(Q24567695)

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CPU86017, a berberine derivative, attenuates cardiac failure through normalizing calcium leakage and downregulated phospholamban and exerting antioxidant activity

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scholarly article

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CPU86017, a berberine derivative, attenuates cardiac failure through normalizing calcium leakage and downregulated phospholamban and exerting antioxidant activity (English)

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author name string

Min-you Qi

1

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Yu Feng

2

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De-zai Dai

3

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Na Li

4

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Yu-si Cheng

5

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Yin Dai

6

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language of work or name

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publication date

February 2010

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Acta Pharmacologica Sinica

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31

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2

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165-74

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Cardiac ryanodine receptor phosphorylation by CaM Kinase II: keeping the balance right

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4002834

24 March 2017

Catecholaminergic polymorphic ventricular tachycardia: electrocardiographic characteristics and optimal therapeutic strategies to prevent sudden death

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4002834

24 March 2017

Endothelin receptor antagonist CPU0213 and vitamin E reverse downregulation of FKBP12.6 and SERCA2a: a role of hyperphosphorylation of PKCepsilon

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4002834

24 March 2017

Isoproterenol disperses distribution of NADPH oxidase, MMP-9, and pPKCepsilon in the heart, which are mitigated by endothelin receptor antagonist CPU0213

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4002834

27 September 2017

Phospholemman: its role in normal cardiac physiology and potential as a druggable target in disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4002834

27 September 2017

Phospholamban phosphorylation by CaMKII under pathophysiological conditions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4002834

27 September 2017

Modulation of ryanodine receptor by luminal calcium and accessory proteins in health and cardiac disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4002834

27 September 2017

Calcium channel blockers and beta-blockers versus beta-blockers alone for preventing exercise-induced arrhythmias in catecholaminergic polymorphic ventricular tachycardia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4002834

27 September 2017

Novel targets for treating heart and muscle disease: stabilizing ryanodine receptors and preventing intracellular calcium leak

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4002834

27 September 2017

Acute beta-adrenergic overload produces myocyte damage through calcium leakage from the ryanodine receptor 2 but spares cardiac stem cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4002834

27 September 2017

Calcium signaling phenomena in heart diseases: a perspective

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4002834

27 September 2017

Novel therapy for heart failure and exercise-induced ventricular tachycardia based on 'fixing' the leak in ryanodine receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4002834

27 September 2017

CPU86017: a novel Class III antiarrhythmic agent with multiple actions at ion channels

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4002834

27 September 2017

Roles of cardiac ryanodine receptor in heart failure and sudden cardiac death.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4002834

27 September 2017

Ryanodine receptor/calcium release channel PKA phosphorylation: a critical mediator of heart failure progression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4002834

27 September 2017

Pharmacological efficacy of CPU 86017 on hypoxic pulmonary hypertension in rats: mediated by direct inhibition of calcium channels and antioxidant action, but indirect effects on the ET-1 pathway.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4002834

27 September 2017

Catecholaminergic polymorphic ventricular tachycardia: recent mechanistic insights

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4002834

27 September 2017

Calcium cycling proteins in heart failure, cardiomyopathy and arrhythmias

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4002834

27 September 2017

Cardiac ryanodine receptor function and regulation in heart disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4002834

27 September 2017

Clinical and molecular characterization of patients with catecholaminergic polymorphic ventricular tachycardia.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4002834

27 September 2017

Adenylyl cyclase type VI increases Akt activity and phospholamban phosphorylation in cardiac myocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4002834

30 May 2018

Photochemically generated cytosolic calcium pulses and their detection by fluo-3.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4002834

30 May 2018

Protein kinase A phosphorylation of the cardiac calcium release channel (ryanodine receptor) in normal and failing hearts. Role of phosphatases and response to isoproterenol

1 reference

https://api.crossref.org/works/10.1038%2FAPS.2009.180

21 January 2018

Reversal of isoproterenol-induced downregulation of phospholamban and FKBP12.6 by CPU0213-mediated antagonism of endothelin receptors

1 reference

https://api.crossref.org/works/10.1038%2FAPS.2009.180

21 January 2018

CPU 86017, p-chlorobenzyltetrahydroberberine chloride, attenuates monocrotaline-induced pulmonary hypertension by suppressing endothelin pathway

1 reference

https://api.crossref.org/works/10.1038%2FAPS.2009.180

21 January 2018

Probucol attenuates left ventricular dysfunction and remodeling in tachycardia-induced heart failure: roles of oxidative stress and inflammation

1 reference

https://api.crossref.org/works/10.1038%2FAPS.2009.180

21 January 2018

Ventricular arrhythmias following exposure of failing hearts to oxidative stress in vitro

1 reference

https://api.crossref.org/works/10.1038%2FAPS.2009.180

21 January 2018

Activation of inducible NOS in peripheral vessels and outcomes in heart failure patients

1 reference

https://api.crossref.org/works/10.1038%2FAPS.2009.180

21 January 2018

Protective effects of ascorbic acid against lead-induced apoptotic neurodegeneration in the developing rat hippocampus in vivo

1 reference

https://api.crossref.org/works/10.1038%2FAPS.2009.180

21 January 2018

Increased nitration of sarcoplasmic reticulum Ca2+-ATPase in human heart failure

1 reference

https://api.crossref.org/works/10.1038%2FAPS.2009.180

21 January 2018

Percutaneous cardiac recirculation-mediated gene transfer of an inhibitory phospholamban peptide reverses advanced heart failure in large animals

1 reference

https://api.crossref.org/works/10.1038%2FAPS.2009.180

21 January 2018

Abrupt changes in FKBP12.6 and SERCA2a expression contribute to sudden occurrence of ventricular fibrillation on reperfusion and are prevented by CPU86017.

1 reference

https://api.crossref.org/works/10.1038%2FAPS.2009.180

21 January 2018

FKBP12.6-mediated stabilization of calcium-release channel (ryanodine receptor) as a novel therapeutic strategy against heart failure

1 reference

https://api.crossref.org/works/10.1038%2FAPS.2009.180

21 January 2018

Identification of target domains of the cardiac ryanodine receptor to correct channel disorder in failing hearts

1 reference

https://api.crossref.org/works/10.1038%2FAPS.2009.180

21 January 2018

Prevention of endotoxin-induced sarcoplasmic reticulum calcium leak improves mitochondrial and myocardial dysfunction

1 reference

https://api.crossref.org/works/10.1038%2FAPS.2009.180

21 January 2018

Calcium antagonist property of CPU228, a dofetilide derivative, contributes to its low incidence of torsades de pointes in rabbits

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4002834

28 November 2018

Dispersion of ventricular mRNA of RyR2 and SERCA2 associated with arrhythmogenesis in rats.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4002834

28 November 2018

Sympathetic activation triggers ventricular arrhythmias in rat heart with chronic infarction and failure

1 reference

https://pubmed.ncbi.nlm.nih.gov/20139899

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A novel endothelin receptor antagonist CPU0213 improves diabetic cardiac insufficiency attributed to up-regulation of the expression of FKBP12.6, SERCA2a, and PLB in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/20139899

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Relation among exercise-induced ventricular arrhythmias, myocardial ischemia, and viability late after acute myocardial infarction

1 reference

https://pubmed.ncbi.nlm.nih.gov/20139899

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1038/APS.2009.180

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Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

PMC publication ID

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Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

PubMed publication ID

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Consolidated OpenCitations Corpus – April 2017

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