(Q33836720)

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Preclinical testing of the nitroimidazopyran PA-824 for activity against Mycobacterium tuberculosis in a series of in vitro and in vivo models

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scholarly article

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Europe PubMed Central

PubMed publication ID

29 July 2017

Preclinical testing of the nitroimidazopyran PA-824 for activity against Mycobacterium tuberculosis in a series of in vitro and in vivo models (English)

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Europe PubMed Central

PubMed publication ID

29 July 2017

Mycobacterium tuberculosis

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9

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Ian M Orme

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Europe PubMed Central

PubMed publication ID

29 July 2017

author name string

Anne J Lenaerts

1

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

Veronica Gruppo

2

1 reference

Europe PubMed Central

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29 July 2017

Karen S Marietta

3

1 reference

Europe PubMed Central

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29 July 2017

Christine M Johnson

4

1 reference

Europe PubMed Central

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29 July 2017

Diane K Driscoll

5

1 reference

Europe PubMed Central

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29 July 2017

Nicholas M Tompkins

6

1 reference

Europe PubMed Central

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29 July 2017

Jerry D Rose

7

1 reference

Europe PubMed Central

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29 July 2017

Robert C Reynolds

8

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29 July 2017

language of work or name

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publication date

1 June 2005

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29 July 2017

Antimicrobial Agents and Chemotherapy

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Europe PubMed Central

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29 July 2017

49

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Europe PubMed Central

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29 July 2017

6

1 reference

Europe PubMed Central

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29 July 2017

2294-2301

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

Predictive in vitro models of the sterilizing activity of anti-tuberculosis drugs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1140539

4 July 2018

The search for new sterilizing anti-tuberculosis drugs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1140539

4 July 2018

Structure, function, and biogenesis of the cell wall of Mycobacterium tuberculosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1140539

4 July 2018

Antitubercular isoniazid and drug resistance of Mycobacterium tuberculosis--a review

1 reference

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Rapid in vivo screening of experimental drugs for tuberculosis using gamma interferon gene-disrupted mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1140539

4 July 2018

Drugs that inhibit mycolic acid biosynthesis in Mycobacterium tuberculosis

1 reference

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4 July 2018

Controlling multidrug-resistant tuberculosis and access to expensive drugs: a rational framework

1 reference

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4 July 2018

Demonstration that fbiC is required by Mycobacterium bovis BCG for coenzyme F(420) and FO biosynthesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1140539

4 July 2018

Use of transposon Tn5367 mutagenesis and a nitroimidazopyran-based selection system to demonstrate a requirement for fbiA and fbiB in coenzyme F(420) biosynthesis by Mycobacterium bovis BCG

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1140539

4 July 2018

Search for new drugs for treatment of tuberculosis

1 reference

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4 July 2018

Bactericidal activity of nitrofurans against growing and dormant Mycobacterium bovis BCG.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1140539

4 July 2018

A small-molecule nitroimidazopyran drug candidate for the treatment of tuberculosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1140539

4 July 2018

Activity of quinolones against mycobacteria

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1140539

4 July 2018

Metronidazole therapy in mice infected with tuberculosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1140539

4 July 2018

Evaluation of once-weekly therapy for tuberculosis using isoniazid plus rifamycins in the mouse aerosol infection model

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1140539

4 July 2018

Low-dose aerosol infection model for testing drugs for efficacy against Mycobacterium tuberculosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1140539

4 July 2018

An in vitro model for sequential study of shiftdown of Mycobacterium tuberculosis through two stages of nonreplicating persistence

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1140539

4 July 2018

In vitro and in vivo activities of the nitroimidazole CGI 17341 against Mycobacterium tuberculosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1140539

4 July 2018

Disseminated tuberculosis in interferon gamma gene-disrupted mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1140539

4 July 2018

The clinical spectrum of primary tuberculosis in adults. Confusion with reinfection in the pathogenesis of chronic tuberculosis

1 reference

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4 July 2018

Pathogenesis of a first episode of chronic pulmonary tuberculosis in man: recrudescence of residuals of the primary infection or exogenous reinfection?

1 reference

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4 July 2018

Structural alterations that differentially affect the mutagenic and antitrichomonal activities of 5-nitroimidazoles

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1140539

4 July 2018

Susceptibility testing of slowly growing mycobacteria by a microdilution MIC method with 7H9 broth

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1140539

4 July 2018

Nitroimidazoles, Part XXIII--activity of satranidazole series against anaerobic infections

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1140539

4 July 2018

Potential radiosensitizing agents. Dinitroimidazoles

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1140539

4 July 2018

Mode of action of rifampin on mycobacteria. II. Biosynthetic studies on the inhibition of ribonucleic acid polymerase of Mycobacterium bovis BCG by rifampin and uptake of rifampin- 14 C by Mycobacterium phlei

1 reference

https://pubmed.ncbi.nlm.nih.gov/15917524

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mycobacteria. General culture methodology and safety considerations

1 reference

https://pubmed.ncbi.nlm.nih.gov/15917524

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1128/AAC.49.6.2294-2301.2005

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

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