(Q24564948)

English

EEN encodes for a member of a new family of proteins containing an Src homology 3 domain and is the third gene located on chromosome 19p13 that fuses to MLL in human leukemia

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scholarly article

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EEN encodes for a member of a new family of proteins containing an Src homology 3 domain and is the third gene located on chromosome 19p13 that fuses to MLL in human leukemia (English)

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1 reference

based on heuristic

inferred from title

1 reference

based on heuristic

inferred from title

2

object named as

C Caldas

author given names

C

author last names

Caldas

1 reference

PubMed publication ID

19 October 2023

author name string

C W So

1

author given names

C W

author last names

So

1 reference

PubMed publication ID

19 October 2023

M M Liu

3

author given names

M M

author last names

Liu

1 reference

PubMed publication ID

19 October 2023

S J Chen

4

author given names

S J

author last names

Chen

1 reference

PubMed publication ID

19 October 2023

Q H Huang

5

author given names

Q H

author last names

Huang

1 reference

PubMed publication ID

19 October 2023

L J Gu

6

author given names

L J

author last names

Gu

1 reference

PubMed publication ID

19 October 2023

M H Sham

7

author given names

M H

author last names

Sham

1 reference

PubMed publication ID

19 October 2023

L M Wiedemann

8

author given names

L M

author last names

Wiedemann

1 reference

PubMed publication ID

19 October 2023

L C Chan

9

author given names

L C

author last names

Chan

1 reference

PubMed publication ID

19 October 2023

language of work or name

0 references

publication date

18 March 1997

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Proceedings of the National Academy of Sciences of the United States of America

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94

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6

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2563-8

0 references

Cloning of ligand targets: systematic isolation of SH3 domain-containing proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=20128

24 March 2017

RIG-E, a human homolog of the murine Ly-6 family, is induced by retinoic acid during the differentiation of acute promyelocytic leukemia cell

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=20128

24 March 2017

An RNA polymerase II elongation factor encoded by the human ELL gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=20128

24 March 2017

Genes on chromosomes 4, 9, and 19 involved in 11q23 abnormalities in acute leukemia share sequence homology and/or common motifs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=20128

24 March 2017

Cloning of ELL, a gene that fuses to MLL in a t(11;19)(q23;p13.1) in acute myeloid leukemia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=20128

24 March 2017

Identification of a gene, MLL, that spans the breakpoint in 11q23 translocations associated with human leukemias

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=20128

24 March 2017

Involvement of a homolog of Drosophila trithorax by 11q23 chromosomal translocations in acute leukemias

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=20128

24 March 2017

The SH2 and SH3 domain-containing protein GRB2 links receptor tyrosine kinases to ras signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=20128

24 March 2017

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=20128

24 March 2017

https://api.crossref.org/works/10.1073/PNAS.94.6.2563

22 April 2017

Structural determinants of peptide-binding orientation and of sequence specificity in SH3 domains

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=20128

24 March 2017

Two binding orientations for peptides to the Src SH3 domain: development of a general model for SH3-ligand interactions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=20128

24 March 2017

Protein modules and signalling networks

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=20128

24 March 2017

Point mutations define a sequence flanking the AUG initiator codon that modulates translation by eukaryotic ribosomes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=20128

24 March 2017

The t(4;11) chromosome translocation of human acute leukemias fuses the ALL-1 gene, related to Drosophila trithorax, to the AF-4 gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=20128

24 March 2017

2.2 Mb of contiguous nucleotide sequence from chromosome III of C. elegans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=20128

7 April 2017

The PHD finger: implications for chromatin-mediated transcriptional regulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=20128

7 April 2017

Altered Hox expression and segmental identity in Mll-mutant mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=20128

7 April 2017

Processed pseudogenes: characteristics and evolution

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=20128

7 April 2017

Tyrosine kinases: modular signaling enzymes with tunable specificities

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=20128

27 September 2017

An Mll-AF9 fusion gene made by homologous recombination causes acute leukemia in chimeric mice: a method to create fusion oncogenes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=20128

27 September 2017

Cytogenetic heterogeneity in t(11;19) acute leukemia: clinical, hematological and cytogenetic analyses of 48 patients--updated published cases and 16 new observations.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=20128

