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Lessons from the lysozyme of phage T4
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title
Lessons from the lysozyme of phage T4
(English)
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author
Brian Matthews
series ordinal
4
object named as
Brian W Matthews
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author name string
Walter A Baase
series ordinal
1
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Lijun Liu
series ordinal
2
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Dale E Tronrud
series ordinal
3
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language of work or name
English
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publication date
April 2010
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published in
Protein Science
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volume
19
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issue
4
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page(s)
631-41
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cites work
Boron Mimetics: 1,2-Dihydro-1,2-azaborines Bind inside a Nonpolar Cavity of T4 Lysozyme
1 reference
stated in
PubMed Central
reference URL
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7 April 2017
Use of stabilizing mutations to engineer a charged group within a ligand-binding hydrophobic cavity in T4 lysozyme
1 reference
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PubMed Central
reference URL
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7 April 2017
Similar Energetic Contributions of Packing in the Core of Membrane and Water-Soluble Proteins
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7 April 2017
Contributions of all 20 amino acids at site 96 to the stability and structure of T4 lysozyme
1 reference
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PubMed Central
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7 April 2017
Evaluation at atomic resolution of the role of strain in destabilizing the temperature-sensitive T4 lysozyme mutant Arg 96 → His
1 reference
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PubMed Central
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7 April 2017
Halogenated benzenes bound within a non-polar cavity in T4 lysozyme provide examples of I...S and I...Se halogen-bonding
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867005
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7 April 2017
Use of experimental crystallographic phases to examine the hydration of polar and nonpolar cavities in T4 lysozyme
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867005
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7 April 2017
Relocation or duplication of the helix A sequence of T4 lysozyme causes only modest changes in structure but can increase or decrease the rate of folding
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867005
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7 April 2017
Repacking the Core of T4 lysozyme by automated design
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867005
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7 April 2017
Minimization of cavity size ensures protein stability and folding: structures of Phe46-replaced bovine pancreatic RNase A
1 reference
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7 April 2017
A model binding site for testing scoring functions in molecular docking
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PubMed Central
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7 April 2017
Use of a non-rigid region in T4 lysozyme to design an adaptable metal-binding site
1 reference
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PubMed Central
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7 April 2017
Structural analysis of a non-contiguous second-site revertant in T4 lysozyme shows that increasing the rigidity of a protein can enhance its stability
1 reference
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PubMed Central
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7 April 2017
De novo protein design: fully automated sequence selection
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PubMed Central
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7 April 2017
Enhancement of protein stability by the combination of point mutations in T4 lysozyme is additive
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867005
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7 April 2017
Structural and energetic responses to cavity-creating mutations in hydrophobic cores: observation of a buried water molecule and the hydrophilic nature of such hydrophobic cavities
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867005
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7 April 2017
How amino-acid insertions are allowed in an alpha-helix of T4 lysozyme
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867005
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7 April 2017
A covalent enzyme-substrate intermediate with saccharide distortion in a mutant T4 lysozyme
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867005
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7 April 2017
The role of backbone flexibility in the accommodation of variants that repack the core of T4 lysozyme
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867005
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7 April 2017
A relationship between protein stability and protein function
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867005
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7 April 2017
Protein flexibility and adaptability seen in 25 crystal forms of T4 lysozyme
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867005
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7 April 2017
Specificity of ligand binding in a buried nonpolar cavity of T4 lysozyme: linkage of dynamics and structural plasticity
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867005
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7 April 2017
Enhanced protein thermostability from site-directed mutations that decrease the entropy of unfolding
1 reference
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PubMed Central
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7 April 2017
Contributions of hydrogen bonds of Thr 157 to the thermodynamic stability of phage T4 lysozyme
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867005
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7 April 2017
Large increases in general stability for subtilisin BPN' through incremental changes in the free energy of unfolding
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PubMed Central
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7 April 2017
Structural studies of mutants of T4 lysozyme that alter hydrophobic stabilization
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867005
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7 April 2017
Toward a simplification of the protein folding problem: a stabilizing polyalanine alpha-helix engineered in T4 lysozyme
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867005
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7 April 2017
Contributions of engineered surface salt bridges to the stability of T4 lysozyme determined by directed mutagenesis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867005
retrieved
7 April 2017
A cavity-containing mutant of T4 lysozyme is stabilized by buried benzene
