(Q24633204)

English

Improved total synthesis of the potent HDAC inhibitor FK228 (FR-901228)

scientific article

In more languages

edit

Statements

instance of

scholarly article

0 references

title

Improved total synthesis of the potent HDAC inhibitor FK228 (FR-901228) (English)

0 references

0 references

1 reference

ChEBI release 2020-05-28

Thomas J Greshock

1

0 references

Deidre M Johns

series ordinal

2

0 references

Yasuo Noguchi

series ordinal

3

0 references

Robert M Williams

series ordinal

4

0 references

language of work or name

English

0 references

publication date

21 February 2008

0 references

published in

Organic Letters

0 references

volume

10

0 references

page(s)

613-6

0 references

issue

4

0 references

cites work

The first biologically active synthetic analogues of FK228, the depsipeptide histone deacetylase inhibitor

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3097137

retrieved

7 April 2017

Histone deacetylase inhibitor FK228 suppresses the Ras-MAP kinase signaling pathway by upregulating Rap1 and induces apoptosis in malignant melanoma

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3097137

retrieved

27 September 2017

Histone deacetylase inhibitors--a new tool to treat cancer

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3097137

retrieved

27 September 2017

FR901228, a novel antitumor bicyclic depsipeptide produced by Chromobacterium violaceum No. 968. III. Antitumor activities on experimental tumors in mice

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3097137

retrieved

27 September 2017

FR901228, a novel antitumor bicyclic depsipeptide produced by Chromobacterium violaceum No. 968. II. Structure determination

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3097137

retrieved

27 September 2017

FR901228, a novel antitumor bicyclic depsipeptide produced by Chromobacterium violaceum No. 968. I. Taxonomy, fermentation, isolation, physico-chemical and biological properties, and antitumor activity

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3097137

retrieved

27 September 2017

Total Synthesis of the Depsipeptide FR-901375

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3097137

retrieved

28 November 2018

FK228 (depsipeptide) as a natural prodrug that inhibits class I histone deacetylases

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3097137

retrieved

28 November 2018

Structurally simple trichostatin A-like straight chain hydroxamates as potent histone deacetylase inhibitors

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3097137

retrieved

28 November 2018

Inhibitors of human histone deacetylase: synthesis and enzyme and cellular activity of straight chain hydroxamates

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3097137

retrieved

28 November 2018

Total synthesis of spiruchostatin A, a potent histone deacetylase inhibitor

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18205373

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Asymmetric Samarium-Reformatsky Reaction of Chiral alpha-Bromoacetyl-2-oxazolidinones with Aldehydes

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18205373

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Total synthesis of RK-397

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18205373

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Histone deacetylase inhibitors

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18205373

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

IMDA-radical cyclization approach to (+)-himbacine

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18205373

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cardiotoxicity of histone deacetylase inhibitor depsipeptide in patients with metastatic neuroendocrine tumors

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18205373

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

0 references

0 references

0 references

ResearchGate publication ID

5646989

0 references

(Q24633204)

Improved total synthesis of the potent HDAC inhibitor FK228 (FR-901228)

Statements

Identifiers

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)