(Q28257295)

Europe PubMed Central

1 reference

7 January 2021

The GTPase superfamily: conserved structure and molecular mechanism

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7 January 2021

The GTPase superfamily: a conserved switch for diverse cell functions

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7 January 2021

Regulators and Effectors of ras Proteins

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7 January 2021

The ras superfamily of GTP-binding proteins: guidelines on nomenclature

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7 January 2021

Bcl-2 associates with the ras-related protein R-ras p23

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7 January 2021

The small GTP-binding protein rac regulates growth factor-induced membrane ruffling

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7 January 2021

The small GTP-binding protein rho regulates the assembly of focal adhesions and actin stress fibers in response to growth factors

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7 January 2021

The biochemical basis of the NADPH oxidase of phagocytes.

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7 January 2021

Vesicle-mediated protein sorting

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7 January 2021

Checkpoint controls that couple mitosis to completion of DNA replication

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7 January 2021

ADP-ribosylation factor, a small GTP-binding protein, is required for binding of the coatomer protein beta-COP to Golgi membranes

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7 January 2021

Intravesicular acidification correlates with binding of ADP-ribosylation factor to microsomal membranes

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7 January 2021

The GTP-binding protein Ran/TC4 is required for protein import into the nucleus

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7 January 2021

The binding of AP-1 clathrin adaptor particles to Golgi membranes requires ADP-ribosylation factor, a small GTP-binding protein

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7 January 2021

Influence of guanine nucleotides on complex formation between Ras and CDC25 proteins

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7 January 2021

The Saccharomyces cerevisiae CDC25 gene product binds specifically to catalytically inactive ras proteins in vivo

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7 January 2021

A stimulatory GDP/GTP exchange protein for smg p21 is active on the post-translationally processed form of c-Ki-ras p21 and rhoA p21.

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7 January 2021

RAS residues that are distant from the GDP binding site play a critical role in dissociation factor-stimulated release of GDP

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7 January 2021

The bovine papillomavirus E5 oncogene can cooperate with ras: identification of p21 amino acids critical for transformation by c-rasH but not v-rasH.

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7 January 2021

Guanine-nucleotide-releasing factor hSos1 binds to Grb2 and links receptor tyrosine kinases to Ras signalling

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7 January 2021

The SH2 and SH3 domains of mammalian Grb2 couple the EGF receptor to the Ras activator mSos1

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7 January 2021

A Drosophila SH2-SH3 adaptor protein implicated in coupling the sevenless tyrosine kinase to an activator of Ras guanine nucleotide exchange, Sos.

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7 January 2021

Binding of the Ras activator son of sevenless to insulin receptor substrate-1 signaling complexes

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7 January 2021

The function of GRB2 in linking the insulin receptor to Ras signaling pathways

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7 January 2021

Identification of murine homologues of the Drosophila son of sevenless gene: potential activators of ras

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7 January 2021

Development of cell polarity in budding yeast

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7 January 2021

BUD2 encodes a GTPase-activating protein for Bud1/Rsr1 necessary for proper bud-site selection in yeast

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7 January 2021

Functional cloning of BUD5, a CDC25-related gene from S. cerevisiae that can suppress a dominant-negative RAS2 mutant

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7 January 2021

Normal and oncogenic p21ras proteins bind to the amino-terminal regulatory domain of c-Raf-1

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7 January 2021

Complex formation between RAS and RAF and other protein kinases

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7 January 2021

Direct interaction of Ras and the amino-terminal region of Raf-1 in vitro

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7 January 2021

Mammalian Ras interacts directly with the serine/threonine kinase Raf

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7 January 2021

Catalysis of guanine nucleotide exchange on the CDC42Hs protein by the dbl oncogene product

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7 January 2021

Oncogene ect2 is related to regulators of small GTP-binding proteins

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7 January 2021

Molecular cloning and expression of the major protein kinase C substrate of platelets

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7 January 2021

Molecular analysis of pleckstrin: the major protein kinase C substrate of platelets

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7 January 2021

The PH domain: a common piece in the structural patchwork of signalling proteins

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7 January 2021

Isolation and characterization of the active cDNA of the human cell cycle gene (RCC1) involved in the regulation of onset of chromosome condensation

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7 January 2021

Mitotic regulator protein RCC1 is complexed with a nuclear ras-related polypeptide

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7 January 2021

Premature chromosome condensation is induced by a point mutation in the hamster RCC1 gene

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7 January 2021

Characterization of a guanine nucleotide-releasing factor and a GTPase-activating protein that are specific for the ras-related protein p25rab3A

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7 January 2021

DSS4-1 is a dominant suppressor of sec4-8 that encodes a nucleotide exchange protein that aids Sec4p function

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7 January 2021

A mammalian guanine-nucleotide-releasing protein enhances function of yeast secretory protein Sec4.

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7 January 2021

Molecular cloning of the cDNA for stimulatory GDP/GTP exchange protein for smg p21s (ras p21-like small GTP-binding proteins) and characterization of stimulatory GDP/GTP exchange protein

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7 January 2021

Both stimulatory and inhibitory exchange proteins, smg GDS and rho GDI, are active on multiple small GTP-binding proteins

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7 January 2021

Tissue distribution of smg p25A, a ras p21-like GTP-binding protein, studied by use of a specific monoclonal antibody

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7 January 2021

A Drosophila homolog of bovine smg p25a GDP dissociation inhibitor undergoes a shift in isoelectric point in the developmental mutant quartet

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7 January 2021

MRS6--yeast homologue of the choroideraemia gene

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7 January 2021

Purification of component A of Rab geranylgeranyl transferase: possible identity with the choroideremia gene product

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7 January 2021

Rabbit intestine contains a protein that inhibits the dissociation of GDP from and the subsequent binding of GTP to rhoB p20, a ras p21-like GTP-binding protein

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7 January 2021

Molecular cloning of cDNAs encoding the GAP-associated protein p190: implications for a signaling pathway from ras to the nucleus

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7 January 2021

A novel role for RhoGDI as an inhibitor of GAP proteins

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7 January 2021

A GDP dissociation inhibitor that serves as a GTPase inhibitor for the Ras-like protein CDC42Hs

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7 January 2021

A cytoplasmic protein stimulates normal N-ras p21 GTPase, but does not affect oncogenic mutants

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7 January 2021

ras and GAP--who's controlling whom?