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867005
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7 April 2017
Multiple alanine replacements within α‐helix 126–134 of T4 lysozyme have independent, additive effects on both structure and stability
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867005
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7 April 2017
Structure of a stabilizing disulfide bridge mutant that closes the active‐site cleft of T4 lysozyme
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867005
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7 April 2017
GPCR engineering yields high-resolution structural insights into beta2-adrenergic receptor function
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867005
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7 April 2017
The conformation of thermolysin
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867005
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7 April 2017
Tertiary templates for proteins. Use of packing criteria in the enumeration of allowed sequences for different structural classes
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867005
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7 April 2017
Response of a protein structure to cavity-creating mutations and its relation to the hydrophobic effect
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867005
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7 April 2017
The structure and function of G-protein-coupled receptors
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867005
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7 April 2017
Stability effects of mutations and protein evolvability
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PubMed Central
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27 September 2017
The folding pathway of T4 lysozyme: the high-resolution structure and folding of a hidden intermediate
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867005
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27 September 2017
The folding pathway of T4 lysozyme: an on-pathway hidden folding intermediate
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867005
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27 September 2017
An approach to crystallizing proteins by synthetic symmetrization
1 reference
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867005
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27 September 2017
Cooperative water filling of a nonpolar protein cavity observed by high-pressure crystallography and simulation
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27 September 2017
Studying excited states of proteins by NMR spectroscopy.
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27 September 2017
Context-dependent protein stabilization by methionine-to-leucine substitution shown in T4 lysozyme
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27 September 2017
Protein structural plasticity exemplified by insertion and deletion mutants in T4 lysozyme
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27 September 2017
Why protein crystals favour some space-groups over others
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27 September 2017
Hydrophobic core repacking and aromatic-aromatic interaction in the thermostable mutant of T4 lysozyme Ser 117-->Phe
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27 September 2017
Intramolecular cavities in globular proteins
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27 September 2017
Frameshift mutations and the genetic code. This paper is dedicated to Professor Theodosius Dobzhansky on the occasion of his 66th birthday
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27 September 2017
The Three Dimensional Structure of the Lysozyme from Bacteriophage T4
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27 September 2017
Hydrophobic packing in T4 lysozyme probed by cavity-filling mutants
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27 September 2017
Stabilization of phage T4 lysozyme by engineered disulfide bonds
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867005
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27 September 2017
Folding and function of a T4 lysozyme containing 10 consecutive alanines illustrate the redundancy of information in an amino acid sequence
1 reference
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PubMed Central
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27 September 2017
What is the average conformation of bacteriophage T4 lysozyme in solution? A domain orientation study using dipolar couplings measured by solution NMR.
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30 May 2018
The response of T4 lysozyme to large-to-small substitutions within the core and its relation to the hydrophobic effect.
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30 May 2018
Development of an in vivo method to identify mutants of phage T4 lysozyme of enhanced thermostability
1 reference
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PubMed Central
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30 May 2018
Systematic mutation of bacteriophage T4 lysozyme.
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30 May 2018
Detection and characterization of an early folding intermediate of T4 lysozyme using pulsed hydrogen exchange and two-dimensional NMR
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PubMed Central
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30 May 2018
Design and structural analysis of alternative hydrophobic core packing arrangements in bacteriophage T4 lysozyme
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30 May 2018
Slow internal dynamics in proteins: application of NMR relaxation dispersion spectroscopy to methyl groups in a cavity mutant of T4 lysozyme
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21 January 2018
Access of ligands to cavities within the core of a protein is rapid
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21 January 2018
Use of an ion-binding site to bypass the 1000-atom limit to structure determination by direct methods.
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28 November 2018
Step-wise mutation of barnase to binase. A procedure for engineering increased stability of proteins and an experimental analysis of the evolution of protein stability
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28 November 2018
Substantial increase of protein stability by multiple disulphide bonds
1 reference
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Crossref
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https://api.crossref.org/works/10.1002%2FPRO.344
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21 January 2018
Energetic origins of specificity of ligand binding in an interior nonpolar cavity of T4 lysozyme
1 reference
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PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/20095051
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Thermodynamic stability and point mutations of bacteriophage T4 lysozyme
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/20095051
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1002/PRO.344
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PMC publication ID
2867005
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PubMed publication ID
20095051
0 references
ResearchGate publication ID
41113124
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