(Q33860834)

29 July 2017

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title

Role of the tumor suppressor gene Brca1 in genetic stability and mammary gland tumor formation (English)

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29 July 2017

Deng CX

1

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29 July 2017

Scott F

series ordinal

2

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29 July 2017

language of work or name

English

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publication date

1 February 2000

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29 July 2017

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29 July 2017

19

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29 July 2017

8

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29 July 2017

1059-1064

1 reference

https://scigraph.springernature.com/pub.10.1038/sj.onc.1203269

29 July 2017

0 references

cites work

Isolation of the mouse homologue of BRCA1 and genetic mapping to mouse chromosome 11.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203269

Double indemnity: p53, BRCA and cancer. p53 mutation partially rescues developmental arrest in Brca1 and Brca2 null mice, suggesting a role for familial breast cancer genes in DNA damage repair.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203269

Breast cancer susceptibility genes. BRCA1 and BRCA2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203269

Centrosome hyperamplification in human cancer: chromosome instability induced by p53 mutation and/or Mdm2 overexpression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203269

The second BRCT domain of BRCA1 proteins interacts with p53 and stimulates transcription from the p21WAF1/CIP1 promoter

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203269

The nuclear localization sequences of the BRCA1 protein interact with the importin-alpha subunit of the nuclear transport signal receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203269

Stable interaction between the products of the BRCA1 and BRCA2 tumor suppressor genes in mitotic and meiotic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203269

Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203269

Abnormal centrosome amplification in the absence of p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203269

BRCA1 mutations in primary breast and ovarian carcinomas.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203269

BRCA1 required for transcription-coupled repair of oxidative DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203269

Brca1 deficiency results in early embryonic lethality characterized by neuroepithelial abnormalities

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203269

Partial rescue of Brca1 (5-6) early embryonic lethality by p53 or p21 null mutation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203269

The tumor suppressor gene Brca1 is required for embryonic cellular proliferation in the mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203269

Linkage of early-onset familial breast cancer to chromosome 17q21

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203269

Induction of GADD45 and JNK/SAPK-dependent apoptosis following inducible expression of BRCA1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203269

BRCA1 is associated with the centrosome during mitosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203269

Cell cycle-dependent colocalization of BARD1 and BRCA1 proteins in discrete nuclear domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203269

Cancer-susceptibility genes. Gatekeepers and caretakers

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203269

Expression of Brca1 is associated with terminal differentiation of ectodermally and mesodermally derived tissues in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203269

A mutation in mouse rad51 results in an early embryonic lethal that is suppressed by a mutation in p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203269

Centrosome hypertrophy in human breast tumors: implications for genomic stability and cell polarity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203269

Inactivation of the mouse Brca1 gene leads to failure in the morphogenesis of the egg cylinder in early postimplantation development.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203269

Targeted mutations of breast cancer susceptibility gene homologs in mice: lethal phenotypes of Brca1, Brca2, Brca1/Brca2, Brca1/p53, and Brca2/p53 nullizygous embryos

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203269

The developmental pattern of Brca1 expression implies a role in differentiation of the breast and other tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203269

A strong candidate for the breast and ovarian cancer susceptibility gene BRCA1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203269

BRCA1 regulates p53-dependent gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203269

Involvement of Brca2 in DNA repair

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203269

BRCA1: a review of structure and putative functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203269

The spindle assembly checkpoint

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203269

BRCA1 is a cell cycle-regulated nuclear phosphoprotein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203269

Association of BRCA1 with Rad51 in mitotic and meiotic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203269

Embryonic lethality and radiation hypersensitivity mediated by Rad51 in mice lacking Brca2

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203269

A targeted disruption of the murine Brca1 gene causes gamma-irradiation hypersensitivity and genetic instability.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203269

Rad51 protein involved in repair and recombination in S. cerevisiae is a RecA-like protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203269

Arrest of the cell cycle by the tumour-suppressor BRCA1 requires the CDK-inhibitor p21WAF1/CiP1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203269

The risk of cancer associated with specific mutations of BRCA1 and BRCA2 among Ashkenazi Jews

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203269

The complete BRCA2 gene and mutations in chromosome 13q-linked kindreds

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203269

Localization of BRCA1 and a splice variant identifies the nuclear localization signal

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203269

Cre-mediated gene deletion in the mammary gland

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203269

BRCA1 proteins are transported to the nucleus in the absence of serum and splice variants BRCA1a, BRCA1b are tyrosine phosphoproteins that associate with E2F, cyclins and cyclin dependent kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203269

Differential subcellular localization, expression and biological toxicity of BRCA1 and the splice variant BRCA1-delta11b

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203269

Keeping the centrosome cycle on track. Genome stability

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203269

Identification of the breast cancer susceptibility gene BRCA2

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203269

Identification of a RING protein that can interact in vivo with the BRCA1 gene product

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203269

Distinct transcription start sites generate two forms of BRCA1 mRNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203269

Mutations of the BRCA1 gene in human cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203269

Conditional mutation of Brca1 in mammary epithelial cells results in blunted ductal morphogenesis and tumour formation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203269

Centrosome amplification and a defective G2-M cell cycle checkpoint induce genetic instability in BRCA1 exon 11 isoform-deficient cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203269

BRCA1 physically associates with p53 and stimulates its transcriptional activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203269

Tumour amplified kinase STK15/BTAK induces centrosome amplification, aneuploidy and transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203269

Transcriptional activation by BRCA1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203269

21 January 2018

Branching out with BRCA1

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203269

inferred from DOI database lookup

7 January 2021

based on heuristic

p53 involvement in BRCA1-associated breast cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203269

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/SJ.ONC.1203269

1 reference

Dimensions Publication ID

29 July 2017

1027659434

0 references

Fatcat ID

release_7zlqynmssjfsjf7v63r37s26vy

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/7zlqynmssjfsjf7v63r37s26vy

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference