(Q24641829)

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Safety, tolerability, and pharmacokinetics of PA-824 in healthy subjects

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Safety, tolerability, and pharmacokinetics of PA-824 in healthy subjects (English)

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1 reference

Ann M Ginsberg

1

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Martino W Laurenzi

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2

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Doris J Rouse

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3

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Karl D Whitney

series ordinal

4

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Melvin K Spigelman

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5

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language of work or name

English

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publication date

September 2009

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published in

Antimicrobial Agents and Chemotherapy

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volume

53

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issue

9

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page(s)

3720-5

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cites work

PA-824 kills nonreplicating Mycobacterium tuberculosis by intracellular NO release

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PubMed Central

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7 April 2017

Metronidazole is bactericidal to dormant cells of Mycobacterium tuberculosis

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PubMed Central

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7 April 2017

Global incidence of multidrug-resistant tuberculosis

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PubMed Central

reference URL

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retrieved

7 April 2017

Identification of a nitroimidazo-oxazine-specific protein involved in PA-824 resistance in Mycobacterium tuberculosis

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737845

retrieved

7 April 2017

A small-molecule nitroimidazopyran drug candidate for the treatment of tuberculosis

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PubMed Central

reference URL

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7 April 2017

In vitro and in vivo activities of the nitroimidazole CGI 17341 against Mycobacterium tuberculosis

1 reference

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PubMed Central

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retrieved

7 April 2017

Assessment of the effects of the nitroimidazo-oxazine PA-824 on renal function in healthy subjects

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stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737845

retrieved

27 September 2017

Mycobacterium leprae is naturally resistant to PA-824

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stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737845

retrieved

27 September 2017

Combination chemotherapy with the nitroimidazopyran PA-824 and first-line drugs in a murine model of tuberculosis

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stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737845

retrieved

27 September 2017

Preclinical testing of the nitroimidazopyran PA-824 for activity against Mycobacterium tuberculosis in a series of in vitro and in vivo models

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737845

retrieved

27 September 2017

Bactericidal activity of the nitroimidazopyran PA-824 in a murine model of tuberculosis

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737845

retrieved

27 September 2017

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PubMed publication ID

19528280

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(Q24641829)

Safety, tolerability, and pharmacokinetics of PA-824 in healthy subjects

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