(Q24550974)

English

ACAT1 and ACAT2 membrane topology segregates a serine residue essential for activity to opposite sides of the endoplasmic reticulum membrane

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scholarly article

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ACAT1 and ACAT2 membrane topology segregates a serine residue essential for activity to opposite sides of the endoplasmic reticulum membrane (English)

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endoplasmic reticulum

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author name string

C W Joyce

1

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G S Shelness

2

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M A Davis

3

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R G Lee

4

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K Skinner

5

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R A Anderson

6

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L L Rudel

7

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language of work or name

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publication date

November 2000

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Molecular Biology of the Cell

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11

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11

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3675-87

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Characterization of two human genes encoding acyl coenzyme A:cholesterol acyltransferase-related enzymes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15029

24 March 2017

ACAT-2, a second mammalian acyl-CoA:cholesterol acyltransferase. Its cloning, expression, and characterization

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15029

24 March 2017

Human acyl-CoA:cholesterol acyltransferase-1 in the endoplasmic reticulum contains seven transmembrane domains

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15029

24 March 2017

Prediction of protein secondary structure at better than 70% accuracy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15029

7 April 2017

PHD: predicting one-dimensional protein structure by profile-based neural networks

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15029

7 April 2017

Massive xanthomatosis and altered composition of atherosclerotic lesions in hyperlipidemic mice lacking acyl CoA:cholesterol acyltransferase 1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15029

27 September 2017

Recombinant acyl-CoA:cholesterol acyltransferase-1 (ACAT-1) purified to essential homogeneity utilizes cholesterol in mixed micelles or in vesicles in a highly cooperative manner

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15029

27 September 2017

Identification of a form of acyl-CoA:cholesterol acyltransferase specific to liver and intestine in nonhuman primates

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15029

27 September 2017

Dissection of de novo membrane insertion activities of internal transmembrane segments of ATP-binding-cassette transporters: toward understanding topological rules for membrane assembly of polytopic membrane proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15029

27 September 2017

Hepatic origin of cholesteryl oleate in coronary artery atherosclerosis in African green monkeys. Enrichment by dietary monounsaturated fat.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15029

27 September 2017

Topology prediction for helical transmembrane proteins at 86% accuracy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15029

27 September 2017

Complementation of mutation in acyl-CoA:cholesterol acyltransferase (ACAT) fails to restore sterol regulation in ACAT-defective sterol-resistant hamster cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15029

27 September 2017

Role of insulin in hepatic fatty acid partitioning: emerging concepts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15029

27 September 2017

Transmembrane helices predicted at 95% accuracy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15029

27 September 2017

Hepatic ACAT activity in African green monkeys is highly correlated to plasma LDL cholesteryl ester enrichment and coronary artery atherosclerosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15029

27 September 2017

Regulation of apoB secretion from HepG2 cells: evidence for a critical role for cholesteryl ester synthesis in the response to a fatty acid challenge

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15029

27 September 2017

Membrane topology motifs in the SGLT cotransporter family

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15029

30 May 2018

Isolation and characterization of Chinese hamster ovary cell mutants deficient in acyl-coenzyme A:cholesterol acyltransferase activity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15029

30 May 2018

Structural requirements for membrane assembly of proteins spanning the membrane several times

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15029

30 May 2018

Nascent secretory chain binding and translocation are distinct processes: differentiation by chemical alkylation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15029

30 May 2018

A general method for rapid site-directed mutagenesis using the polymerase chain reaction.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15029

30 May 2018

Fine-tuning the topology of a polytopic membrane protein: role of positively and negatively charged amino acids.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15029

30 May 2018

Membrane topology and biogenesis of eukaryotic signal peptidase.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15029

28 November 2018

ACAT inhibitors decrease secretion of cholesteryl esters and apolipoprotein B by perfused livers of African green monkeys.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15029

28 November 2018

Preparation of microsomal membranes for cotranslational protein translocation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15029

28 November 2018

Effects of intracellular free cholesterol accumulation on macrophage viability: a model for foam cell death

1 reference

https://pubmed.ncbi.nlm.nih.gov/11071899

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

ApoB100 secretion from HepG2 cells is decreased by the ACAT inhibitor CI-1011: an effect associated with enhanced intracellular degradation of ApoB

1 reference

https://pubmed.ncbi.nlm.nih.gov/11071899

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential expression of ACAT1 and ACAT2 among cells within liver, intestine, kidney, and adrenal of nonhuman primates

1 reference

https://pubmed.ncbi.nlm.nih.gov/11071899

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Methods for the study of protein translocation across the RER membrane using the reticulocyte lysate translation system and canine pancreatic microsomal membranes

1 reference

https://pubmed.ncbi.nlm.nih.gov/11071899

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Insertion of a multispanning membrane protein occurs sequentially and requires only one signal sequence

1 reference

https://pubmed.ncbi.nlm.nih.gov/11071899

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Comparison of CI-976, an ACAT inhibitor, and selected lipid-lowering agents for antiatherosclerotic activity in iliac-femoral and thoracic aortic lesions. A biochemical, morphological, and morphometric evaluation

1 reference

https://pubmed.ncbi.nlm.nih.gov/11071899

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of acyl-CoA cholesterol O-acyltransferase reduces the cholesteryl ester enrichment of atherosclerotic lesions in the Yucatan micropig

1 reference

https://pubmed.ncbi.nlm.nih.gov/11071899

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of hepatic ACAT decreases ApoB secretion in miniature pigs fed a cholesterol-free diet

1 reference

https://pubmed.ncbi.nlm.nih.gov/11071899

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Topological rules for membrane protein assembly in eukaryotic cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/11071899

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1091/MBC.11.11.3675

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release_kkhut36u25brhb6xspzs3ma3im

1 reference

https://api.fatcat.wiki/v0/release/kkhut36u25brhb6xspzs3ma3im

24 November 2022

based on heuristic

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