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Direct DNA binding by Brca1
scientific article
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instance of
scholarly article
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title
Direct DNA binding by Brca1
(English)
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author name string
T T Paull
series ordinal
1
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D Cortez
series ordinal
2
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B Bowers
series ordinal
3
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S J Elledge
series ordinal
4
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M Gellert
series ordinal
5
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language of work or name
English
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publication date
22 May 2001
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published in
Proceedings of the National Academy of Sciences of the United States of America
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volume
98
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page(s)
6086-91
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issue
11
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cites work
BRCA1 is associated with a human SWI/SNF-related complex: linking chromatin remodeling to breast cancer
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BASC, a super complex of BRCA1-associated proteins involved in the recognition and repair of aberrant DNA structures
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ATM phosphorylates p95/nbs1 in an S-phase checkpoint pathway
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Nbs1 potentiates ATP-driven DNA unwinding and endonuclease cleavage by the Mre11/Rad50 complex
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Mapping the functional domains of BRCA1. Interaction of the ring finger domains of BRCA1 and BARD1
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Stable interaction between the products of the BRCA1 and BRCA2 tumor suppressor genes in mitotic and meiotic cells
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The 3' to 5' exonuclease activity of Mre 11 facilitates repair of DNA double-strand breaks
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Components of the Ku-dependent non-homologous end-joining pathway are involved in telomeric length maintenance and telomeric silencing
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BRCA1 is a component of the RNA polymerase II holoenzyme
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A strong candidate for the breast and ovarian cancer susceptibility gene BRCA1
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A critical role for histone H2AX in recruitment of repair factors to nuclear foci after DNA damage
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Functional link between ataxia-telangiectasia and Nijmegen breakage syndrome gene products
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7 April 2017
Association of BRCA1 with the hRad50-hMre11-p95 complex and the DNA damage response
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7 April 2017
Targeted mutations of breast cancer susceptibility gene homologs in mice: lethal phenotypes of Brca1, Brca2, Brca1/Brca2, Brca1/p53, and Brca2/p53 nullizygous embryos
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Embryonic lethality and radiation hypersensitivity mediated by Rad51 in mice lacking Brca2
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7 April 2017
Association of BRCA1 with Rad51 in mitotic and meiotic cells
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7 April 2017
BRCA1 is a 220-kDa nuclear phosphoprotein that is expressed and phosphorylated in a cell cycle-dependent manner
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7 April 2017
Role for ATM in DNA damage-induced phosphorylation of BRCA1
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7 April 2017
Requirement of ATM-dependent phosphorylation of brca1 in the DNA damage response to double-strand breaks
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PubMed Central
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7 April 2017
Nuclear foci of mammalian recombination proteins are located at single-stranded DNA regions formed after DNA damage
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PubMed Central
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7 April 2017
Brca1 controls homology-directed DNA repair
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PubMed Central
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Dynamic changes of BRCA1 subnuclear location and phosphorylation state are initiated by DNA damage
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7 April 2017
A mutation in mouse rad51 results in an early embryonic lethal that is suppressed by a mutation in p53
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The tumor suppressor gene Brca1 is required for embryonic cellular proliferation in the mouse
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ATM phosphorylation of Nijmegen breakage syndrome protein is required in a DNA damage response
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PubMed Central
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A mechanistic basis for Mre11-directed DNA joining at microhomologies
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The genetics of inherited breast cancer
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PubMed Central
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Role of the tumor suppressor gene Brca1 in genetic stability and mammary gland tumor formation
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=33426
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27 September 2017
BRCA1 signals ARF-dependent stabilization and coactivation of p53.
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=33426
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27 September 2017
Mre11 is essential for the maintenance of chromosomal DNA in vertebrate cells
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=33426
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27 September 2017
The Mre11-Rad50-Xrs2 protein complex facilitates homologous recombination-based double-strand break repair in Saccharomyces cerevisiae
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PubMed Central
reference URL
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27 September 2017
Induction of GADD45 and JNK/SAPK-dependent apoptosis following inducible expression of BRCA1.
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PubMed Central
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27 September 2017
Centrosome amplification and a defective G2-M cell cycle checkpoint induce genetic instability in BRCA1 exon 11 isoform-deficient cells
1 reference
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PubMed Central
reference URL
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27 September 2017
The univector plasmid-fusion system, a method for rapid construction of recombinant DNA without restriction enzymes
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=33426
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27 September 2017
BRCA1 required for transcription-coupled repair of oxidative DNA damage
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=33426
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27 September 2017
Arrest of the cell cycle by the tumour-suppressor BRCA1 requires the CDK-inhibitor p21WAF1/CiP1.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=33426
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27 September 2017
BRCA1 is a cell cycle-regulated nuclear phosphoprotein
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=33426
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27 September 2017
BRCA1 expression is induced before DNA synthesis in both normal and tumor-derived breast cells.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=33426
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27 September 2017
Inactivation of the mouse Brca1 gene leads to failure in the morphogenesis of the egg cylinder in early postimplantation development.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=33426
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27 September 2017
Brca1 deficiency results in early embryonic lethality characterized by neuroepithelial abnormalities
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=33426
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27 September 2017
Gross chromosomal rearrangements in Saccharomyces cerevisiae replication and recombination defective mutants
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30 May 2018
A targeted disruption of the murine Brca1 gene causes gamma-irradiation hypersensitivity and genetic instability.
1 reference
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Crossref
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https://api.crossref.org/works/10.1073%2FPNAS.111125998
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21 January 2018
Rotary shadowing of extended molecules dried from glycerol
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/11353843
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
The many interfaces of Mre11
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/11353843
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1073/PNAS.111125998
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
940109
ADS bibcode
2001PNAS...98.6086P
0 references
OpenCitations bibliographic resource ID
940109
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
940109
PMCID
33426
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
940109
PubMed ID
11353843
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
940109
ResearchGate publication ID
11983761
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