(Q24644867)

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Activation of metallothioneins and alpha-crystallin/sHSPs in human lens epithelial cells by specific metals and the metal content of aging clear human lenses

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scholarly article

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Activation of metallothioneins and alpha-crystallin/sHSPs in human lens epithelial cells by specific metals and the metal content of aging clear human lenses (English)

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author name string

John R Hawse

1

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Jonathan R Cumming

2

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Brian Oppermann

3

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Nancy L Sheets

4

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Venkat N Reddy

5

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Marc Kantorow

6

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language of work or name

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publication date

February 2003

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Investigative Ophthalmology Visual Science

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44

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2

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672-9

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Identification and spatial analysis of metallothioneins expressed by the adult human lens

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825746

7 April 2017

Embryonic lethality and liver degeneration in mice lacking the metal-responsive transcriptional activator MTF-1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825746

7 April 2017

Structure and expression of the human metallothionein-IG gene. Differential promoter activity of two linked metallothionein-I genes in response to heavy metals

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825746

7 April 2017

Molecular basis for the recently described hereditary hyperferritinemia-cataract syndrome: a mutation in the iron-responsive element of ferritin L-subunit gene (the "Verona mutation")

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825746

7 April 2017

The molecular chaperone alphaA-crystallin enhances lens epithelial cell growth and resistance to UVA stress

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825746

7 April 2017

Targeted disruption of the mouse alpha A-crystallin gene induces cataract and cytoplasmic inclusion bodies containing the small heat shock protein alpha B-crystallin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825746

7 April 2017

The transcription factor MTF-1 is essential for basal and heavy metal-induced metallothionein gene expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825746

7 April 2017

Characterization of DNA sequences through which cadmium and glucocorticoid hormones induce human metallothionein-IIA gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825746

7 April 2017

Metallothionein protects retinal pigment epithelial cells against apoptosis and oxidative stress

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825746

27 September 2017

The R116C mutation in alpha A-crystallin diminishes its protective ability against stress-induced lens epithelial cell apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825746

27 September 2017

Metallothionein overexpression in human trophoblastic cells protects against cadmium-induced apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825746

27 September 2017

Differential protective activity of alpha A- and alphaB-crystallin in lens epithelial cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825746

27 September 2017

Vasopressin stimulates the induction of heat shock protein 27 and alphaB-crystallin via protein kinase C activation in vascular smooth muscle cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825746

27 September 2017

Human lens epithelial cell line

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825746

27 September 2017

Human and monkey trabecular meshwork accumulate alpha B-crystallin in response to heat shock and oxidative stress

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825746

27 September 2017

Targeting and germ-line transmission of a null mutation at the metallothionein I and II loci in mouse

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825746

27 September 2017

Targeted disruption of metallothionein I and II genes increases sensitivity to cadmium

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825746

27 September 2017

Smoking of beedies and cataract: cadmium and vitamin C in the lens and blood

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825746

27 September 2017

Lens differentiation in vertebrates. A review of cellular and molecular features

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825746

27 September 2017

Metabolism of glutathione in the lens

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825746

27 September 2017

Induction of metallothionein and other mRNA species by carcinogens and tumor promoters in primary human skin fibroblasts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825746

27 September 2017

Biochemistry of metallothionein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825746

27 September 2017

Coordinate induction of metallothioneins I and II in rodent cells by UV irradiation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825746

27 September 2017

Multiple mRNAs of rat brain alpha-crystallin B chain result from alternative transcriptional initiation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825746

27 September 2017

AlphaB-crystallin in the trabecular meshwork is inducible by transforming growth factor-beta

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825746

30 May 2018

Glucocorticoids regulate the expression of the stressprotein alpha B-crystallin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825746

30 May 2018

Epidemiological and other studies in the assessment of factors contributing to cataractogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825746

30 May 2018

Hypertonic stress induces alpha B-crystallin expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825746

30 May 2018

Translocation and induction of alpha B crystallin by heat shock in rat glioma (GA-1) cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825746

28 July 2018

Effect of ultraviolet A on ornithine decarboxylase and metallothionein gene expression in mouse skin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825746

28 November 2018

Differential gene expression in male and female rat lenses undergoing cataract induction by transforming growth factor-beta (TGF-beta).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825746

28 November 2018

Wilson's disease. Update of a systemic disorder with protean manifestations.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825746

28 November 2018

Differential display detects altered gene expression between cataractous and normal human lenses.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825746

28 November 2018

Complete structure and expression of the rat alpha B-crystallin gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825746

28 November 2018

Transcription regulation of alpha B-crystallin in astrocytes: analysis of HSF and AP1 activation by different types of physiological stress

1 reference

https://pubmed.ncbi.nlm.nih.gov/12556398

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antioxidant activity of metallothionein compared with reduced glutathione

1 reference

https://pubmed.ncbi.nlm.nih.gov/12556398

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protective effect of metallothionein against the toxicity of cadmium and other metals(1)

1 reference

https://pubmed.ncbi.nlm.nih.gov/12556398

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Accumulation of cadmium by the eye with special reference to the lens

1 reference

https://pubmed.ncbi.nlm.nih.gov/12556398

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differentiation of human lens epithelial cells in tissue culture

1 reference

https://pubmed.ncbi.nlm.nih.gov/12556398

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increase in metallothionein produced by chemicals that induce oxidative stress

1 reference

https://pubmed.ncbi.nlm.nih.gov/12556398

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Possible chemical pollution

1 reference

https://pubmed.ncbi.nlm.nih.gov/12556398

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The effect of hypertonicity on aldose reductase, alpha B-crystallin, and organic osmolytes in the retinal pigment epithelium

1 reference

https://pubmed.ncbi.nlm.nih.gov/12556398

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Induction of the synthesis of hsp27 and alpha B crystallin in tissues of heat-stressed rats and its suppression by ethanol or an alpha 1-adrenergic antagonist

1 reference

https://pubmed.ncbi.nlm.nih.gov/12556398

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Metallothionein plays less of a protective role in cadmium-metallothionein-induced nephrotoxicity than in cadmium chloride-induced hepatotoxicity

1 reference

https://pubmed.ncbi.nlm.nih.gov/12556398

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Metallothionein I and II protect against zinc deficiency and zinc toxicity in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/12556398

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1167/IOVS.02-0018

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