(Q24602345)

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Ablation of neuronal ceramide synthase 1 in mice decreases ganglioside levels and expression of myelin-associated glycoprotein in oligodendrocytes

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Ablation of neuronal ceramide synthase 1 in mice decreases ganglioside levels and expression of myelin-associated glycoprotein in oligodendrocytes (English)

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oligodendrocyte

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based on heuristic

inferred from title

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author name string

Christina Ginkel

1

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Dieter Hartmann

2

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Katharina vom Dorp

3

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Armin Zlomuzica

4

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Hany Farwanah

5

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Matthias Eckhardt

6

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Roger Sandhoff

7

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Joachim Degen

8

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Mariona Rabionet

9

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Ekrem Dere

10

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Peter Dörmann

11

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Konrad Sandhoff

12

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Klaus Willecke

13

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language of work or name

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publication date

7 December 2012

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Journal of Biological Chemistry

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287

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50

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41888-902

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Ceramide synthases at the centre of sphingolipid metabolism and biology

1 reference

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7 April 2017

Necessary role for the Lag1p motif in (dihydro)ceramide synthase activity

1 reference

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7 April 2017

LASS3 (longevity assurance homologue 3) is a mainly testis-specific (dihydro)ceramide synthase with relatively broad substrate specificity

1 reference

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7 April 2017

A deficiency of ceramide biosynthesis causes cerebellar purkinje cell neurodegeneration and lipofuscin accumulation

1 reference

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1 reference

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Defects in myelination, paranode organization and Purkinje cell innervation in the ether lipid-deficient mouse cerebellum

1 reference

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1 reference

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Ceramide function in the brain: when a slight tilt is enough.

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Modulation of ceramide synthase activity via dimerization

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1 reference

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A critical role for ceramide synthase 2 in liver homeostasis: I. alterations in lipid metabolic pathways

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Adult ceramide synthase 2 (CERS2)-deficient mice exhibit myelin sheath defects, cerebellar degeneration, and hepatocarcinomas

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Characterization of ceramide synthase 2: tissue distribution, substrate specificity, and inhibition by sphingosine 1-phosphate

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Cerebellum morphogenesis: the foliation pattern is orchestrated by multi-cellular anchoring centers

1 reference

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Differential expression of (dihydro)ceramide synthases in mouse brain: oligodendrocyte-specific expression of CerS2/Lass2.

1 reference

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1 reference

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Ceramides and other bioactive sphingolipid backbones in health and disease: lipidomic analysis, metabolism and roles in membrane structure, dynamics, signaling and autophagy

1 reference

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Myelin-associated glycoprotein and complementary axonal ligands, gangliosides, mediate axon stability in the CNS and PNS: neuropathology and behavioral deficits in single- and double-null mice.

1 reference

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Infantile-onset symptomatic epilepsy syndrome caused by a homozygous loss-of-function mutation of GM3 synthase.

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Myelin-associated glycoprotein (Siglec-4) expression is progressively and selectively decreased in the brains of mice lacking complex gangliosides.

1 reference

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Updates on functions of ceramide in chemotherapy-induced cell death and in multidrug resistance

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Combinatorial ganglioside biosynthesis

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Gangliosides are neuronal ligands for myelin-associated glycoprotein

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https://pubmed.ncbi.nlm.nih.gov/23074226

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12 December 2020

based on heuristic

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