(Q24617529)

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Activation of NMDA receptors in the brainstem, rostral ventromedial medulla, and nucleus reticularis gigantocellularis mediates mechanical hyperalgesia produced by repeated intramuscular injections of acidic saline in rats

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Activation of NMDA receptors in the brainstem, rostral ventromedial medulla, and nucleus reticularis gigantocellularis mediates mechanical hyperalgesia produced by repeated intramuscular injections of acidic saline in rats (English)

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Kathleen Anne Sluka

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Kathleen A Sluka

3

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author name string

Luis F Da Silva

1

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Josimari M Desantana

2

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publication date

April 2010

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The Journal of Pain

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11

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4

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378-87

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Increased glutamate and decreased glycine release in the rostral ventromedial medulla during induction of a pre-clinical model of chronic widespread muscle pain

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Descending facilitatory pathways from the RVM initiate and maintain bilateral hyperalgesia after muscle insult

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Descending facilitation from the rostral ventromedial medulla maintains nerve injury-induced central sensitization

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27 September 2017

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Contributions of the medullary raphe and ventromedial reticular region to pain modulation and other homeostatic functions

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Supraspinal contributions to hyperalgesia

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Involvement of excitatory amino acid receptors and nitric oxide in the rostral ventromedial medulla in modulating secondary hyperalgesia produced by mustard oil.

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27 September 2017

Descending facilitatory influences from the rostral medial medulla mediate secondary, but not primary hyperalgesia in the rat.

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27 September 2017

Role of glutamate receptors and nitric oxide in the rostral ventromedial medulla in visceral hyperalgesia

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27 September 2017

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27 September 2017

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27 September 2017

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27 September 2017

Sensitization of pain-modulating neurons in the rostral ventromedial medulla after peripheral nerve injury.

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30 May 2018

NMDA receptor-mediated activation of medullary pro-nociceptive neurons is required for secondary thermal hyperalgesia

1 reference

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30 May 2018

Microinjection of baclofen in the ventromedial medulla of rats: antinociception at low doses and hyperalgesia at high doses

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30 May 2018

Afferent connections of the rostral medulla of the cat: a neural substrate for midbrain-medullary interactions in the modulation of pain

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Somatic sensory properties of bulbar reticular neurons

1 reference

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30 May 2018

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Effects of NMDA and non-NMDA ionotropic glutamate receptor antagonists on the development and maintenance of hyperalgesia induced by repeated intramuscular injection of acidic saline

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28 November 2018

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1 reference

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1 reference

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1 reference

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1 reference

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Evidence of a Monosynaptic Pathway Between Cells of the Ventromedial Medulla and the Motoneuron Pool of the Thoracic Spinal Cord in Rat: Electron Microscopic Analysis of Synaptic Contacts

1 reference

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1 reference

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1 reference

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10.1016/J.JPAIN.2009.08.006

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24 November 2022

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