(Q24645530)

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Access of antibody molecules to the conserved coreceptor binding site on glycoprotein gp120 is sterically restricted on primary human immunodeficiency virus type 1

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Access of antibody molecules to the conserved coreceptor binding site on glycoprotein gp120 is sterically restricted on primary human immunodeficiency virus type 1 (English)

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Joseph Sodroski

18

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Joseph Sodroski

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Pascal Poignard

2

object named as

Pascal Poignard

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Christos J Petropoulos

12

object named as

Christos J Petropoulos

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16

object named as

Peter D Kwong

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Dennis R. Burton

19

object named as

Dennis R Burton

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Richard T. Wyatt

17

object named as

Richard T Wyatt

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author name string

Aran F Labrijn

1

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Aarti Raja

3

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Michael B Zwick

4

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Karla Delgado

5

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Michael Franti

6

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James Binley

7

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Veronique Vivona

8

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Christoph Grundner

9

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Chih-Chin Huang

10

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Miro Venturi

11

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Terri Wrin

13

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Dimiter S Dimitrov

14

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James Robinson

15

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publication date

October 2003

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Journal of Virology

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77

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19

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10557-65

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Energetics of the HIV gp120-CD4 binding reaction

1 reference

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Crystal structure of a neutralizing human IGG against HIV-1: a template for vaccine design

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Structures of HIV-1 gp120 envelope glycoproteins from laboratory-adapted and primary isolates

1 reference

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Structure of an HIV gp120 envelope glycoprotein in complex with the CD4 receptor and a neutralizing human antibody

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The CCP4 suite: programs for protein crystallography

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HIV-1 evades antibody-mediated neutralization through conformational masking of receptor-binding sites

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Human monoclonal antibody 2G12 defines a distinctive neutralization epitope on the gp120 glycoprotein of human immunodeficiency virus type 1

2 references

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Efficient neutralization of primary isolates of HIV-1 by a recombinant human monoclonal antibody

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Broadly cross-reactive HIV-1-neutralizing human monoclonal Fab selected for binding to gp120-CD4-CCR5 complexes

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Highly stable trimers formed by human immunodeficiency virus type 1 envelope glycoproteins fused with the trimeric motif of T4 bacteriophage fibritin

1 reference

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Neutralization synergy of human immunodeficiency virus type 1 primary isolates by cocktails of broadly neutralizing antibodies.

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Antigenic properties of the human immunodeficiency virus envelope during cell-cell fusion

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The antiviral activity of antibodies in vitro and in vivo.

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Loss of a single N-linked glycan allows CD4-independent human immunodeficiency virus type 1 infection by altering the position of the gp120 V1/V2 variable loops

1 reference

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Expression and characterization of a single-chain polypeptide analogue of the human immunodeficiency virus type 1 gp120-CD4 receptor complex

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V2 loop glycosylation of the human immunodeficiency virus type 1 SF162 envelope facilitates interaction of this protein with CD4 and CCR5 receptors and protects the virus from neutralization by anti-V3 loop and anti-CD4 binding site antibodies

1 reference

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Variable-loop-deleted variants of the human immunodeficiency virus type 1 envelope glycoprotein can be stabilized by an intermolecular disulfide bond between the gp120 and gp41 subunits

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A recombinant human immunodeficiency virus type 1 envelope glycoprotein complex stabilized by an intermolecular disulfide bond between the gp120 and gp41 subunits is an antigenic mimic of the trimeric virion-associated structure

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Sequential CD4-coreceptor interactions in human immunodeficiency virus type 1 Env function: soluble CD4 activates Env for coreceptor-dependent fusion and reveals blocking activities of antibodies against cryptic conserved epitopes on gp120.

1 reference

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Stoichiometry of monoclonal antibody neutralization of T-cell line-adapted human immunodeficiency virus type 1

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Adaptation of a CCR5-using, primary human immunodeficiency virus type 1 isolate for CD4-independent replication

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Stable exposure of the coreceptor-binding site in a CD4-independent HIV-1 envelope protein

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Use of coreceptors other than CCR5 by non-syncytium-inducing adult and pediatric isolates of human immunodeficiency virus type 1 is rare in vitro

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CD4-dependent, antibody-sensitive interactions between HIV-1 and its co-receptor CCR-5.

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CD4-induced interaction of primary HIV-1 gp120 glycoproteins with the chemokine receptor CCR-5.

1 reference

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Physicochemical dissociation of CD4-mediated syncytium formation and shedding of human immunodeficiency virus type 1 gp120.

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Differential regulation of cellular tropism and sensitivity to soluble CD4 neutralization by the envelope gp120 of human immunodeficiency virus type 1.

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1 reference

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1 reference

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1 reference

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1 reference

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gp120: Biologic aspects of structural features

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Probability analysis of variational crystallization and its application to gp120, the exterior envelope glycoprotein of type 1 human immunodeficiency virus (HIV-1).

1 reference

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Fine definition of a conserved CCR5-binding region on the human immunodeficiency virus type 1 glycoprotein 120

1 reference

https://pubmed.ncbi.nlm.nih.gov/12970440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fusin--a place for HIV-1 and T4 cells to meet

1 reference

https://pubmed.ncbi.nlm.nih.gov/12970440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1128/JVI.77.19.10557-10565.2003

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

OpenCitations bibliographic resource ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

PMC publication ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

PubMed publication ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

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