(Q24611147)

2

0 references

Surendran Rajendran

3

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Yanli Yang

4

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Andre Derosier

5

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Philippe Wong Kai In

6

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Hilary Overton

7

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Kevin E B Parkes

8

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Nick Cammack

9

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Joseph A Martin

describes a project that uses

10

0 references

language of work or name

English

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publication date

1 December 2003

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published in

Nucleic Acids Research

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volume

31

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issue

23

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page(s)

6852-9

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ImageQuant

1 reference

Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC290251/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

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Solution structure of the RNase H domain of the HIV-1 reverse transcriptase in the presence of magnesium

7 April 2017

1 reference

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Divalent metal cofactor binding in the kinetic folding trajectory ofEscherichia coliribonuclease HI

7 April 2017

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Co-crystal of Escherichia coli RNase HI with Mn2+ ions reveals two divalent metals bound in the active site

7 April 2017

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Crystal structure of Escherichia coli RNase HI in complex with Mg2+ at 2.8 A resolution: proof for a single Mg(2+)-binding site

7 April 2017

1 reference

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Anti-influenza virus activities of 4-substituted 2,4-dioxobutanoic acid inhibitors

7 April 2017

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Inhibition of cap (m7GpppXm)-dependent endonuclease of influenza virus by 4-substituted 2,4-dioxobutanoic acid compounds

7 April 2017

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Crystal structures of open and closed forms of binary and ternary complexes of the large fragment of Thermus aquaticus DNA polymerase I: structural basis for nucleotide incorporation.

7 April 2017

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Structural basis for the 3'-5' exonuclease activity of Escherichia coli DNA polymerase I: a two metal ion mechanism

7 April 2017

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7 April 2017

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Use of a pharmacophore model to discover a new class of influenza endonuclease inhibitors

27 September 2017

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HIV-1 integrase and RNase H activities as therapeutic targets

27 September 2017

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Mutations in the ribonuclease H active site of HIV-RT reveal a role for this site in stabilizing enzyme-primer-template binding

27 September 2017

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Unique progressive cleavage mechanism of HIV reverse transcriptase RNase H

27 September 2017

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Localization of the active site of HIV-1 reverse transcriptase-associated RNase H domain on a DNA template using site-specific generated hydroxyl radicals

27 September 2017

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A two-metal ion mechanism operates in the hammerhead ribozyme-mediated cleavage of an RNA substrate

27 September 2017

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Helix structure and ends of RNA/DNA hybrids direct the cleavage specificity of HIV-1 reverse transcriptase RNase H.

27 September 2017

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Crystal structure of the ribonuclease H domain of HIV-1 reverse transcriptase

27 September 2017

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Interaction of HIV-1 ribonuclease H with polypurine tract containing RNA-DNA hybrids

27 September 2017

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HIV-1 RT-associated ribonuclease H displays both endonuclease and 3′----5′ exonuclease activity

27 September 2017

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Inhibition of HIV-1 ribonuclease H by a novel diketo acid, 4-[5-(benzoylamino)thien-2-yl]-2,4-dioxobutanoic acid

27 September 2017

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Catalysis by Escherichia coli ribonuclease HI is facilitated by a phosphate group of the substrate.

30 May 2018

1 reference

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Mutations within the RNase H Domain of Human Immunodeficiency Virus Type 1 Reverse Transcriptase Abolish Virus Infectivity

30 May 2018

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Metallobiochemistry of the magnesium ion. Characterization of the essential metal-binding site in Escherichia coli ribonuclease H.

30 May 2018

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Binding of metal ions toE. coli RNase HI observed by1H−15N heteronuclear 2D NMR

30 May 2018

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30 May 2018

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Influenza virus endoribonuclease

28 November 2018

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Metal ion catalysis of RNA cleavage by the influenza virus endonuclease

28 November 2018

1 reference

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Activation/attenuation model for RNase H. A one-metal mechanism with second-metal inhibition.

28 November 2018

1 reference

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Rapid purification of homodimer and heterodimer HIV-1 reverse transcriptase by metal chelate affinity chromatography.

28 November 2018

1 reference

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Thermal stability of Escherichia coli ribonuclease HI and its active site mutants in the presence and absence of the Mg2+ ion. Proposal of a novel catalytic role for Glu48

28 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/14627818

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Metal-ion stoichiometry of the HIV-1 RT ribonuclease H domain: evidence for two mutually exclusive sites leads to new mechanistic insights on metal-mediated hydrolysis in nucleic acid biochemistry

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/14627818

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1093/NAR/GKG881

1 reference

3408128

3408128

1 reference

1 reference

1 reference