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SMUG1 is able to excise uracil from immunoglobulin genes: insight into mutation versus repair
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scholarly article
1 reference
stated in
Europe PubMed Central
PMCID
1383525
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16407970%20AND%20SRC:MED&resulttype=core&format=json
retrieved
15 January 2020
title
SMUG1 is able to excise uracil from immunoglobulin genes: insight into mutation versus repair
(English)
1 reference
stated in
Europe PubMed Central
PMCID
1383525
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16407970%20AND%20SRC:MED&resulttype=core&format=json
retrieved
15 January 2020
author
Javier M Di Noia
series ordinal
1
1 reference
stated in
Europe PubMed Central
PMCID
1383525
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16407970%20AND%20SRC:MED&resulttype=core&format=json
retrieved
15 January 2020
author name string
Cristina Rada
series ordinal
2
1 reference
stated in
Europe PubMed Central
PMCID
1383525
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16407970%20AND%20SRC:MED&resulttype=core&format=json
retrieved
15 January 2020
Michael S Neuberger
series ordinal
3
1 reference
stated in
Europe PubMed Central
PMCID
1383525
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16407970%20AND%20SRC:MED&resulttype=core&format=json
retrieved
15 January 2020
language of work or name
English
0 references
publication date
12 January 2006
1 reference
stated in
Europe PubMed Central
PMCID
1383525
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16407970%20AND%20SRC:MED&resulttype=core&format=json
retrieved
15 January 2020
published in
The EMBO Journal
1 reference
stated in
Europe PubMed Central
PMCID
1383525
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16407970%20AND%20SRC:MED&resulttype=core&format=json
retrieved
15 January 2020
volume
25
1 reference
stated in
Europe PubMed Central
PMCID
1383525
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16407970%20AND%20SRC:MED&resulttype=core&format=json
retrieved
15 January 2020
page(s)
585-595
1 reference
stated in
Europe PubMed Central
PMCID
1383525
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16407970%20AND%20SRC:MED&resulttype=core&format=json
retrieved
15 January 2020
issue
3
1 reference
stated in
Europe PubMed Central
PMCID
1383525
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16407970%20AND%20SRC:MED&resulttype=core&format=json
retrieved
15 January 2020
cites work
hUNG2 is the major repair enzyme for removal of uracil from U:A matches, U:G mismatches, and U in single-stranded DNA, with hSMUG1 as a broad specificity backup
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1383525
retrieved
24 March 2017
Definitive identification of mammalian 5-hydroxymethyluracil DNA N-glycosylase activity as SMUG1
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1383525
retrieved
24 March 2017
Post-replicative base excision repair in replication foci
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1383525
retrieved
24 March 2017
Immunity through DNA deamination
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1383525
retrieved
24 March 2017
The nature of enzymes involved in uracil-DNA repair: isoform characteristics of proteins responsible for nuclear and mitochondrial genomic integrity
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1383525
retrieved
24 March 2017
Excision of deaminated cytosine from the vertebrate genome: role of the SMUG1 uracil-DNA glycosylase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1383525
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24 March 2017
Suppression of spontaneous mutagenesis in human cells by DNA base excision-repair
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1383525
retrieved
24 March 2017
Mismatch recognition and uracil excision provide complementary paths to both Ig switching and the A/T-focused phase of somatic mutation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1383525
retrieved
24 March 2017
B cells from hyper-IgM patients carrying UNG mutations lack ability to remove uracil from ssDNA and have elevated genomic uracil
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1383525
retrieved
27 September 2017
C --> T mutagenesis and gamma-radiation sensitivity due to deficiency in the Smug1 and Ung DNA glycosylases
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1383525
retrieved
27 September 2017
Repair of U/G and U/A in DNA by UNG2-associated repair complexes takes place predominantly by short-patch repair both in proliferating and growth-arrested cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1383525
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27 September 2017
Uracil DNA glycosylase activity is dispensable for immunoglobulin class switch
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1383525
retrieved
27 September 2017
Immunoglobulin gene conversion in chicken DT40 cells largely proceeds through an abasic site intermediate generated by excision of the uracil produced by AID-mediated deoxycytidine deamination.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1383525
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27 September 2017
Uracil in DNA--occurrence, consequences and repair
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1383525
retrieved
27 September 2017
Expression of the human DNA glycosylase hSMUG1 in Trypanosoma brucei causes DNA damage and interferes with J biosynthesis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1383525
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27 September 2017
Altering the pathway of immunoglobulin hypermutation by inhibiting uracil-DNA glycosylase.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1383525
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27 September 2017
Enhanced CpG mutability and tumorigenesis in MBD4-deficient mice.
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1383525
retrieved
27 September 2017
AID is essential for immunoglobulin V gene conversion in a cultured B cell line
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1383525
retrieved
27 September 2017
Requirement of the activation-induced deaminase (AID) gene for immunoglobulin gene conversion
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1383525
retrieved
27 September 2017
Ablation of XRCC2/3 transforms immunoglobulin V gene conversion into somatic hypermutation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1383525
retrieved
27 September 2017
Uracil-DNA glycosylase (UNG)-deficient mice reveal a primary role of the enzyme during DNA replication
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1383525
retrieved
27 September 2017
Rapid methods for the analysis of immunoglobulin gene hypermutation: application to transgenic and gene targeted mice
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1383525
retrieved
27 September 2017
Uracil-DNA glycosylase inhibitor of bacteriophage PBS2: cloning and effects of expression of the inhibitor gene in Escherichia coli
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1383525
retrieved
27 September 2017
Light chain gene conversion continues at high rate in an ALV-induced cell line.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1383525
retrieved
27 September 2017
A mammalian cell line deficient in activity of the DNA repair enzyme 5-hydroxymethyluracil-DNA glycosylase is resistant to the toxic effects of the thymidine analog 5-hydroxymethyl-2'-deoxyuridine
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1383525
retrieved
27 September 2017
N-Glycosidase activity in extracts of Bacillus subtilis and its inhibition after infection with bacteriophage PBS2.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1383525
retrieved
27 September 2017
Immunoglobulin isotype switching is inhibited and somatic hypermutation perturbed in UNG-deficient mice
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1383525
retrieved
30 May 2018
Proteolytic degradation of the nuclear isoform of uracil-DNA glycosylase occurs during the S phase of the cell cycle
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1383525
retrieved
29 November 2018
Human uracil-DNA glycosylase deficiency associated with profoundly impaired immunoglobulin class-switch recombination
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1383525
retrieved
29 November 2018
Identifiers
DOI
10.1038/SJ.EMBOJ.7600939
1 reference
stated in
Europe PubMed Central
PMCID
1383525
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16407970%20AND%20SRC:MED&resulttype=core&format=json
retrieved
15 January 2020
PMCID
1383525
1 reference
stated in
Europe PubMed Central
PMCID
1383525
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16407970%20AND%20SRC:MED&resulttype=core&format=json
retrieved
15 January 2020
PubMed ID
16407970
1 reference
stated in
Europe PubMed Central
PMCID
1383525
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16407970%20AND%20SRC:MED&resulttype=core&format=json
retrieved
15 January 2020
ResearchGate publication ID
7364105
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