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Neural KCNQ (Kv7) channels
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scholarly article
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review article
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Europe PubMed Central
title
Neural KCNQ (Kv7) channels
(English)
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author name string
David A Brown
series ordinal
1
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Gayle M Passmore
series ordinal
2
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language of work or name
English
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publication date
April 2009
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published in
British Journal of Pharmacology
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volume
156
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page(s)
1185-95
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issue
8
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cites work
Polarized axonal surface expression of neuronal KCNQ channels is mediated by multiple signals in the KCNQ2 and KCNQ3 C-terminal domains
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A common ankyrin-G-based mechanism retains KCNQ and NaV channels at electrically active domains of the axon
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Retigabine, a novel anti-convulsant, enhances activation of KCNQ2/Q3 potassium channels
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Stoichiometry of expressed KCNQ2/KCNQ3 potassium channels and subunit composition of native ganglionic M channels deduced from block by tetraethylammonium
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N-(6-chloro-pyridin-3-yl)-3,4-difluoro-benzamide (ICA-27243): a novel, selective KCNQ2/Q3 potassium channel activator.
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Zinc pyrithione-mediated activation of voltage-gated KCNQ potassium channels rescues epileptogenic mutants
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Anxiolytic effects of Maxipost (BMS-204352) and retigabine via activation of neuronal Kv7 channels.
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KCNQ4 channel activation by BMS-204352 and retigabine
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Molecular basis for differential sensitivity of KCNQ and I(Ks) channels to the cognitive enhancer XE991.
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Control of M-current
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Slow synaptic transmission in frog sympathetic ganglia
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Blockade of Ca-activated K conductance by apamin in rat sympathetic neurones
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Muscarinic agonists block five different potassium conductances in guinea-pig sympathetic neurones
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In vivo profile of ICA-27243 [N-(6-chloro-pyridin-3-yl)-3,4-difluoro-benzamide], a potent and selective KCNQ2/Q3 (Kv7.2/Kv7.3) activator in rodent anticonvulsant models
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Retigabine reduces the excitability of unmyelinated peripheral human axons
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28 November 2018
Spike Ca2+ influx upmodulates the spike afterdepolarization and bursting via intracellular inhibition of KV7/M channels
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28 November 2018
The KCNQ/M-current modulates arterial baroreceptor function at the sensory terminal in rats
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28 November 2018
Pharmacological comparison of anticonvulsant drugs in animal models of persistent pain and anxiety.
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28 November 2018
The neuronal KCNQ channel opener retigabine inhibits locomotor activity and reduces forebrain excitatory responses to the psychostimulants cocaine, methylphenidate and phencyclidine.
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28 November 2018
PIP(2)-dependent inhibition of M-type (Kv7.2/7.3) potassium channels: direct on-line assessment of PIP(2) depletion by Gq-coupled receptors in single living neurons.
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28 November 2018
Requirement of subunit co-assembly and ankyrin-G for M-channel localization at the axon initial segment.
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28 November 2018
The acrylamide (S)-1 differentially affects Kv7 (KCNQ) potassium channels.
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28 November 2018
Probing the regulation of M (Kv7) potassium channels in intact neurons with membrane-targeted peptides.
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28 November 2018
Angiotensin II regulates neuronal excitability via phosphatidylinositol 4,5-bisphosphate-dependent modulation of Kv7 (M-type) K+ channels.
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28 November 2018
KCNQ channels mediate IKs, a slow K+ current regulating excitability in the rat node of Ranvier
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28 November 2018
Molecular determinants of KCNQ (Kv7) K+ channel sensitivity to the anticonvulsant retigabine.
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28 November 2018
Relationship between membrane phosphatidylinositol-4,5-bisphosphate and receptor-mediated inhibition of native neuronal M channels.
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28 November 2018
The new anticonvulsant retigabine favors voltage-dependent opening of the Kv7.2 (KCNQ2) channel by binding to its activation gate
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28 November 2018
Conditional transgenic suppression of M channels in mouse brain reveals functions in neuronal excitability, resonance and behavior.
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28 November 2018
Meclofenamic acid and diclofenac, novel templates of KCNQ2/Q3 potassium channel openers, depress cortical neuron activity and exhibit anticonvulsant properties
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28 November 2018
KCNQ/M channels control spike afterdepolarization and burst generation in hippocampal neurons.
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28 November 2018
The anti-hyperalgesic activity of retigabine is mediated by KCNQ potassium channel activation
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28 November 2018
KCNQ2 is a nodal K+ channel.
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28 November 2018
KCNQ/M currents in sensory neurons: significance for pain therapy.
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28 November 2018
Effect of the KCNQ potassium channel opener retigabine on single KCNQ2/3 channels expressed in CHO cells
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28 November 2018
PIP(2) activates KCNQ channels, and its hydrolysis underlies receptor-mediated inhibition of M currents
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28 November 2018
The anticonvulsant retigabine attenuates nociceptive behaviours in rat models of persistent and neuropathic pain
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28 November 2018
Molecular correlates of the M-current in cultured rat hippocampal neurons
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28 November 2018
Recovery from muscarinic modulation of M current channels requires phosphatidylinositol 4,5-bisphosphate synthesis
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28 November 2018
Effects of the anticonvulsant retigabine on cultured cortical neurons: changes in electroresponsive properties and synaptic transmission
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28 November 2018
Activation of expressed KCNQ potassium currents and native neuronal M-type potassium currents by the anti-convulsant drug retigabine.
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28 November 2018
Potassium currents in rat prevertebral and paravertebral sympathetic neurones: control of firing properties.
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28 November 2018
The therapeutic potential of neuronal K V 7 (KCNQ) channel modulators: an update
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1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/19298256
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Retigabine-induced population primary afferent hyperpolarisation in vitro
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/19298256
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
M currents.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1111%2FJ.1476-5381.2009.00111.X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Two components of muscarine-sensitive membrane current in rat sympathetic neurones.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1111%2FJ.1476-5381.2009.00111.X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1111/J.1476-5381.2009.00111.X
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
1412972
OpenCitations bibliographic resource ID
1412972
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
1412972
PMCID
2697739
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
1412972
PubMed ID
19298256
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
1412972
ResearchGate publication ID
24212164
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