(Q36541279)

English

The synthesis, discovery, and development of a highly promising class of microtubule stabilization agents: curative effects of desoxyepothilones B and F against human tumor xenografts in nude mice

scientific article published on July 2001

In more languages

Statements

scholarly article

1 reference

Europe PubMed Central

14 August 2017

The synthesis, discovery, and development of a highly promising class of microtubule stabilization agents: curative effects of desoxyepothilones B and F against human tumor xenografts in nude mice (English)

1 reference

Europe PubMed Central

14 August 2017

1 reference

based on heuristic

inferred from title

tumour xenograft

1 reference

based on heuristic

inferred from title

author name string

T C Chou

1

1 reference

Europe PubMed Central

14 August 2017

O A O'Connor

2

1 reference

Europe PubMed Central

14 August 2017

W P Tong

3

1 reference

Europe PubMed Central

14 August 2017

Y Guan

4

1 reference

Europe PubMed Central

14 August 2017

Z G Zhang

5

1 reference

Europe PubMed Central

14 August 2017

S J Stachel

6

1 reference

Europe PubMed Central

14 August 2017

C Lee

7

1 reference

Europe PubMed Central

14 August 2017

S J Danishefsky

8

1 reference

Europe PubMed Central

14 August 2017

language of work or name

0 references

publication date

1 July 2001

1 reference

Europe PubMed Central

14 August 2017

Proceedings of the National Academy of Sciences of the United States of America

1 reference

Europe PubMed Central

14 August 2017

98

1 reference

Europe PubMed Central

14 August 2017

8113-8118

1 reference

Europe PubMed Central

14 August 2017

14

1 reference

Europe PubMed Central

14 August 2017

Epothilones and related structures--a new class of microtubule inhibitors with potent in vivo antitumor activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=35476

30 September 2017

Laulimalide and isolaulimalide, new paclitaxel-like microtubule-stabilizing agents.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=35476

30 September 2017

Desoxyepothilone B is curative against human tumor xenografts that are refractory to paclitaxel.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=35476

30 September 2017

Desoxyepothilone B: an efficacious microtubule-targeted antitumor agent with a promising in vivo profile relative to epothilone B.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=35476

30 September 2017

Synthesis of epothilones A and B in solid and solution phase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=35476

30 September 2017

Discodermolide, a cytotoxic marine agent that stabilizes microtubules more potently than taxol

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=35476

30 September 2017

Clinical toxicities encountered with paclitaxel (Taxol).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=35476

30 September 2017

Epothilones, a new class of microtubule-stabilizing agents with a taxol-like mechanism of action.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=35476

30 September 2017

Quantitative analysis of dose-effect relationships: the combined effects of multiple drugs or enzyme inhibitors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=35476

30 September 2017

Evaluation of a soluble tetrazolium/formazan assay for cell growth and drug sensitivity in culture using human and other tumor cell lines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=35476

30 September 2017

New colorimetric cytotoxicity assay for anticancer-drug screening

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=35476

30 September 2017

Taxol: a review of its preclinical in vivo antitumor activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=35476

30 September 2017

Activities of the microtubule-stabilizing agents epothilones A and B with purified tubulin and in cells resistant to paclitaxel (Taxol(R)).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=35476

21 September 2018

Discodermolide: a new bioactive polyhydroxylated lactone from the marine sponge Discodermia dissoluta

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.131153098

21 January 2018

Total Synthesis of(–)-Epothilone A

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.131153098

21 January 2018

Total Synthesis of(–)-Epothilone B: An Extension of the Suzuki Coupling Method and Insights into Structure–Activity Relationships of the Epothilones

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.131153098

21 January 2018

En route to a plant scale synthesis of the promising antitumor agent 12,13-desoxyepothilone B

1 reference

https://pubmed.ncbi.nlm.nih.gov/11438750

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

On the total synthesis and preliminary biological evaluations of 15(R) and 15(S) aza-dEpoB: a Mitsunobu inversion at C15 in pre-epothilone fragments

1 reference

https://pubmed.ncbi.nlm.nih.gov/11438750

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Total synthesis and antitumor activity of 12,13-desoxyepothilone F: an unexpected solvolysis problem at C15, mediated by remote substitution at C21

1 reference

https://pubmed.ncbi.nlm.nih.gov/11438750

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A Novel Aldol Condensation with 2-Methyl-4-pentenal and Its Application to an Improved Total Synthesis of Epothilone B

1 reference

https://pubmed.ncbi.nlm.nih.gov/11438750

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Epothilone A and B—Novel 16-Membered Macrolides with Cytotoxic Activity: Isolation, Crystal Structure, and Conformation in Solution

1 reference

9 March 2024

https://opencitations.net/index/api/v1/citations/10.1002/ANIE.199615671

Identifiers

10.1073/PNAS.131153098

1 reference

Europe PubMed Central

14 August 2017

2001PNAS...98.8113C

0 references

1 reference

Europe PubMed Central

14 August 2017

1 reference

Europe PubMed Central

14 August 2017

ResearchGate publication ID

0 references

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