(Q24597952)

2

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M Bauer

3

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R Huber

4

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T Friedrich

5

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B Kröger

6

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W Höffken

7

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W Bode

Crystallographic structures of thrombin complexed with thrombin receptor peptides: existence of expected and novel binding modes

8

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language of work or name

English

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publication date

1 November 1995

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published in

The EMBO Journal

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volume

14

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issue

21

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page(s)

5149-57

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cites work

1 reference

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Three-dimensional structure of the complex between pancreatic secretory trypsin inhibitor (Kazal type) and trypsinogen at 1.8 A resolution. Structure solution, crystallographic refinement and preliminary structural interpretation

24 March 2017

1 reference

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The refined 2.2-A (0.22-nm) X-ray crystal structure of the ternary complex formed by bovine trypsinogen, valine-valine and the Arg15 analogue of bovine pancreatic trypsin inhibitor

24 March 2017

1 reference

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The refined 1.9 A crystal structure of human alpha-thrombin: interaction with D-Phe-Pro-Arg chloromethylketone and significance of the Tyr-Pro-Pro-Trp insertion segment

24 March 2017

1 reference

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The structure of a complex of recombinant hirudin and human alpha-thrombin

24 March 2017

1 reference

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Refined structure of the hirudin-thrombin complex

24 March 2017

1 reference

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Structure of the hirulog 3-thrombin complex and nature of the S' subsites of substrates and inhibitors

24 March 2017

1 reference

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The refined 1.9-Å X-ray crystal structure of d-Phe-Pro-Arg chloromethylketone-inhibited human α-thrombin: Structure analysis, overall structure, electrostatic properties, detailed active-site geometry, and structure-function relationships

24 March 2017

1 reference

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ALSCRIPT: a tool to format multiple sequence alignments

24 March 2017

1 reference

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SETOR: hardware-lighted three-dimensional solid model representations of macromolecules

24 March 2017

1 reference

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Dictionary of protein secondary structure: pattern recognition of hydrogen-bonded and geometrical features

24 March 2017

1 reference

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Improved methods for building protein models in electron density maps and the location of errors in these models

24 March 2017

1 reference

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Dissociation of heparin-dependent thrombin and factor Xa inhibitory activities of antithrombin-III by mutations in the reactive site

24 March 2017

1 reference

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A player of many parts: the spotlight falls on thrombin's structure.

27 September 2017

1 reference

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Coagulation inhibitors from blood-sucking animals. A new line of developing antithrombotic drugs.

27 September 2017

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Membrane-dependent reactions in blood coagulation: role of the vitamin K-dependent enzyme complexes

27 September 2017

1 reference

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Novel hirudin variants from the leech Hirudinaria manillensis. Amino acid sequence, cDNA cloning and genomic organization

27 September 2017

1 reference

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Glu-192----Gln substitution in thrombin mimics the catalytic switch induced by thrombomodulin

27 September 2017

1 reference

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Natural protein proteinase inhibitors and their interaction with proteinases

27 September 2017

1 reference

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Primary structure and function of novel O-glycosylated hirudins from the leech Hirudinaria manillensis

27 September 2017

1 reference

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Crystal structure of the thrombin-hirudin complex: a novel mode of serine protease inhibition

27 September 2017

1 reference

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Kinetics of the inhibition of thrombin by hirudin.

27 September 2017

1 reference

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Interaction of site specific hirudin variants with alpha-thrombin.

30 May 2018

1 reference

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Effect of thrombomodulin on the kinetics of the interaction of thrombin with substrates and inhibitors

30 May 2018

1 reference

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Effect of heparin on the glia-derived-nexin-thrombin interaction

30 May 2018

1 reference

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Structural and functional properties of human alpha-thrombin, phosphopyridoxylated alpha-thrombin, and gamma T-thrombin. Identification of lysyl residues in alpha-thrombin that are critical for heparin and fibrin(ogen) interactions

30 May 2018

1 reference

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Isolation, sequence analysis, and cloning of haemadin. An anticoagulant peptide from the Indian leech.

30 May 2018

1 reference

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A Kazal-type inhibitor with thrombin specificity from Rhodnius prolixus

28 November 2018

1 reference

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Antithrombin III mutation database: first update. For the Thrombin and its Inhibitors Subcommittee of the Scientific and Standardization Committee of the International Society on Thrombosis and Haemostasis.

28 November 2018

1 reference

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Glu192-->Gln substitution in thrombin yields an enzyme that is effectively inhibited by bovine pancreatic trypsin inhibitor and tissue factor pathway inhibitor.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=394622

Structure of the complex formed by bovine trypsin and bovine pancreatic trypsin inhibitor. II. Crystallographic refinement at 1.9 A resolution.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=394622

Thrombin-induced fibrinopeptide release from a fibrinogen variant (fibrinogen Sydney I) with an Aalpha Arg-16----His substitution

28 November 2018

1 reference

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[Biochemical and pharmacological aspects of the thrombin inhibitor hirudin]

28 November 2018

1 reference

12 December 2020

The action of thrombin on peptide p-nitroanilide substrates. Substrate selectivity and examination of hydrolysis under different reaction conditions

1 reference

12 December 2020

Amino acid sequences of ovomucoid third domain from 25 additional species of birds

1 reference

12 December 2020

Thrombin Glu-39 restricts the P'3 specificity to nonacidic residues

1 reference

12 December 2020

Refined 2.3 A X-ray crystal structure of bovine thrombin complexes formed with the benzamidine and arginine-based thrombin inhibitors NAPAP, 4-TAPAP and MQPA. A starting point for improving antithrombotics

1 reference

12 December 2020

Bothrojaracin, a new thrombin inhibitor isolated from Bothrops jararaca venom: characterization and mechanism of thrombin inhibition

1 reference

12 December 2020

Glycosaminoglycan contributions to both protein C activation and thrombin inhibition involve a common arginine-rich site in thrombin that includes residues arginine 93, 97, and 101

1 reference

12 December 2020

Crystallization, crystal structure analysis and molecular model of the third domain of Japanese quail ovomucoid, a Kazal type inhibitor

1 reference

12 December 2020

Identifiers

1998233

1 reference

Consolidated OpenCitations Corpus – April 2017

Consolidated OpenCitations Corpus – April 2017

1 reference

Consolidated OpenCitations Corpus – April 2017

1 reference