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POT1 and TRF2 cooperate to maintain telomeric integrity
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scholarly article
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title
POT1 and TRF2 cooperate to maintain telomeric integrity
(English)
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main subject
cell biology
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Protection of telomeres 1
1 reference
stated in
GOA release 2020-03-11
Telomeric repeat binding factor 2
1 reference
stated in
GOA release 2020-03-11
telomere capping
1 reference
stated in
GOA release 2020-03-11
author name string
Qin Yang
series ordinal
1
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Yun-Ling Zheng
series ordinal
2
0 references
Curtis C Harris
series ordinal
3
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language of work or name
English
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publication date
February 2005
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published in
Molecular and Cellular Biology
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volume
25
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issue
3
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page(s)
1070-80
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describes a project that uses
ImageQuant
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stated in
Europe PubMed Central
retrieved
11 June 2022
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/PMC544002/fullTextXML
based on heuristic
inferred from PubMed Central ID database lookup
cites work
POT1-interacting protein PIP1: a telomere length regulator that recruits POT1 to the TIN2/TRF1 complex
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PTOP interacts with POT1 and regulates its localization to telomeres
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19 March 2017
Rescue of an hTERT mutant defective in telomere elongation by fusion with hPot1
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19 March 2017
Human POT1 facilitates telomere elongation by telomerase
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19 March 2017
POT1 as a terminal transducer of TRF1 telomere length control
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19 March 2017
Human Pot1 (protection of telomeres) protein: cytolocalization, gene structure, and alternative splicing
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Control of human telomere length by TRF1 and TRF2
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p53-mediated apoptosis is attenuated in Werner syndrome cells
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Mammalian telomeres end in a large duplex loop
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Extension of life-span by introduction of telomerase into normal human cells
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Normal human chromosomes have long G-rich telomeric overhangs at one end
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19 March 2017
Control of telomere length by the human telomeric protein TRF1
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A human telomeric protein
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DNA self-recognition in the structure of Pot1 bound to telomeric single-stranded DNA
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19 March 2017
Crystal structure of the Oxytricha nova telomere end binding protein complexed with single strand DNA
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19 March 2017
Sensing DNA damage through ATRIP recognition of RPA-ssDNA complexes
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19 March 2017
Cdc13 delivers separate complexes to the telomere for end protection and replication
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19 March 2017
TRF2 Protects Human Telomeres from End-to-End Fusions
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PubMed Central
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19 March 2017
TIN2 binds TRF1 and TRF2 simultaneously and stabilizes the TRF2 complex on telomeres
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PubMed Central
reference URL
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19 March 2017
Expression of POT1 is associated with tumor stage and telomere length in gastric carcinoma
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19 March 2017
DNA binding features of human POT1: a nonamer 5'-TAGGGTTAG-3' minimal binding site, sequence specificity, and internal binding to multimeric sites
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PubMed Central
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19 March 2017
Senescence Induced by Altered Telomere State, Not Telomere Loss
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19 March 2017
Pot1, the putative telomere end-binding protein in fission yeast and humans
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19 March 2017
The Bloom's syndrome gene product interacts with topoisomerase III
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19 March 2017
p53- and ATM-dependent apoptosis induced by telomeres lacking TRF2
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19 March 2017
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7 April 2017
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27 September 2017
Mammalian telomeres and telomerase: why they matter for cancer and aging
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27 September 2017
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27 September 2017
Molecular manifestations and molecular determinants of telomere capping
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27 September 2017
Telomere repeat binding factors: keeping the ends in check
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27 September 2017
Evidence that exposure of the telomere 3' overhang sequence induces senescence
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27 September 2017
Cooperative binding of single-stranded telomeric DNA by the Pot1 protein of Schizosaccharomyces pombe
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27 September 2017
Telomerase: a target for cancer therapeutics
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27 September 2017
Different telomere damage signaling pathways in human and mouse cells
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27 September 2017
Historical claims and current interpretations of replicative aging
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27 September 2017
Telomeres, aging and cancer: in search of a happy ending
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27 September 2017
Cdc13 prevents telomere uncapping and Rad50-dependent homologous recombination
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27 September 2017
T-loop assembly in vitro involves binding of TRF2 near the 3' telomeric overhang
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27 September 2017
The length of telomeric G-rich strand 3'-overhang measured by oligonucleotide ligation assay
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27 September 2017
The age of cancer
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27 September 2017
Why do we have linear chromosomes? A matter of Adam and Eve.
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27 September 2017
The terminal DNA structure of mammalian chromosomes
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27 September 2017
Long G tails at both ends of human chromosomes suggest a C strand degradation mechanism for telomere shortening
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27 September 2017
Cell cycle-regulated generation of single-stranded G-rich DNA in the absence of telomerase
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27 September 2017
Stringent sequence requirements for the formation of human telomeres
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27 September 2017
Chromatin structure of the molecular ends of Oxytricha macronuclear DNA: phased nucleosomes and a telomeric complex
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27 September 2017
Functional reintroduction of human telomeres into mammalian cells
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27 September 2017
Telomerase activity in human germline and embryonic tissues and cells.
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30 May 2018
Telomere dysfunction and the initiation of genome instability.
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29 November 2018
Telomerase maintains telomere structure in normal human cells.
1 reference
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PubMed Central
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29 November 2018
Telomere states and cell fates
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=544002
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29 November 2018
CELL BIOLOGY: Enhanced: Telomere Capping--One Strand Fits All
1 reference
stated in
PubMed
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https://pubmed.ncbi.nlm.nih.gov/15657433
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Erosion of the telomeric single-strand overhang at replicative senescence
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/15657433
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12 December 2020
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inferred from PubMed ID database lookup
Evidence for an alternative mechanism for maintaining telomere length in human tumors and tumor-derived cell lines
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/15657433
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12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1128/MCB.25.3.1070-1080.2005
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
3392694
OpenCitations bibliographic resource ID
3392694
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
3392694
PMCID
544002
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
3392694
PubMed ID
15657433
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
3392694
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