(Q24530406)

English

Characterization of the Rac-GAP (Rac-GTPase-activating protein) activity of beta2-chimaerin, a 'non-protein kinase C' phorbol ester receptor

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Characterization of the Rac-GAP (Rac-GTPase-activating protein) activity of beta2-chimaerin, a 'non-protein kinase C' phorbol ester receptor (English)

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author name string

Maria Jose Caloca

1

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HongBin Wang

2

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Marcelo G Kazanietz

3

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language of work or name

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publication date

15 October 2003

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Biochemical Journal

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375

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313-21

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Pt 2

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The extended protein kinase C superfamily

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Alpha 2-chimerin, an SH2-containing GTPase-activating protein for the ras-related protein p21rac derived by alternate splicing of the human n-chimerin gene, is selectively expressed in brain regions and testes

1 reference

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24 March 2017

Cerebellar beta 2-chimaerin, a GTPase-activating protein for p21 ras-related rac is specifically expressed in granule cells and has a unique N-terminal SH2 domain

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Identification and characterization of human beta 2-chimaerin: association with malignant transformation in astrocytoma

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24 March 2017

Bcr encodes a GTPase-activating protein for p21rac

1 reference

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24 March 2017

The small GTP-binding protein rac regulates growth factor-induced membrane ruffling

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Phosphotyrosine-dependent activation of Rac-1 GDP/GTP exchange by the vav proto-oncogene product

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24 March 2017

Chimaerins, novel non-protein kinase C phorbol ester receptors, associate with Tmp21-I (p23): evidence for a novel anchoring mechanism involving the chimaerin C1 domain

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24 March 2017

Phorbol esters and related analogs regulate the subcellular localization of beta 2-chimaerin, a non-protein kinase C phorbol ester receptor

1 reference

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24 March 2017

Beta2-chimaerin is a high affinity receptor for the phorbol ester tumor promoters

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1 reference

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24 March 2017

Phorbol esters modulate the Ras exchange factor RasGRP3

1 reference

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24 March 2017

Characterization of rac and cdc42 activation in chemoattractant-stimulated human neutrophils using a novel assay for active GTPases

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7 April 2017

An essential role for Rho, Rac, and Cdc42 GTPases in cell cycle progression through G1

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7 April 2017

Protein kinase C: structural and spatial regulation by phosphorylation, cofactors, and macromolecular interactions

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27 September 2017

Rho family proteins: coordinating cell responses

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27 September 2017

Eyes wide shut: protein kinase C isozymes are not the only receptors for the phorbol ester tumor promoters

1 reference

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ARF6 is required for growth factor- and rac-mediated membrane ruffling in macrophages at a stage distal to rac membrane targeting

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27 September 2017

New insights into the regulation of protein kinase C and novel phorbol ester receptors

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27 September 2017

Regulation of RasGRP via a phorbol ester-responsive C1 domain.

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Munc13-1 is a presynaptic phorbol ester receptor that enhances neurotransmitter release

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Invasion of T-lymphoma cells: cooperation between Rho family GTPases and lysophospholipid receptor signaling

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Platelet-derived growth factor and fibronectin-stimulated migration are differentially regulated by the Rac and extracellular signal-regulated kinase pathways.

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Taxonomy and function of C1 protein kinase C homology domains

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Protein kinase C isozymes and substrates

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Regulation of c-myc expression by PDGF through Rho GTPases.

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Oncogenic activity of Tiam1 and Rac1 in NIH3T3 cells.

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An essential role for Rac in Ras transformation

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Close similarity of baculovirus-expressed n-chimaerin and protein kinase C alpha as phorbol ester receptors.

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30 May 2018

Human brain n-chimaerin cDNA encodes a novel phorbol ester receptor

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Differential irreversible insertion of protein kinase C into phospholipid vesicles by phorbol esters and related activators

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1 reference

https://pubmed.ncbi.nlm.nih.gov/12877655

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1 reference

https://pubmed.ncbi.nlm.nih.gov/12877655

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based on heuristic

inferred from PubMed ID database lookup

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