lyase activity

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GOA release 2020-03-11

8

object named as

Minne Casteels

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Paul P Van Veldhoven

7

object named as

Paul P Van Veldhoven

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author name string

Veerle Foulon

1

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Mieke Sniekers

2

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Els Huysmans

3

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Stanny Asselberghs

4

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Vincent Mahieu

5

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Guy P Mannaerts

6

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language of work or name

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publication date

18 March 2005

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Journal of Biological Chemistry

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280

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11

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9802-12

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Fatty acid degradation in plants

1 reference

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Catalytic properties of rice alpha-oxygenase. A comparison with mammalian prostaglandin H synthases

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Identification of the pathway of alpha-oxidation of cerebronic acid in peroxisomes

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Production of formyl-CoA during peroxisomal alpha-oxidation of 3-methyl-branched fatty acids

1 reference

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Formation of a 2-methyl-branched fatty aldehyde during peroxisomal α-oxidation

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Purification, molecular cloning, and expression of 2-hydroxyphytanoyl-CoA lyase, a peroxisomal thiamine pyrophosphate-dependent enzyme that catalyzes the carbon-carbon bond cleavage during alpha-oxidation of 3-methyl-branched fatty acids

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Further studies on the substrate spectrum of phytanoyl-CoA hydroxylase: implications for Refsum disease?

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Utilization of sterol carrier protein-2 by phytanoyl-CoA 2-hydroxylase in the peroxisomal alpha oxidation of phytanic acid

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The human FA2H gene encodes a fatty acid 2-hydroxylase

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A mouse model for Zellweger syndrome

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Protein serine/threonine phosphatase inhibitors suppress phenobarbital-induced Cyp2b10 gene transcription in mouse primary hepatocytes

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Purification of brain peroxisomes and localization of 3-hydroxy-3-methylglutaryl coenzyme A reductase.

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Peroxisomal beta-oxidation of 2-methyl-branched acyl-CoA esters: stereospecific recognition of the 2S-methyl compounds by trihydroxycoprostanoyl-CoA oxidase and pristanoyl-CoA oxidase

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The deficient degradation of synthetic 2- and 3-methyl-branched fatty acids in fibroblasts from patients with peroxisomal disorders

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Technical Advance: a novel technique for the sensitive quantification of acyl CoA esters from plant tissues

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Pex14p is a member of the protein linkage map of Pex5p

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Identification and characterization of HAOX1, HAOX2, and HAOX3, three human peroxisomal 2-hydroxy acid oxidases

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Molecular cloning and nucleotide sequence of cDNA encoding rat kidney long-chain L-2-hydroxy acid oxidase. Expression of the catalytically active recombinant protein as a chimaera

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Very long-chain acyl-CoA synthetases. Human "bubblegum" represents a new family of proteins capable of activating very long-chain fatty acids

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New reactions in clavulanic acid biosynthesis

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Involvement of microsomal fatty aldehyde dehydrogenase in the alpha-oxidation of phytanic acid

1 reference

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Alpha-oxidation of 3-methyl-branched fatty acids: a revised pathway confined to peroxisomes

1 reference

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7 January 2021

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Alpha-oxidation of 2-hydroxystearic acid in vitro.

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Evidence for the importance of iron in the alpha-oxidation of 3-methyl-substituted fatty acids in the intact cell

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based on heuristic

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Aminotriazole is a potent inhibitor of alpha-oxidation of 3-methyl-substituted fatty acids in rat liver

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Fatty acid alpha-oxidation of tetradecylthioacetic acid and tetradecylthiopropionic acid in cucumber (Cucumis sativus)

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Activation of thiamine diphosphate in pyruvate decarboxylase from Zymomonas mobilis

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Enhanced expression of a-series gangliosides in fibroblasts of patients with peroxisome biogenesis disorders

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Accumulation of glycolipids in mutant Chinese hamster ovary cells (Z65) with defective peroxisomal assembly and comparison of the metabolic rate of glycosphingolipids between Z65 cells and wild-type CHO-K1 cells

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Do long-chain acyl-CoA synthetases regulate fatty acid entry into synthetic versus degradative pathways?

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alpha-Oxidation of 3-methyl-substituted fatty acids in rat liver. Production of formic acid instead of CO2, cofactor requirements, subcellular localization and formation of a 2-hydroxy-3-methylacyl-CoA intermediate

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based on heuristic

inferred from DOI database lookup

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10.1074/JBC.M413362200

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