(Q24646209)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19935799%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

title

A phase I study of the nitroimidazole hypoxia marker SR4554 using 19F magnetic resonance spectroscopy (English)

1 reference

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12 February 2020

0 references

3

1 reference

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12 February 2020

Florence Raynaud

6

1 reference

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12 February 2020

Martin Leach

14

1 reference

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12 February 2020

author name string

C P Lee

1

1 reference

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12 February 2020

G S Payne

2

1 reference

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12 February 2020

R Ruddle

4

1 reference

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12 February 2020

S Tan

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19935799%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

D Eaton

7

1 reference

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12 February 2020

M J Campbell

8

1 reference

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12 February 2020

K Cross

9

1 reference

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12 February 2020

G Halbert

10

1 reference

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12 February 2020

M Tracy

11

1 reference

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12 February 2020

J McNamara

12

1 reference

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12 February 2020

B Seddon

13

1 reference

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12 February 2020

P Workman

15

1 reference

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12 February 2020

I Judson

16

1 reference

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12 February 2020

language of work or name

English

0 references

publication date

1 December 2009

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19935799%20AND%20SRC:MED&resulttype=core&format=json

British Journal of Cancer

12 February 2020

published in

1 reference

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12 February 2020

volume

101

1 reference

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12 February 2020

issue

11

1 reference

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12 February 2020

page(s)

1860-1868

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19935799%20AND%20SRC:MED&resulttype=core&format=json

Simultaneous in vivo positron emission tomography and magnetic resonance imaging.

12 February 2020

cites work

1 reference

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Quantitative assessment of the hepatic pharmacokinetics of the antimicrobial sitafloxacin in humans using in vivoF magnetic resonance spectroscopy

27 September 2017

1 reference

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Endogenous markers of tumor hypoxia predictors of clinical radiation resistance?

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2788261

A phase I study of SR-4554 via intravenous administration for noninvasive investigation of tumor hypoxia by magnetic resonance spectroscopy in patients with malignancy

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2788261

Invasive oxygen measurements and pimonidazole labeling in human cervix carcinoma.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2788261

Oxygenation predicts radiation response and survival in patients with cervix cancer

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2788261

Preclinical development and current status of the fluorinated 2-nitroimidazole hypoxia probe N-(2-hydroxy-3,3,3-trifluoropropyl)-2-(2-nitro-1-imidazolyl) acetamide (SR 4554, CRC 94/17): a non-invasive diagnostic probe for the measurement of tumor hy

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2788261

The relationship between tumour oxygenation determined by oxygen electrode measurements and magnetic resonance spectroscopy of the fluorinated 2-nitroimidazole SR-4554.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2788261

The novel fluorinated 2-nitroimidazole hypoxia probe SR-4554: reductive metabolism and semiquantitative localisation in human ovarian cancer multicellular spheroids as measured by electron energy loss spectroscopic analysis

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2788261

A marker for hypoxic cells in tumours with potential clinical applicability

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2788261

Binding of misonidazole to hypoxic cells in monolayer and spheroid culture: evidence that a side-chain label is bound as efficiently as a ring label

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2788261

Measurement of tumor hypoxia by invasive and non-invasive procedures: a review of recent clinical studies

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2788261

27 September 2017

Bioreductive mechanisms

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2788261

The use of nitroaromatic compounds as hypoxic cell radiosensitizers

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2788261

The pharmacokinetics, bioavailability and biodistribution in mice of a rationally designed 2-nitroimidazole hypoxia probe SR-4554.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2788261

Effect of hyperthermia on differential cytotoxicity of a hypoxic cell radiosensitizer, Ro-07-0582, on mammalian cells in vitro

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2788261

Oxygenation of head and neck cancer: changes during radiotherapy and impact on treatment outcome

30 May 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BJC.6605425

Tumor hypoxia imaging with [F-18] fluoromisonidazole positron emission tomography in head and neck cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BJC.6605425

Prognostic significance of [18F]-misonidazole positron emission tomography-detected tumor hypoxia in patients with advanced head and neck cancer randomly assigned to chemoradiation with or without tirapazamine: a substudy of Trans-Tasman Radiation O

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BJC.6605425

Simultaneous MR/PET imaging of the human brain: feasibility study

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BJC.6605425

Novel non-invasive probes for measuring tumor-hypoxia by 19F-magnetic resonance spectroscopy (19F-MRS). Studies in the SCCVII/C3H murine model.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2788261

Prognostic impact of hypoxia imaging with 18F-misonidazole PET in non-small cell lung cancer and head and neck cancer before radiotherapy.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2788261

Validation of the fluorinated 2-nitroimidazole SR-4554 as a noninvasive hypoxia marker detected by magnetic resonance spectroscopy

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2788261

Repeatability and prognostic impact of the pretreatment pO(2) histography in patients with advanced head and neck cancer

28 November 2018

1 reference

12 December 2020

Intracellular localization of radioactively labeled misonidazole in EMT-6-tumor cells in vitro

1 reference

12 December 2020

Characteristics of the metabolism-induced binding of misonidazole to hypoxic mammalian cells

1 reference

12 December 2020

The role of specific reductases in the intracellular activation and binding of 2-nitroimidazoles

1 reference

12 December 2020

Development and validation of a solid-phase extraction and high-performance liquid chromatographic assay for a novel fluorinated 2-nitroimidazole hypoxia probe (SR-4554) in Balb/c mouse plasma

1 reference

12 December 2020

Tumor oxygenation predicts for the likelihood of distant metastases in human soft tissue sarcoma

1 reference

12 December 2020

Association between tumor hypoxia and malignant progression in advanced cancer of the uterine cervix

1 reference

12 December 2020

Pretreatment oxygenation predicts radiation response in advanced squamous cell carcinoma of the head and neck

1 reference

12 December 2020

Preclinical evaluation of the fluorinated 2-nitroimidazole N-(2-hydroxy-3,3,3-trifluoropropyl)-2-(2-nitro-1-imidazolyl) acetamide (SR-4554) as a probe for the measurement of tumor hypoxia

1 reference

12 December 2020

Bioreductive metabolism of the novel fluorinated 2-nitroimidazole hypoxia probe N-(2-hydroxy-3,3,3-trifluoropropyl)-2-(2-nitroimidazolyl) acetamide (SR-4554)

1 reference

12 December 2020

Use of 2-nitroimidazoles as bioreductive markers for tumour hypoxia

1 reference

12 December 2020

Influence of the hypoxic subvolume on the survival of patients with head and neck cancer

1 reference

12 December 2020

In vivo 19F magnetic resonance spectroscopy and chemical shift imaging of tri-fluoro-nitroimidazole as a potential hypoxia reporter in solid tumors

1 reference

12 December 2020

Partition coefficient as a guide to the development of radiosensitizers which are less toxic than misonidazole

1 reference

12 December 2020

Binding to cellular macromolecules as a possible mechanism for the cytotoxicity of misonidazole

1 reference

12 December 2020

Structure-pharmacokinetic relationships for misonidazole analogues in mice

1 reference

12 December 2020

Identifiers

DOI

10.1038/SJ.BJC.6605425

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19935799%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

12 February 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19935799%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

PubMed publication ID

19935799

1 reference