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Ras-specific exchange factor GRF: oligomerization through its Dbl homology domain and calcium-dependent activation of Raf
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scholarly article
1 reference
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PubMed
PubMed ID
10373510
retrieved
15 November 2016
title
Ras-specific exchange factor GRF: oligomerization through its Dbl homology domain and calcium-dependent activation of Raf.
(English)
1 reference
stated in
PubMed
PubMed ID
10373510
retrieved
15 November 2016
author name string
P H Anborgh
series ordinal
1
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X Qian
series ordinal
2
0 references
A G Papageorge
series ordinal
3
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W C Vass
series ordinal
4
0 references
J E DeClue
series ordinal
5
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D R Lowy
series ordinal
6
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language of work or name
English
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publication date
July 1999
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published in
Molecular and Cellular Biology
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volume
19
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page(s)
4611-22
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issue
7
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describes a project that uses
ImageQuant
1 reference
stated in
Europe PubMed Central
retrieved
11 June 2022
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/PMC84259/fullTextXML
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inferred from PubMed Central ID database lookup
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Cloning and characterization of Ras-GRF2, a novel guanine nucleotide exchange factor for Ras
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Identification of a human guanine nucleotide-releasing factor (H-GRF55) specific for Ras proteins
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A dimeric 14-3-3 protein is an essential cofactor for Raf kinase activity
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Cellular transformation and guanine nucleotide exchange activity are catalyzed by a common domain on the dbl oncogene product
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The protein kinase Pak3 positively regulates Raf-1 activity through phosphorylation of serine 338
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Rho GTPases and signaling networks
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The N-terminal pleckstrin, coiled-coil, and IQ domains of the exchange factor Ras-GRF act cooperatively to facilitate activation by calcium
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Ras recruits Raf-1 to the plasma membrane for activation by tyrosine phosphorylation
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Molecular cloning of cDNAs encoding a guanine-nucleotide-releasing factor for Ras p21
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Regulation of RasGRP via a phorbol ester-responsive C1 domain.
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The exchange factor Ras-GRF2 activates Ras-dependent and Rac-dependent mitogen-activated protein kinase pathways
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Calmodulin modulates mitogen-activated protein kinase activation in response to membrane depolarization in PC12 cells
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Critical tyrosine residues regulate the enzymatic and biological activity of Raf-1 kinase
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27 September 2017
The bovine papillomavirus E5 oncogene can cooperate with ras: identification of p21 amino acids critical for transformation by c-rasH but not v-rasH.
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27 September 2017
Identification of murine homologues of the Drosophila son of sevenless gene: potential activators of ras
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Isolation of multiple mouse cDNAs with coding homology to Saccharomyces cerevisiae CDC25: identification of a region related to Bcr, Vav, Dbl and CDC24
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27 September 2017
Oligomerization activates c-Raf-1 through a Ras-dependent mechanism
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27 September 2017
Guanine nucleotide exchange factors for the Rho GTPases: a role in human disease?
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27 September 2017
Expression of alternative forms of Ras exchange factors GRF and SOS1 in different human tissues and cell lines
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27 September 2017
Expression of two different products of CDC25Mm, a mammalian Ras activator, during development of mouse brain
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27 September 2017
Calcium activation of Ras mediated by neuronal exchange factor Ras-GRF.
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27 September 2017
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Ras1 and a putative guanine nucleotide exchange factor perform crucial steps in signaling by the sevenless protein tyrosine kinase.
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The N-terminal moiety of CDC25(Mm), a GDP/GTP exchange factor of Ras proteins, controls the activity of the catalytic domain. Modulation by calmodulin and calpain.
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28 November 2018
The Ras Guanine nucleotide Exchange Factor CDC25Mm is present at the synaptic junction.
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Identification of Grf1 on mouse chromosome 9 as an imprinted gene by RLGS-M.
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Activation of the exchange factor Ras-GRF by calcium requires an intact Dbl homology domain
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/10373510
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Binding of G protein beta gamma-subunits to pleckstrin homology domains
1 reference
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PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/10373510
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12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Characterization of mammalian C-CDC25Mm exchange factor and kinetic properties of the exchange reaction intermediate p21.C-CDC25Mm
1 reference
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PubMed
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https://pubmed.ncbi.nlm.nih.gov/10373510
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Calcium influx induces neurite growth through a Src-Ras signaling cassette
1 reference
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PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/10373510
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1128/MCB.19.7.4611
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PMCID
84259
1 reference
stated in
PubMed
PubMed ID
10373510
retrieved
15 November 2016
PubMed ID
10373510
1 reference
stated in
PubMed
PubMed ID
10373510
retrieved
15 November 2016
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