(Q24554345)

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RWJ-54428 (MC-02,479), a new cephalosporin with high affinity for penicillin-binding proteins, including PBP 2a, and stability to staphylococcal beta-lactamases

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RWJ-54428 (MC-02,479), a new cephalosporin with high affinity for penicillin-binding proteins, including PBP 2a, and stability to staphylococcal beta-lactamases (English)

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Francois Malouin

1

object named as

Francois Malouin

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author name string

Johanne Blais

2

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Suzanne Chamberland

3

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Monica Hoang

4

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Craig Park

5

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Christin Chan

6

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Kristina Mathias

7

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Samia Hakem

8

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Kelly Dupree

9

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Eric Liu

10

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Tien Nguyen

11

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Michael N Dudley

12

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language of work or name

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publication date

February 2003

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Antimicrobial Agents and Chemotherapy

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47

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2

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658-64

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STUDIES ON THE CHEMICAL NATURE OF THE SUBSTANCE INDUCING TRANSFORMATION OF PNEUMOCOCCAL TYPES: INDUCTION OF TRANSFORMATION BY A DESOXYRIBONUCLEIC ACID FRACTION ISOLATED FROM PNEUMOCOCCUS TYPE III

1 reference

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24 March 2017

In vitro and in vivo properties of Ro 63-9141, a novel broad-spectrum cephalosporin with activity against methicillin-resistant staphylococci

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151748

24 March 2017

A functional classification scheme for beta-lactamases and its correlation with molecular structure

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24 March 2017

Low-affinity penicillin-binding protein associated with beta-lactam resistance in Staphylococcus aureus

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24 March 2017

Penicillin-binding protein-mediated resistance in pneumococci and staphylococci

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24 March 2017

In vitro activities of RWJ-54428 (MC-02,479) against multiresistant gram-positive bacteria

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27 September 2017

Recruitment of the mecA gene homologue of Staphylococcus sciuri into a resistance determinant and expression of the resistant phenotype in Staphylococcus aureus.

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27 September 2017

In vitro activities of novel trans-3,5-disubstituted pyrrolidinylthio-1beta-methylcarbapenems with potent activities against methicillin-resistant Staphylococcus aureus and Pseudomonas aeruginosa

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In vitro and in vivo antibacterial activities of OPC-20011, a novel parenteral broad-spectrum 2-oxaisocephem antibiotic.

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Bacterial pathogens isolated from patients with bloodstream infection: frequencies of occurrence and antimicrobial susceptibility patterns from the SENTRY antimicrobial surveillance program (United States and Canada, 1997).

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Epidemiology, laboratory detection, and therapy of penicillin-resistant streptococcal infections

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Methicillin resistance in staphylococci: molecular and biochemical basis and clinical implications.

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Structure of the low-affinity penicillin-binding protein 5 PBP5fm in wild-type and highly penicillin-resistant strains of Enterococcus faecium

1 reference

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27 September 2017

Use of biotinylated beta-lactams and chemiluminescence for study and purification of penicillin-binding proteins in bacteria

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27 September 2017

Identification of a streptococcal penicillin-binding protein that reacts very slowly with penicillin.

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27 September 2017

Use of extracts versus whole-cell bacterial suspensions in the identification of Staphylococcus aureus beta-lactamase variants

1 reference

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Purification of Staphylococcus aureus beta-lactamases by using sequential cation-exchange and affinity chromatography

1 reference

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New mechanisms of bacterial resistance to antimicrobial agents

1 reference

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27 September 2017

The Enterococcus hirae R40 penicillin-binding protein 5 and the methicillin-resistant Staphylococcus aureus penicillin-binding protein 2' are similar.

1 reference

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27 September 2017

Characterization of four beta-lactamases produced by Staphylococcus aureus

1 reference

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27 September 2017

Genetic relationships of penicillin-susceptible and -resistant Streptococcus pneumoniae strains isolated on different continents

1 reference

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27 September 2017

Effect of inoculum and of beta-lactamase on the anti-staphylococcal activity of thirteen penicillins and cephalosporins

1 reference

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27 September 2017

Beta-Lactam antibiotic resistance in gram-positive bacterial pathogens of the upper respiratory tract: a brief overview of mechanisms

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Penicillin-binding protein 2a from methicillin-resistant Staphylococcus aureus: kinetic characterization of its interactions with beta-lactams using electrospray mass spectrometry.

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30 May 2018

Identification of the active site serine of penicillin-binding protein 2a from methicillin-resistant Staphylococcus aureus by electrospray mass spectrometry.

1 reference

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Diversity among multidrug-resistant enterococci

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The vanB gene of vancomycin-resistant Enterococcus faecalis V583 is structurally related to genes encoding D-Ala:D-Ala ligases and glycopeptide-resistance proteins VanA and VanC.

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Purification, properties, and kinetics of enzymatic acylation with beta-lactams of soluble penicillin-binding protein 2a. A major factor in methicillin-resistant Staphylococcus aureus.

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Transferable beta-lactamase. A new mechanism for in vitro penicillin resistance in Streptococcus faecalis

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Resistance to antibiotics at medical centres in different parts of the world.

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Evidence for clonal spread of a single strain of beta-lactamase-producing Enterococcus (Streptococcus) faecalis to six hospitals in five states

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30 May 2018

Antigenic Variation of Penicillin-Binding Proteins from Penicillin-Resistant Clinical Strains of Streptococcus pneumoniae

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30 May 2018

Discovery of RWJ-54428 (MC-02,479), a new cephalosporin active against resistant gram-positive bacteria.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151748

28 November 2018

Bacterial pathogens isolated from patients with skin and soft tissue infections: frequency of occurrence and antimicrobial susceptibility patterns from the SENTRY Antimicrobial Surveillance Program (United States and Canada, 1997). SENTRY Study Grou

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Resistant penicillin-binding proteins

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Penicillin-binding proteins as resistance determinants in clinical isolates of Streptococcus pneumoniae

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Binding of beta-lactam antibiotics to penicillin-binding proteins in methicillin-resistant Staphylococcus aureus.

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

5-Fluorocytosine in human cryptococcosis

1 reference

https://api.crossref.org/works/10.1128%2FAAC.47.2.658-664.2003

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1128/AAC.47.2.658-664.2003

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