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7 January 2021

SH2 and SH3 domains: elements that control interactions of cytoplasmic signaling proteins

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7 January 2021

A novel arachidonic acid-selective cytosolic PLA2 contains a Ca(2+)-dependent translocation domain with homology to PKC and GAP

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7 January 2021

Mutational and kinetic analyses of the GTPase-activating protein (GAP)-p21 interaction: the C-terminal domain of GAP is not sufficient for full activity

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7 January 2021

GAP domains responsible for ras p21-dependent inhibition of muscarinic atrial K+ channel currents

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7 January 2021

Identification of the SH3 Domain of GAP as an Essential Sequence for Ras-GAP-Mediated Signaling

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7 January 2021

GAPs in understanding Ras

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7 January 2021

cDNA cloning of the type 1 neurofibromatosis gene: complete sequence of the NF1 gene product

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7 January 2021

Aberrant regulation of ras proteins in malignant tumour cells from type 1 neurofibromatosis patients

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7 January 2021

Abnormal regulation of mammalian p21ras contributes to malignant tumor growth in von Recklinghausen (type 1) neurofibromatosis

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7 January 2021

Neurofibromatosis type 1 gene mutations in neuroblastoma

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7 January 2021

Somatic mutations in the neurofibromatosis 1 gene in human tumors

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7 January 2021

A putative Ras GTPase activating protein acts as a negative regulator of signaling by the Sevenless receptor tyrosine kinase

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7 January 2021

sar1, a gene from Schizosaccharomyces pombe encoding a protein that regulates ras1

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7 January 2021

Overexpression of RPI1, a novel inhibitor of the yeast Ras-cyclic AMP pathway, down-regulates normal but not mutationally activated ras function

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7 January 2021

Localization of the rap1GAP catalytic domain and sites of phosphorylation by mutational analysis

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7 January 2021

Novel human brain cDNA encoding a 34,000 Mr protein n-chimaerin, related to both the regulatory domain of protein kinase C and BCR, the product of the breakpoint cluster region gene

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7 January 2021

Characterization of two 85 kd proteins that associate with receptor tyrosine kinases, middle-T/pp60c-src complexes, and PI3-kinase

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7 January 2021

Cloning of PI3 kinase-associated p85 utilizing a novel method for expression/cloning of target proteins for receptor tyrosine kinases

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7 January 2021

Differential regulation in the avian song control circuit of an mRNA predicting a highly conserved protein related to protein kinase C and the bcr oncogene

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7 January 2021

A Drosophila rotund transcript expressed during spermatogenesis and imaginal disc morphogenesis encodes a protein which is similar to human Rac GTPase-activating (racGAP) proteins.

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7 January 2021

Identification and partial purification of GTPase-activating proteins from yeast and mammalian cells that preferentially act on Ypt1/Rab1 proteins

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7 January 2021

Hydrolysis of GTP by Sec4 protein plays an important role in vesicular transport and is stimulated by a GTPase-activating protein in Saccharomyces cerevisiae

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7 January 2021

A yeast GTPase-activating protein that interacts specifically with a member of the Ypt/Rab family

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7 January 2021

Protein isoprenylation and methylation at carboxyl-terminal cysteine residues

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7 January 2021

Protein prenylation: genes, enzymes, targets, and functions.

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7 January 2021

RAM2, an essential gene of yeast, and RAM1 encode the two polypeptide components of the farnesyltransferase that prenylates a-factor and Ras proteins

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7 January 2021

Selective inhibition of ras-dependent transformation by a farnesyltransferase inhibitor

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7 January 2021

Benzodiazepine peptidomimetics: potent inhibitors of Ras farnesylation in animal cells

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7 January 2021

cDNA cloning of component A of Rab geranylgeranyl transferase and demonstration of its role as a Rab escort protein

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7 January 2021

Dependence of Ypt1 and Sec4 membrane attachment on Bet2.

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7 January 2021

Bet2p and Mad2p are components of a prenyltransferase that adds geranylgeranyl onto Ypt1p and Sec4p

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7 January 2021

The mitotic feedback control gene MAD2 encodes the alpha-subunit of a prenyltransferase

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7 January 2021

Association between GTPase activators for Rho and Ras families

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7 January 2021

Molecular cloning of cDNAs encoding a guanine-nucleotide-releasing factor for Ras p21

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7 January 2021

Identification of a mammalian gene structurally and functionally related to the CDC25 gene of Saccharomyces cerevisiae

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7 January 2021

Ras1 and a putative guanine nucleotide exchange factor perform crucial steps in signaling by the sevenless protein tyrosine kinase.

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7 January 2021

PROSITE: a dictionary of sites and patterns in proteins

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7 January 2021

The SWISS-PROT protein sequence data bank.

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7 January 2021

dbEST--database for "expressed sequence tags"

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7 January 2021

A workbench for multiple alignment construction and analysis

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7 January 2021

Proto-vav and gene expression

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7 January 2021

Tyrosine kinase-stimulated guanine nucleotide exchange activity of Vav in T cell activation

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7 January 2021