(Q35739284)

10 August 2017

title

A two-metal ion mechanism operates in the hammerhead ribozyme-mediated cleavage of an RNA substrate (English)

1 reference

10 August 2017

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W B Lott

1

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10 August 2017

B W Pontius

series ordinal

2

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10 August 2017

P H von Hippel

series ordinal

3

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10 August 2017

language of work or name

English

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publication date

1 January 1998

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Proceedings of the National Academy of Sciences of the United States of America

10 August 2017

published in

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10 August 2017

volume

95

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10 August 2017

issue

2

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10 August 2017

page(s)

542-547

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Binuclear Metallohydrolases

10 August 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=18456

Effects of divalent metal ions on individual steps of the Tetrahymena ribozyme reaction

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=18456

The New World of ribozymes

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=18456

Recent solution structures of RNA and its complexes with drugs, peptides and proteins

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=18456

Role of Nd3+ and Pb2+ on the RNA cleavage reaction by a small ribozyme

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=18456

The structure, function and application of the hammerhead ribozyme

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=18456

Observations on catalysis by hammerhead ribozymes are consistent with a two-divalent-metal-ion mechanism

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=18456

Ribozymes: structure, function, and potential therapy for dominant genetic disorders

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=18456

Capturing the structure of a catalytic RNA intermediate: the hammerhead ribozyme

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=18456

Ribozymes: structure and mechanism in RNA catalysis

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=18456

Structure and function of the hammerhead ribozyme: an unfinished story

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=18456

How many catalytic RNAs? Ions and the Cheshire cat conjecture.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=18456

A general two-metal-ion mechanism for catalytic RNA

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=18456

Three-dimensional structure of a hammerhead ribozyme

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=18456

The crystal structure of an all-RNA hammerhead ribozyme: a proposed mechanism for RNA catalytic cleavage

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=18456

A comparison of the in vitro activity of DNA-armed and all-RNA hammerhead ribozymes

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=18456

Cocrystal structure of an editing complex of Klenow fragment with DNA

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=18456

Mode of action of alpha-latrotoxin: role of divalent cations in Ca2(+)-dependent and Ca2(+)-independent effects mediated by the toxin

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=18456

Structural basis for the 3'-5' exonuclease activity of Escherichia coli DNA polymerase I: a two metal ion mechanism

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=18456

Role of divalent metal ions in the hammerhead RNA cleavage reaction

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=18456

RNA catalysis by a group I ribozyme. Developing a model for transition state stabilization

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=18456

Explanation by the double-metal-ion mechanism of catalysis for the differential metal ion effects on the cleavage rates of 5'-oxy and 5'-thio substrates by a hammerhead ribozyme

27 July 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.95.2.542

Evidence for the role of solvated metal hydroxide in the hammerhead cleavage mechanism

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.95.2.542

Properties of a hammerhead ribozyme with deletion of stem II

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.95.2.542

Enzymatic synthesis of milligram quantities of ribozymes in small volumes

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/9435228

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.95.2.542

1 reference

10 August 2017

0 references

1 reference

10 August 2017

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