27 September 2017

Self-fusion of the ALL1 gene. A new genetic mechanism for acute leukemia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=20128

27 September 2017

Molecular genetics of 11q23 chromosome translocations

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=20128

27 September 2017

Cloning of several species of MLL/MEN chimeric cDNAs in myeloid leukemia with t(11;19)(q23;p13.1) translocation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=20128

27 September 2017

The leukemia-associated-protein (LAP) domain, a cysteine-rich motif, is present in a wide range of proteins, including MLL, AF10, and MLLT6 proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=20128

27 September 2017

Molecular basis of 11q23 rearrangements in hematopoietic malignant proliferations.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=20128

27 September 2017

Characterization of the expressed gene and several processed pseudogenes for the mouse ribosomal protein L30 gene family

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=20128

27 September 2017

A consensus sequence for cleavage by vertebrate DNA topoisomerase II.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=20128

27 September 2017

Conserved DNA binding and self-association domains of the Drosophila zeste protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=20128

27 September 2017

A survey of expressed genes in Caenorhabditis elegans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=20128

27 September 2017

Detection of four different 11q23 chromosomal abnormalities by multiplex-PCR and fluorescence-based automatic DNA-fragment analysis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=20128

27 September 2017

Molecular analysis of the chromosomal breakpoint and fusion transcripts in the acute lymphoblastic SEM cell line with chromosomal translocation t(4;11).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=20128

27 September 2017

Incidence and characterization of MLL gene (11q23) rearrangements in acute myeloid leukemia M1 and M5.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=20128

30 May 2018

Sequence analysis of the breakpoint cluster region in the ALL-1 gene involved in acute leukemia.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=20128

30 May 2018

Human acute leukemia cell line with the t(4;11) chromosomal rearrangement exhibits B lineage and monocytic characteristics.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=20128

30 May 2018

Heterogeneity in the breakpoints of chromosome 19 among acute leukemic patients with the t(11;19)(q23;p13) translocation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=20128

30 May 2018

A trithorax-like gene is interrupted by chromosome 11q23 translocations in acute leukaemias

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=20128

30 May 2018

MLL self fusion mediated by Alu repeat homologous recombination and prognosis of AML-M4/M5 subtypes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=20128

28 November 2018

A specific deletion in the breakpoint cluster region of the ALL-1 gene is associated with acute lymphoblastic T-cell leukemias

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=20128

28 November 2018

Chromosomal translocations in human cancer.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=20128

28 November 2018

The der(11) chromosome contains the critical breakpoint junction in the 4;11, 9;11, and 11;19 translocations in acute leukemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/9122235

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Breakpoints at 11q23 in infant leukemias with the t(11;19)(q23;p13) are clustered

1 reference

https://pubmed.ncbi.nlm.nih.gov/9122235

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Detection of ALL-1/AF4 fusion transcript by reverse transcription-polymerase chain reaction for diagnosis and monitoring of acute leukemias with the t(4;11) translocation

1 reference

https://pubmed.ncbi.nlm.nih.gov/9122235

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mono Mac 6: a mature monoblastic leukemia cell line with t(9;11)(p21;q23)

1 reference

https://pubmed.ncbi.nlm.nih.gov/9122235

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Detection of HRX-FEL fusion transcripts in pre-pre-B-ALL with and without cytogenetic demonstration of t(4;11)

1 reference

https://pubmed.ncbi.nlm.nih.gov/9122235

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Detection of MLL gene rearrangements in adult acute lymphoblastic leukemia. A Cancer and Leukemia Group B study

1 reference

https://pubmed.ncbi.nlm.nih.gov/9122235

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Infant leukaemia biology, aetiology and treatment

1 reference

https://pubmed.ncbi.nlm.nih.gov/9122235

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Distribution of 11q23 breakpoints within the MLL breakpoint cluster region in de novo acute leukemia and in treatment-related acute myeloid leukemia: correlation with scaffold attachment regions and topoisomerase II consensus binding sites

1 reference

https://pubmed.ncbi.nlm.nih.gov/9122235

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1073/PNAS.94.6.2563

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1997PNAS...94.2563S

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release_ojtcfxoljvhthav322fl5af6ha

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PMC publication ID

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PubMed publication ID

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ResearchGate publication ID

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