(Q34270987)

1 August 2017

title

Ryanodine receptor/calcium release channel PKA phosphorylation: a critical mediator of heart failure progression (English)

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1 August 2017

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1 reference

1

Xander H T Wehrens

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1 August 2017

3

Steven Reiken

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1 August 2017

Stephan E Lehnart

2

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1 August 2017

John A Vest

series ordinal

4

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1 August 2017

Anetta Wronska

series ordinal

5

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1 August 2017

Andrew R Marks

series ordinal

6

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1 August 2017

language of work or name

English

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publication date

6 January 2006

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Proceedings of the National Academy of Sciences of the United States of America

1 August 2017

published in

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1 August 2017

volume

103

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1 August 2017

issue

3

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1 August 2017

page(s)

511-518

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describes a project that uses

1 August 2017

ImageQuant

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC1334677/fullTextXML

inferred from PubMed Central ID database lookup

cites work

Phosphodiesterase 4D deficiency in the ryanodine-receptor complex promotes heart failure and arrhythmias

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1334677

Enhancing calstabin binding to ryanodine receptors improves cardiac and skeletal muscle function in heart failure

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1334677

Intracellular calcium release and cardiac disease

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1334677

Molecular determinants of altered contractility in heart failure

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1334677

Protection from cardiac arrhythmia through ryanodine receptor-stabilizing protein calstabin2.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1334677

Ca2+/calmodulin-dependent protein kinase II phosphorylation regulates the cardiac ryanodine receptor

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1334677

Calsequestrin determines the functional size and stability of cardiac intracellular calcium stores: Mechanism for hereditary arrhythmia

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1334677

FKBP12.6 deficiency and defective calcium release channel (ryanodine receptor) function linked to exercise-induced sudden cardiac death

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1334677

Modulation of the Ca(2+)-induced Ca(2+) release cascade by beta-adrenergic stimulation in rat ventricular myocytes

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1334677

Phosphorylation-dependent regulation of ryanodine receptors: a novel role for leucine/isoleucine zippers

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1334677

Cardiac intracellular calcium release channels: role in heart failure

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1334677

PKA phosphorylation dissociates FKBP12.6 from the calcium release channel (ryanodine receptor): defective regulation in failing hearts

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1334677

Calcium signalling in cardiac muscle: refractoriness revealed by coherent activation.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1334677

Targeting genes for self-excision in the germ line

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1334677

Regulation of the cardiac ryanodine receptor channel by luminal Ca2+ involves luminal Ca2+ sensing sites

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1334677

Transgenic approaches to define the functional role of dual site phospholamban phosphorylation

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1334677

beta-Adrenergic regulation of cAMP and protein phosphorylation in phospholamban-knockout mouse hearts

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1334677

Fractional SR Ca release is regulated by trigger Ca and SR Ca content in cardiac myocytes

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1334677

Alterations in intracellular calcium handling associated with the inverse force-frequency relation in human dilated cardiomyopathy

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1334677

Unique phosphorylation site on the cardiac ryanodine receptor regulates calcium channel activity.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1334677

Heart failure: a central factor in progressive mechanical and electrical cardiac dysfunction.

6 July 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0510113103

Beyond Bowditch: the convergence of cardiac chronotropy and inotropy

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0510113103

beta-Adrenergic stimulation synchronizes intracellular Ca(2+) release during excitation-contraction coupling in cardiac myocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0510113103

Modulation of excitation-contraction coupling by isoproterenol in cardiomyocytes with controlled SR Ca2+ load and Ca2+ current trigger

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0510113103

Characterization of a novel PKA phosphorylation site, serine-2030, reveals no PKA hyperphosphorylation of the cardiac ryanodine receptor in canine heart failure.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0510113103

Abnormal Ca2+ release, but normal ryanodine receptors, in canine and human heart failure

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0510113103

beta-adrenergic receptor blockers restore cardiac calcium release channel (ryanodine receptor) structure and function in heart failure

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0510113103

Propranolol prevents the development of heart failure by restoring FKBP12.6-mediated stabilization of ryanodine receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0510113103

Beta-blockers restore calcium release channel function and improve cardiac muscle performance in human heart failure.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0510113103

Stoichiometric phosphorylation of cardiac ryanodine receptor on serine 2809 by calmodulin-dependent kinase II and protein kinase A.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0510113103

Paradoxical SR Ca2+ release in guinea-pig cardiac myocytes after beta-adrenergic stimulation revealed by two-photon photolysis of caged Ca2+.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0510113103

Protein kinase A phosphorylation of the ryanodine receptor does not affect calcium sparks in mouse ventricular myocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0510113103

The force-frequency relationship is dependent on Ca(2+)-influx via L-type- and SR-Ca(2+)-channels in human heart

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0510113103

FKBP12.6-mediated stabilization of calcium-release channel (ryanodine receptor) as a novel therapeutic strategy against heart failure

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0510113103

Ca2+/calmodulin-dependent protein kinase modulates cardiac ryanodine receptor phosphorylation and sarcoplasmic reticulum Ca2+ leak in heart failure

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0510113103

Protein kinase A phosphorylation of the cardiac calcium release channel (ryanodine receptor) in normal and failing hearts. Role of phosphatases and response to isoproterenol

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1334677

Effects of rapamycin on ryanodine receptor/Ca(2+)-release channels from cardiac muscle

28 October 2018

1 reference

12 December 2020

Defective excitation-contraction coupling in experimental cardiac hypertrophy and heart failure

1 reference

12 December 2020

Altered stoichiometry of FKBP12.6 versus ryanodine receptor as a cause of abnormal Ca(2+) leak through ryanodine receptor in heart failure

1 reference

12 December 2020

Phosphorylation of the cardiac ryanodine receptor by cAMP-dependent protein kinase

1 reference

12 December 2020

Regulation of the Cardiac Ryanodine Receptor by Protein Kinase-Dependent Phosphorylation1

1 reference

12 December 2020

Contractile protein function in failing and nonfailing human myocardium

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.0510113103

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1 August 2017

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1 reference

1 August 2017

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