(Q24536090)

5 July 2017

title

Heterologous expression of epothilone biosynthetic genes in Myxococcus xanthus (English)

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5 July 2017

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Bryan Julien

1

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5 July 2017

Sanjay Shah

series ordinal

2

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5 July 2017

language of work or name

English

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publication date

1 September 2002

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Antimicrobial Agents and Chemotherapy

5 July 2017

published in

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5 July 2017

volume

46

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5 July 2017

issue

9

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5 July 2017

page(s)

2772-2778

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Transfer of mobilizable plasmids to Sorangium cellulosum and evidence for their integration into the chromosome

5 July 2017

cites work

1 reference

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A new enzyme superfamily - the phosphopantetheinyl transferases

24 March 2017

1 reference

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The synthesis, discovery, and development of a highly promising class of microtubule stabilization agents: curative effects of desoxyepothilones B and F against human tumor xenografts in nude mice

24 March 2017

1 reference

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Novel features in a combined polyketide synthase/non-ribosomal peptide synthetase: the myxalamid biosynthetic gene cluster of the myxobacterium Stigmatella aurantiaca Sga15.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=127399

Spatial control of cell differentiation in Myxococcus xanthus

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=127399

New lessons for combinatorial biosynthesis from myxobacteria. The myxothiazol biosynthetic gene cluster of Stigmatella aurantiaca DW4/3-1.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=127399

Desoxyepothilone B is curative against human tumor xenografts that are refractory to paclitaxel.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=127399

Desoxyepothilone B: an efficacious microtubule-targeted antitumor agent with a promising in vivo profile relative to epothilone B.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=127399

Propionyl coenzyme A carboxylase is required for development of Myxococcus xanthus

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=127399

Clinical toxicities encountered with paclitaxel (Taxol).

27 September 2017

1 reference

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Engineered biosynthesis of a complete macrolactone in a heterologous host

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=127399

Epothilones, a new class of microtubule-stabilizing agents with a taxol-like mechanism of action.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=127399

devRS, an autoregulated and essential genetic locus for fruiting body development in Myxococcus xanthus

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=127399

A Sorangium cellulosum (myxobacterium) gene cluster for the biosynthesis of the macrolide antibiotic soraphen A: cloning, characterization, and homology to polyketide synthase genes from actinomycetes

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=127399

Molecular genetics of polyketides and its comparison to fatty acid biosynthesis

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=127399

Chromosome replication in Myxococcus xanthus

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=127399

Regulation of development in Myxococcus xanthus: effect of 3':5'-cyclic AMP, ADP, and nutrition

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=127399

Characterization of the biosynthetic gene cluster for the antifungal polyketide soraphen A from Sorangium cellulosum So ce26.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=127399

Optimizing the heterologous production of epothilone D in Myxococcus xanthus

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=127399

On the interactivity of complex synthesis and tumor pharmacology in the drug discovery process: total synthesis and comparative in vivo evaluations of the 15-aza epothilones

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=127399

Isolation and characterization of the epothilone biosynthetic gene cluster from Sorangium cellulosum

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=127399

Cloning and heterologous expression of the epothilone gene cluster.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=127399

Genetic suppression and phenotypic masking of a Myxococcus xanthus frzF- defect

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=127399

Epothilons A and B: antifungal and cytotoxic compounds from Sorangium cellulosum (Myxobacteria). Production, physico-chemical and biological properties

29 November 2018

1 reference

12 December 2020

Positive-negative KG cassettes for construction of multi-gene deletions using a single drug marker

1 reference

12 December 2020

Propionyl-CoA carboxylase of Myxococcus xanthus: catalytic properties and function in developing cells

1 reference

12 December 2020

Studies on the biosynthesis of epothilones: the biosynthetic origin of the carbon skeleton

1 reference

12 December 2020

In situ transposon replacement and isolation of a spontaneous tandem genetic duplication

1 reference

12 December 2020

Total Synthesis of(–)-Epothilone A

1 reference

Crossref

https://api.crossref.org/works/10.1128%2FAAC.46.9.2772-2778.2002

7 January 2021

inferred from DOI database lookup

Total Synthesis of(–)-Epothilone B: An Extension of the Suzuki Coupling Method and Insights into Structure–Activity Relationships of the Epothilones

1 reference

Crossref

https://api.crossref.org/works/10.1128%2FAAC.46.9.2772-2778.2002

7 January 2021

inferred from DOI database lookup

Identifiers

DOI

10.1128/AAC.46.9.2772-2778.2002

1 reference

5 July 2017

1 reference

5 July 2017

1 reference