(Q24645675)

English

Safety, pharmacokinetics, and antiretroviral activity of multiple doses of ibalizumab (formerly TNX-355), an anti-CD4 monoclonal antibody, in human immunodeficiency virus type 1-infected adults

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scholarly article

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Safety, pharmacokinetics, and antiretroviral activity of multiple doses of ibalizumab (formerly TNX-355), an anti-CD4 monoclonal antibody, in human immunodeficiency virus type 1-infected adults (English)

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anti-retroviral agent

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pharmacokinetics

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based on heuristic

inferred from title

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based on heuristic

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monoclonal antibody

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Daniel Kuritzkes

2

object named as

Daniel R Kuritzkes

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author name string

Jeffrey M Jacobson

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Eliot Godofsky

3

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Edwin DeJesus

4

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Jeffrey A Larson

5

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Steven P Weinheimer

6

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Stanley T Lewis

7

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language of work or name

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publication date

February 2009

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Antimicrobial Agents and Chemotherapy

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53

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2

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450-7

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Enfuvirtide, an HIV-1 fusion inhibitor, for drug-resistant HIV infection in North and South America

1 reference

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7 April 2017

Declining morbidity and mortality among patients with advanced human immunodeficiency virus infection. HIV Outpatient Study Investigators

1 reference

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Reduced maximal inhibition in phenotypic susceptibility assays indicates that viral strains resistant to the CCR5 antagonist maraviroc utilize inhibitor-bound receptor for entry

1 reference

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27 September 2017

Immune responses to therapeutic proteins in humans--clinical significance, assessment and prediction

1 reference

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27 September 2017

Modification of the Fc region of a primatized IgG antibody to human CD4 retains its ability to modulate CD4 receptors but does not deplete CD4(+) T cells in chimpanzees

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2630626

27 September 2017

The relation between baseline HIV drug resistance and response to antiretroviral therapy: re-analysis of retrospective and prospective studies using a standardized data analysis plan.

1 reference

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27 September 2017

Metabolism of immunoglobulins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2630626

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Mouse/human chimeric monoclonal antibody in man: kinetics and immune response

1 reference

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27 September 2017

Differential effects of administration of a human anti-CD4 monoclonal antibody, HM6G, in nonhuman primates

1 reference

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30 May 2018

A primatized MAb to human CD4 causes receptor modulation, without marked reduction in CD4+ T cells in chimpanzees: in vitro and in vivo characterization of a MAb (IDEC-CE9.1) to human CD4.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2630626

30 May 2018

In vivo administration to rhesus monkeys of a CD4-specific monoclonal antibody capable of blocking AIDS virus replication

1 reference

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30 May 2018

Inhibition of HIV infection by a novel CD4 domain 2-specific monoclonal antibody. Dissecting the basis for its inhibitory effect on HIV-induced cell fusion

1 reference

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30 May 2018

Antiretroviral activity of the anti-CD4 monoclonal antibody TNX-355 in patients infected with HIV type 1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2630626

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1 reference

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Functional epitope analysis of the human CD4 molecule. The MHC class II-dependent activation of resting T cells is inhibited by monoclonal antibodies to CD4 regardless whether or not they recognize epitopes involved in the binding of MHC class II or

1 reference

https://pubmed.ncbi.nlm.nih.gov/19015347

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Immunosuppression of cynomolgus renal allograft recipients with humanized OKT4A monoclonal antibodies

1 reference

https://pubmed.ncbi.nlm.nih.gov/19015347

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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