(Q24339564)

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Insights into the evolution of divergent nucleotide-binding mechanisms among pseudokinases revealed by crystal structures of human and mouse MLKL

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scholarly article

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Insights into the evolution of divergent nucleotide-binding mechanisms among pseudokinases revealed by crystal structures of human and mouse MLKL (English)

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crystal structure

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Mixed lineage kinase domain like pseudokinase

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GOA release 2020-03-11

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GOA release 2020-03-11

Jeffrey J Babon

object named as

Jeffrey J Babon

9

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object named as

James M Murphy

1

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object named as

John Silke

10

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author name string

Isabelle S Lucet

2

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Joanne M Hildebrand

3

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Maria C Tanzer

4

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Samuel N Young

5

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Pooja Sharma

6

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Guillaume Lessene

7

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Warren S Alexander

8

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Peter E Czabotar

11

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language of work or name

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publication date

1 February 2014

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Biochemical Journal

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457

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3

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369-77

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Mixed lineage kinase domain-like protein mediates necrosis signaling downstream of RIP3 kinase

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The pseudokinase MLKL mediates necroptosis via a molecular switch mechanism

1 reference

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Mlkl knockout mice demonstrate the indispensable role of Mlkl in necroptosis

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The mitochondrial phosphatase PGAM5 functions at the convergence point of multiple necrotic death pathways

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The protein kinase complement of the human genome

1 reference

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Integration, scaling, space-group assignment and post-refinement

1 reference

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Phasercrystallographic software

1 reference

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Features and development of Coot

1 reference

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PHENIX: a comprehensive Python-based system for macromolecular structure solution

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MolProbity: all-atom structure validation for macromolecular crystallography

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Characterisation of the First Enzymes Committed to Lysine Biosynthesis in Arabidopsis thaliana

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Structural insights into RIP3-mediated necroptotic signaling

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Activation segment dimerization: a mechanism for kinase autophosphorylation of non-consensus sites

1 reference

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Structure and functional characterization of the atypical human kinase haspin

1 reference

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Structure of the Pseudokinase VRK3 Reveals a Degraded Catalytic Site, a Highly Conserved Kinase Fold, and a Putative Regulatory Binding Site

1 reference

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Structure of the PAN3 pseudokinase reveals the basis for interactions with the PAN2 deadenylase and the GW182 proteins

1 reference

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ATP and MO25α Regulate the Conformational State of the STRADα Pseudokinase and Activation of the LKB1 Tumour Suppressor

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IRAK-M mediates Toll-like receptor/IL-1R-induced NFκB activation and cytokine production

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The protein kinase family: conserved features and deduced phylogeny of the catalytic domains

1 reference

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Surface comparison of active and inactive protein kinases identifies a conserved activation mechanism

1 reference

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CRYSOL– a Program to Evaluate X-ray Solution Scattering of Biological Macromolecules from Atomic Coordinates

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Necroptosis: the release of damage-associated molecular patterns and its physiological relevance

1 reference

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Pseudokiller, qu'est-ce que c'est?

1 reference

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More to life than death: molecular determinants of necroptotic and non-necroptotic RIP3 kinase signaling

1 reference

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Mixed lineage kinase domain-like is a key receptor interacting protein 3 downstream component of TNF-induced necrosis

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Toll-like receptor 3-mediated necrosis via TRIF, RIP3, and MLKL.

1 reference

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Emerging roles of pseudokinases

1 reference

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Dawn of the dead: protein pseudokinases signal new adventures in cell biology

1 reference

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A robust methodology to subclassify pseudokinases based on their nucleotide-binding properties

1 reference

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Suppression of cytokine signaling by SOCS3: characterization of the mode of inhibition and the basis of its specificity

1 reference

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Regulation of Janus kinases by SOCS proteins

1 reference

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The pseudokinase domain of JAK2 is a dual-specificity protein kinase that negatively regulates cytokine signaling

1 reference

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A convenient method for preparation of an engineered mouse interleukin-3 analog with high solubility and wild-type bioactivity.

1 reference

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PRIMUS: a Windows PC-based system for small-angle scattering data analysis

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Protein kinases: evolution of dynamic regulatory proteins

1 reference

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21 January 2018

Techniques to examine nucleotide binding by pseudokinases

1 reference

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21 January 2018

The conserved lysine of the catalytic domain of protein kinases is actively involved in the phosphotransfer reaction and not required for anchoring ATP

1 reference

https://api.crossref.org/works/10.1042%2FBJ20131270

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The kinase homology domain of receptor guanylyl cyclase C: ATP binding and identification of an adenine nucleotide sensitive site

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Sequential control of Toll-like receptor-dependent responses by IRAK1 and IRAK2.

1 reference

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2.2 A refined crystal structure of the catalytic subunit of cAMP-dependent protein kinase complexed with MnATP and a peptide inhibitor

1 reference

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21 January 2018

Identifiers

10.1042/BJ20131270

1 reference

Consolidated OpenCitations Corpus – April 2017

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OpenCitations bibliographic resource ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

PubMed publication ID

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Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

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