(Q24633183)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20686566%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

title

From noncoding variant to phenotype via SORT1 at the 1p13 cholesterol locus (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20686566%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

1 reference

Ludmila Prokunina-Olsson

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20686566%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

Vera M Ruda

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20686566%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

Michael C. Phillips

18

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20686566%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

Kenechi G. Ejebe

22

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20686566%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

Marju Orho-Melander

23

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20686566%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

Victor E. Koteliansky

25

object named as

Victor Koteliansky

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20686566%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

24

Olle Melander

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20686566%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

15

Eric E Schadt

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20686566%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

28

Chad A Cowan

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20686566%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

11

James P Pirruccello

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20686566%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

30

Daniel J Rader

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20686566%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

1

Kiran Musunuru

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20686566%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

12

Brian Muchmore

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20686566%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

author name string

Alanna Strong

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20686566%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

Maria Frank-Kamenetsky

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20686566%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

Noemi E Lee

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20686566%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

Tim Ahfeldt

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20686566%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

Katherine V Sachs

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20686566%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

Xiaoyu Li

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20686566%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

Hui Li

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20686566%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

Nicolas Kuperwasser

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20686566%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

Jennifer L Hall

14

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20686566%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

Carlos R Morales

16

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20686566%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

Sissel Lund-Katz

17

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20686566%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

Jamie Wong

19

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20686566%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

William Cantley

20

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20686566%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

Timothy Racie

21

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20686566%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

Kevin Fitzgerald

26

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20686566%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

Ronald M Krauss

27

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20686566%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

Sekar Kathiresan

29

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20686566%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

language of work or name

English

0 references

publication date

1 August 2010

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20686566%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20686566%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

volume

466

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20686566%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

issue

7307

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20686566%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

page(s)

714-719

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20686566%20AND%20SRC:MED&resulttype=core&format=json

Biological, clinical and population relevance of 95 loci for blood lipids

9 February 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3062476

Genome-wide association of early-onset myocardial infarction with single nucleotide polymorphisms and copy number variants

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3062476

Genome-wide association analysis of metabolic traits in a birth cohort from a founder population

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3062476

Common variants at 30 loci contribute to polygenic dyslipidemia

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3062476

Therapeutic RNAi targeting PCSK9 acutely lowers plasma cholesterol in rodents and LDL cholesterol in nonhuman primates

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3062476

Six new loci associated with blood low-density lipoprotein cholesterol, high-density lipoprotein cholesterol or triglycerides in humans

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3062476

Genome-wide association study identifies genes for biomarkers of cardiovascular disease: serum urate and dyslipidemia

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3062476

Genomewide association analysis of coronary artery disease

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3062476

Sortilin is essential and sufficient for the formation of Glut4 storage vesicles in 3T3-L1 adipocytes

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3062476

Sortilin is essential for proNGF-induced neuronal cell death

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3062476

Monogenic hypercholesterolemia: new insights in pathogenesis and treatment

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3062476

The sortilin cytoplasmic tail conveys Golgi-endosome transport and binds the VHS domain of the GGA2 sorting protein

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3062476

Structural basis for DNA recognition by the basic region leucine zipper transcription factor CCAAT/enhancer-binding protein alpha

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3062476

Newly identified loci that influence lipid concentrations and risk of coronary artery disease

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3062476

Molecular identification of a novel candidate sorting receptor purified from human brain by receptor-associated protein affinity chromatography

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3062476

Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3062476

Association of blood lipids with common DNA sequence variants at 19 genetic loci in the multiethnic United States National Health and Nutrition Examination Survey III.

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3062476

Highly efficient generation of human hepatocyte-like cells from induced pluripotent stem cells

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3062476

The inactivation of the sortilin gene leads to a partial disruption of prosaposin trafficking to the lysosomes

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3062476

Ion mobility analysis of lipoprotein subfractions identifies three independent axes of cardiovascular risk

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3062476

Reversal of small, dense LDL subclass phenotype by normalization of adiposity

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3062476

A combinatorial library of lipid-like materials for delivery of RNAi therapeutics

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3062476

Metabolic origins and clinical significance of LDL heterogeneity

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3062476

A dominant-negative inhibitor of CREB reveals that it is a general mediator of stimulus-dependent transcription of c-fos

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3062476

C/EBP alpha: a critical regulator of genes governing integrative metabolic processes

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3062476

DNA binding specificity of the CCAAT/enhancer-binding protein transcription factor family

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3062476

Design of a C/EBP-specific, dominant-negative bZIP protein with both inhibitory and gain-of-function properties.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3062476

Genetic variation at chromosome 1p13.3 affects sortilin mRNA expression, cellular LDL-uptake and serum LDL levels which translates to the risk of coronary artery disease

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3062476

Lipid treatment assessment project 2: a multinational survey to evaluate the proportion of patients achieving low-density lipoprotein cholesterol goals.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3062476

Complete prevention of atherosclerosis in apoE-deficient mice by hepatic human apoE gene transfer with adeno-associated virus serotypes 7 and 8.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3062476

Therapeutic silencing of an endogenous gene by systemic administration of modified siRNAs

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3062476

Heart attacks: gone with the century?

28 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20686566

12 December 2020

inferred from PubMed ID database lookup

Expression of cholesteryl ester transfer protein in mice promotes macrophage reverse cholesterol transport

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20686566

12 December 2020

inferred from PubMed ID database lookup

Polymorphisms of the HNF1A gene encoding hepatocyte nuclear factor-1 alpha are associated with C-reactive protein

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNATURE09266

7 January 2021

inferred from DOI database lookup

Candidate gene association resource (CARe): design, methods, and proof of concept

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNATURE09266

7 January 2021

inferred from DOI database lookup

Mapping the genetic architecture of gene expression in human liver

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNATURE09266

7 January 2021

inferred from DOI database lookup

Identifiers

DOI

10.1038/NATURE09266

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20686566%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

9 February 2020

1007547666

0 references

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20686566%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

PubMed publication ID

20686566

2 references